a little bit on motor neuron disease Flashcards

Just a little deck of cards on motor neurone disease.

1
Q

motor neuron disease risk factors

A

inherited

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2
Q

pathology of motor neuron disease

A

selective loss of neurons

collection of diseases - most common is amyotrophic lateral sclerosis (ALS)

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3
Q

signs of upper motor neuron disease

A

everything goes up:
spasticity
Babinksi sign
brisk reflexes

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4
Q

signs of lower motor neuron disease

A
everything goes down:
reduced muscle tone
muscle wasting
fasciculation 
reflexes depressed
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5
Q

diagnosis of motor neuron disease

A

diagnosis by exclusion
blood tests for muscle enzymes and autoantibodies
lumbar puncture
MRI head/spine
nerve conduction studies - electromyography

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6
Q

treatment of motor neuron disease

A

anti-glutamergic drugs e.g. riluzole

symptom management - e.g. amitriptyline for drooling

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