Lidocaine Drug sheet

Question 1

What is the mode of action?

Answer 1

Sodium channel blocker- interrupts impulse conduction in peripheral nerves and stabilises editable cell membranes

Question 2

What are the contraindications?

Answer 2

Know hypersensitivity to lidocaine or related local anaesthetics
-bupivacaine, levobupivacain, prilocaine and ropivacaine

Question 3

What are the precautions?

Answer 3

IM and local infiltration- inadvertent intravascular administration may result in systemic toxicity.
IO- impaired CV function

Question 4

what are the adverse effects?

Answer 4

Allergic reactions are rare but may present as localises oedema, urticaria, bronchospasm and anaphylaxis

Question 5

What are the sings of systemic toxicity?

Answer 5

CNS: tinnitus, blurred vison, sudden change in consciousness, afgitation, convulsions
CV: Hypotension, bradycardia, arythmias, cardiac arrest

Question 6

What is the presentation?

Answer 6

50mg in 5ml ampule

Question 7

What is the onset and duration of action?

Answer 7

1-5 minutes infiltration
5-15 minutes other routes
Duration 1-1.5 hours