Lecture 9: GI I- oral cavity Flashcards
What is the primary function or oral cavity
take in food—> chew—> moisten—> swallow
what type of epithelium makes up gingiva and oral mucosa
stratified squamous epithelium
Identify 1-2
- Oral mucosa
- Gingiva
the tongue is coated in __, supported by a core of __
oral mucosa, skeletal muscle
what arrow pointing to
dental pad
what on tongue/ oral mucosa
papillae
what is involved in defense in oral cavity
- Mucosa coating
- Antibacterial compounds- hydrogen peroxide, secretory IgA
- Digestive enzymes
- Normal flora
- Epithelial barrier
- Lymphoid tissue- tonsils
What wrong and what predisposed to
cleft palate- predisposed to aspiration pneumonia
what wrong
Brachygnathia superior- maxilla shorter than mandible
what wrong
Brachygnathia inferior-mandible shorter than maxilla
inflammation of oral cavity
stomatitis
Inflammation of tongue
glossitis
inflammation of gums
gingivitis
inflammation of caudal oral cavity
faucitis
inflammation of lips
chelitis
inflammation of salivary glands
sialoadentitis
what are 2 potential consequences of stomatitis
- Hypersalivation
- Osteomyelitis
identify lesions 1-3
- Papule
- Vesicle
- Erosion/ulceration
what are some clinical signs of stomatitis and gingivitis
hypersalivation and anorexia
what viruses cause papular stomatitis
pox viruses
what viruses cause vesicular stomatitis
- FMD
- Vesicular stomatitis
- Vesicular exanthema of swine
- Swine vesicular disease
cow- what wrong and what cause
Bovine papular stomatitis
Cause: bovine parapox virus
vesicular lesions must be distinguished from ___first
FMD
what is the cause of FMD
picornavirus
What is cause of vesicular stomatitis
rhabdovirus
what causes vesicular exanthema of swine
calicivirus
what causes swine vesicualr disease
enterovirus
what are some gross lesions of all vesicular stomatitides
vesicles/blisters, ulcers of oral cavities
what are the microscopic lesions of all vesicular stomatitides
vesicles within epithelium—> erosion/necrosis
how do you dx vesicular stomatitides
PCR
what should you do first when you suspect vesicular stomatitides
contact state vet
Who does FMD affect
calves and pigs
is FMD in U.S.
no
how is FMD transmitted
direct contact, aerosol
what is the only vesicular stomatitides horses get
vesicular stomatitis virus
what wrong and what cause
FMD
Cause: picornavirus
What wrong and what are two potential dx
ulcerative stomatitis
Dx: FHV-1 or calicivirus
what are some causes for erosive and ulcerative stomatitis in ruminants (not vesicular)
- BVDV
- MCF
- Bluetongue
- IBR or BHV-1
what is the cause of BVDV
pestivirus
what are the two strains of BVDV
non-cytopathic and cytopathic
what are the two forms of GI disease caused by BVDV and associated morbidity and mortality
- Viral disease- low morality, high morbidity
- Mucosal disease- high mortality, low morbidity
describe the non cytopathic and cytopathic strains of BVDV
- Non-cytopathic: exposed 30-110 days gestation—>persistent infection—> calf exposed after birth to cytopathic strain—> mucosal disease
- Cytopathic strain—> exposed before 30-110 days—> early embryonic death, abortion, cerebellar hypoplasia
what are some gross lesions associated with mucosal disease BVDV
erosions/uclers on muzzle, oral cavity, esophagus, small intestines over Peyers patches
based on these lesions what you concerned about
Mucosal disease from BVDV
what is the cause of malignant catarrhal fever
herpesvirus, most common ovine herpesvirus 2
what does MCF cause
fever, diarrhea, hemorrhagic gastroenteritis
cattle with MCF most common become infected after exposure to __
sheep carriers
what is a unique gross lesion of MCF
corneal opacity/ corneal edema
what is the main microscopic lesion for MCF
vasculitis
how do you dx MCF
PCR
cow presents with oral ulcers, diarrhea, corneal edema. Owner informs you they also live with sheep. Perform histopath. What you concerned about
MCF- vasculitis in histo
what wrong and what organ you concerned about
Ulcerative uremic glossitis
Concern for kidneys
what causes pseudomembranous glossitis in horses (thrush)
candida spp
arabian foal presents to necropsy floor, euthanized due to constant repeated infections and very ill. This is tongue from horse what is wrong
Pseudomembranous glossitis caused by candida spp
what species/breed is classic presentation for pseudomembranous glossitis
Arabian foal with SCID- lack functional B and T lymphocytes
what is the cause of lumpy jaw in cattle
actinomyces Bovis
what is cause of wooden tongue in cattle
actinobacillus lignieresii
what is pathogenssis of the following lesion and dx from cow
- Bacteria enters soft tissue following trauma
- Extends to bone
- Pyogranulomatous osteomyelitis
Dx: lumpy jaw caused by actinomyces bovis
Cow tongue- what is pathogenesis of this lesion and dx
- Bacteria enter soft tissue from trauma
- Pyogranulomatous glossitis
Dx: wooden tongue caused by actinobacillus ligneresi
what dogs are predisposed to eosinophilic granuloma complex
Siberian huskies and KCCS
what is required to dx eosinophilic granuloma
biopsy
KCCS presents with these firm, ulcerated oral lesions- perform biopsy and see this- what is dx
eosinophilic granuloma complex’s
from cat- what dx
Chronic lymphoplasmacytic stomatitis
what are some causes of lymphoplasmacytic stomatitis
- Calicivirus
- FeLV
- FIV
What this and what breeds is most common in
gingival hyperplasia- most common in brachycephalics, especially boxers
What these and what cause
canine oral papillomas
Cause: canine papilloma virus
what is the most common malignant oral neoplasia of dogs
melanoma
what is most common malignant oral neoplasia of cats
SCC
what dx and prognosis
malignant melanoma- poor prognosis
from cat- what is dx
SCC
What dx and which breed is predisposed
Fibrosarcoma
Golden retrievers predisposed
what this
hyperdontia
What is pathogenesis of these lesions
Enamel hypoplasia
Ameloblast destruction—>decreased enamel production
what causes enamel hypoplasia in dogs and ruminants
dogs: distemper virus
Ruminants: excess fluoride
chronic dental disease can lead to what problems
suppurative periodontitis/ osteomyelitis—> tooth root abscess or oronasal fistulas
what is the most common tooth for tooth root abscesses
upper 4th premolar (carnassial tooth)
what this and what does it arise from
peripheral odontogenic fibromas- arise from periodontal ligament
tissue from ox. What would be your morphological diagnosis for lesion below and what are 5 differentials
Erosions and ulcers
1. FMD
2. BVDV
3. MCF
4. vesicular stomatitis
5. infectious bovine rhinotracheitis (BHV-1)