Lecture 22: Urinary Pathology 4 Flashcards

1
Q

What species does stephanurus dentatus infect

A

swine

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2
Q

what is pathogenesis of stephanurus dentatus

A
  1. Ingestion of larvae or infected earthworm or dermal penetration of larvae
  2. Larvae migrate from intestine—> liver—> kidney
  3. Adults in perirenal fat or in kidney
  4. Cyst communicates with renal pelvis or ureter
  5. Release eggs in urine
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3
Q

what are some associated lesions with stephanurus dentatus

A

milk spots/fibrosis on liver

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4
Q

what is a sequela of stephanurus dentatus

A

hydronephrosis

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5
Q

from pig- what likely cause

A

Stephanurus dentatus

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6
Q

what is dioctophyma renale known as

A

giant kidney worm

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7
Q

Who does dioctophyma renale affect

A

dog, mink, cat, any fish eating mammals

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8
Q

During necropsy of dog you find this in renal pelvis what wrong

A

dioctophyma renale

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9
Q

what is sequela of dioctophyma renale

A

adults in kidneys—> hemorrhagic to suppurative pyelitis—> ureteral obstruction—> parenchymal atrophy and hydronephrosis

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10
Q

what this and where are they found

A

Pearsonema spp- attach to urinary bladder mucosa> ureter and pelvis

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11
Q

t or f: no clinical signs of pearsonema spp

A

true

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12
Q

what is the most common primary renal tumor of dog, cattle, and horse

A

renal carcinoma

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13
Q

From dog what this

A

renal carcinoma

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14
Q

which species is metastasis common in for renal carcinomas

A

dogs, rarely cattle

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15
Q

what this and who is it common in

A

renal nephroblastoma
Common in pigs and chickens»> calves and dogs (GSD)

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16
Q

what does a nephroblastoma arise from

A

primitive renal tissue- true embryonal tumor

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17
Q

what is histo appearance of renal nephroblastoma

A

primitive glomeruli and tubules and primitive mesenchyme

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18
Q

renal nephroblastoma can produce __ that increases __

A

erythropoetin, increase RBC

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19
Q

renal nephroblastoma metastasis common in who and where

A

dogs- sublumbar LN, liver, lung

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20
Q

What is the most common renal neoplasm of cats and what is cause

A

lymphoma
Cause: FeLV

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21
Q

what is cause of lymphoma in cattle

A

BLV

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22
Q

From cat what wrong

A

Lymphoma

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23
Q

what is in lower urinary tract

A

ureter, urinary bladder and urethra

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24
Q

female or male: shorter tract predisposes to more infections

A

female

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25
Q

female or male: longer tract predisposes to more obstructions

A

male

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26
Q

what wrong and what cause

A

dilated urinary bladder
Cause: obstruction vs neuromuscular disease

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27
Q

what wrong and who is this common in

A

ruptured urinary bladder
Common in male newborn foals

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28
Q

what are causes of ruptured urinary bladder

A

urethral obstruction, trauma, dystocia

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29
Q

what is sequela to ruptured urinary bladder

A

uroperitoneum

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30
Q

how do you dx ruptured urinary bladder

A

see peritoneal effusion take serum ration of potassium, phosphorus and creatinine if it is >2:1 then urinary bladder rupture

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31
Q

where is the most common place of urolithiasis

32
Q

what species is urolithiasis most co mon in

A

cats, sheep/goats, dogs, cattle

33
Q

what species are matrix plugs commonly found in

34
Q

what stones do you get with acidic urine

35
Q

what stones do you get with alkaline urine

A

struvites: carbonate and phosphate

36
Q

what type of stone do you get with bacterial infection

37
Q

what is common location for urethral stone obstruction in dogs

A

base of os penis

38
Q

what is common location for urethral obstruction in cats

A

entire urethra

39
Q

what is common location for urethral obstruction in cattle

A

sigmoid flexure

40
Q

what is common location for urethral obstruction in sheep/goats

A

vermiform appendage

41
Q

what is common location for urethral obstruction in all animals

A

ischial arch

42
Q

what is the sequela or urolithiasis if stone in renal pelvis/ureter

A

hydronephrosis and pyelonephritis +/= rupture ureter—> hydroureter

43
Q

what is sequela if urolithiasis in urinary bladder

A

distended urinary bladder with thinned walls, inflamed bladder (cystitis)

44
Q

what is sequela of urolithiasis in urethra

A

urethral obstruction—> death from hyperkalemia

45
Q

what are some clinical signs of urolithiasis

A

dysuria, stranguria, pollakiuria, Hematuria, post renal azotemia

46
Q

What stone is this and who is it common in. When is it a problem

A

silica
Ruminants ingesting grasses rich in silica

Problem when urine production is low

47
Q

from dog what type of stone, what is it associated with

A

struvite
Associated with infections, especially canine females with alkaline urine

48
Q

from cat what kind of stone. What breeds common in and what risk factor

A

oxalate
Breeds: Persians and himalayans
Risks: acidic urine

49
Q

what stone is this. What is risk factor, what breed and what associated diseases

A

Urate
Risk: high protein diet
Breed: Dalmatians
Dz: liver disease, PSS

50
Q

cystitis more common in males or females

51
Q

what are some causes of cystitis in all animals, cattle, pigs

A

all: E.coli
Cattle: Cornybacterium renale and T. Pyogenes
Pig: actinobaculum suis

52
Q

what wrong

53
Q

what is most common cause of feline lower urinary tract disease

A

idiopathic

54
Q

what are some predisposes factors to cystitis

A
  1. Urine stasis
  2. Hooded vulva
  3. Urinary incontinence
55
Q

what wrong

A

Cystitis, hemorrhagic cystitis

56
Q

what is polyploid cystitis

A

chronic cystitis inflammation and hyperplasia

57
Q

polyploid cystitis is associated with __ or __

A

persistent UTI or urolithiasis

58
Q

what Is follicular cystitis

A

chronic cystitis with lymphoid follicle formation

59
Q

what is cause of follicular cystitis

A

chronic urolithiasis

60
Q

dog bladder what wrong

A

polyploid cystitis

61
Q

dog bladder what wrong

A

Follicular cystitis

62
Q

what is cause of emphysematous cystitis

A

gas producing bacteria cause gas expansion of bladder wall

63
Q

what disease is emphysematous cystitis typically associated with

A

DM-glucosuria

64
Q

what wrong

A

emphysematous cystitis

65
Q

what does ingestion of bracken fern cause

A

enzootic Hematuria in cattle

66
Q

what is pathogenesis of enzootic Hematuria in cattle

A
  1. Ingestion of bracken fern
  2. Lesions of inflammation, hyperplasia, metaplasia, dysplasia
  3. Increased amount of time develop into multiple types of tumors
67
Q

what tumors are associated with enzootic Hematuria

A

papillomas, fibromas, hemangioma, carcinoma

68
Q

cow bladder- what wrong and what cause

A

hemangioma
Cause: enzootic Hematuria from bracken fern

69
Q

where is the most common site for primary epithelial neoplasia in lower urinary tract

70
Q

what this and what causing

A

TCC—> hydronephrosis

71
Q

what is sequela to TCC

A

obstruction—> hydroureter, hydronephrosis, metastasis to sublumbar LN

72
Q

What wrong

A

rhabdomyosarcoma causing hypertrophic osteopathy

73
Q

what is origin of botryoid rhabomyosarcoma

A

embryonal myoblasts

74
Q

who gets botytroid rhabdomyosarcoma

A

young, <2yrs, large breed dogs- Saint Bernards

75
Q

what is an associated lesion of botryoid rhabdomyosarcoma

A

hypertrophic osteopathy