Lecture 22: Urinary Pathology 4 Flashcards
What species does stephanurus dentatus infect
swine
what is pathogenesis of stephanurus dentatus
- Ingestion of larvae or infected earthworm or dermal penetration of larvae
- Larvae migrate from intestine—> liver—> kidney
- Adults in perirenal fat or in kidney
- Cyst communicates with renal pelvis or ureter
- Release eggs in urine
what are some associated lesions with stephanurus dentatus
milk spots/fibrosis on liver
what is a sequela of stephanurus dentatus
hydronephrosis
from pig- what likely cause
Stephanurus dentatus
what is dioctophyma renale known as
giant kidney worm
Who does dioctophyma renale affect
dog, mink, cat, any fish eating mammals
During necropsy of dog you find this in renal pelvis what wrong
dioctophyma renale
what is sequela of dioctophyma renale
adults in kidneys—> hemorrhagic to suppurative pyelitis—> ureteral obstruction—> parenchymal atrophy and hydronephrosis
what this and where are they found
Pearsonema spp- attach to urinary bladder mucosa> ureter and pelvis
t or f: no clinical signs of pearsonema spp
true
what is the most common primary renal tumor of dog, cattle, and horse
renal carcinoma
From dog what this
renal carcinoma
which species is metastasis common in for renal carcinomas
dogs, rarely cattle
what this and who is it common in
renal nephroblastoma
Common in pigs and chickens»> calves and dogs (GSD)
what does a nephroblastoma arise from
primitive renal tissue- true embryonal tumor
what is histo appearance of renal nephroblastoma
primitive glomeruli and tubules and primitive mesenchyme
renal nephroblastoma can produce __ that increases __
erythropoetin, increase RBC
renal nephroblastoma metastasis common in who and where
dogs- sublumbar LN, liver, lung
What is the most common renal neoplasm of cats and what is cause
lymphoma
Cause: FeLV
what is cause of lymphoma in cattle
BLV
From cat what wrong
Lymphoma
what is in lower urinary tract
ureter, urinary bladder and urethra
female or male: shorter tract predisposes to more infections
female
female or male: longer tract predisposes to more obstructions
male
what wrong and what cause
dilated urinary bladder
Cause: obstruction vs neuromuscular disease
what wrong and who is this common in
ruptured urinary bladder
Common in male newborn foals
what are causes of ruptured urinary bladder
urethral obstruction, trauma, dystocia
what is sequela to ruptured urinary bladder
uroperitoneum
how do you dx ruptured urinary bladder
see peritoneal effusion take serum ration of potassium, phosphorus and creatinine if it is >2:1 then urinary bladder rupture
where is the most common place of urolithiasis
ureter
what species is urolithiasis most co mon in
cats, sheep/goats, dogs, cattle
what species are matrix plugs commonly found in
male cats
what stones do you get with acidic urine
oxalate
what stones do you get with alkaline urine
struvites: carbonate and phosphate
what type of stone do you get with bacterial infection
struvite
what is common location for urethral stone obstruction in dogs
base of os penis
what is common location for urethral obstruction in cats
entire urethra
what is common location for urethral obstruction in cattle
sigmoid flexure
what is common location for urethral obstruction in sheep/goats
vermiform appendage
what is common location for urethral obstruction in all animals
ischial arch
what is the sequela or urolithiasis if stone in renal pelvis/ureter
hydronephrosis and pyelonephritis +/= rupture ureter—> hydroureter
what is sequela if urolithiasis in urinary bladder
distended urinary bladder with thinned walls, inflamed bladder (cystitis)
what is sequela of urolithiasis in urethra
urethral obstruction—> death from hyperkalemia
what are some clinical signs of urolithiasis
dysuria, stranguria, pollakiuria, Hematuria, post renal azotemia
What stone is this and who is it common in. When is it a problem
silica
Ruminants ingesting grasses rich in silica
Problem when urine production is low
from dog what type of stone, what is it associated with
struvite
Associated with infections, especially canine females with alkaline urine
from cat what kind of stone. What breeds common in and what risk factor
oxalate
Breeds: Persians and himalayans
Risks: acidic urine
what stone is this. What is risk factor, what breed and what associated diseases
Urate
Risk: high protein diet
Breed: Dalmatians
Dz: liver disease, PSS
cystitis more common in males or females
females
what are some causes of cystitis in all animals, cattle, pigs
all: E.coli
Cattle: Cornybacterium renale and T. Pyogenes
Pig: actinobaculum suis
what wrong
cystiti
what is most common cause of feline lower urinary tract disease
idiopathic
what are some predisposes factors to cystitis
- Urine stasis
- Hooded vulva
- Urinary incontinence
what wrong
Cystitis, hemorrhagic cystitis
what is polyploid cystitis
chronic cystitis inflammation and hyperplasia
polyploid cystitis is associated with __ or __
persistent UTI or urolithiasis
what Is follicular cystitis
chronic cystitis with lymphoid follicle formation
what is cause of follicular cystitis
chronic urolithiasis
dog bladder what wrong
polyploid cystitis
dog bladder what wrong
Follicular cystitis
what is cause of emphysematous cystitis
gas producing bacteria cause gas expansion of bladder wall
what disease is emphysematous cystitis typically associated with
DM-glucosuria
what wrong
emphysematous cystitis
what does ingestion of bracken fern cause
enzootic Hematuria in cattle
what is pathogenesis of enzootic Hematuria in cattle
- Ingestion of bracken fern
- Lesions of inflammation, hyperplasia, metaplasia, dysplasia
- Increased amount of time develop into multiple types of tumors
what tumors are associated with enzootic Hematuria
papillomas, fibromas, hemangioma, carcinoma
cow bladder- what wrong and what cause
hemangioma
Cause: enzootic Hematuria from bracken fern
where is the most common site for primary epithelial neoplasia in lower urinary tract
bladder
what this and what causing
TCC—> hydronephrosis
what is sequela to TCC
obstruction—> hydroureter, hydronephrosis, metastasis to sublumbar LN
What wrong
rhabdomyosarcoma causing hypertrophic osteopathy
what is origin of botryoid rhabomyosarcoma
embryonal myoblasts
who gets botytroid rhabdomyosarcoma
young, <2yrs, large breed dogs- Saint Bernards
what is an associated lesion of botryoid rhabdomyosarcoma
hypertrophic osteopathy