lecture 8 Flashcards

1
Q

Arterial blood flows in which direction?

A

Arterial blood flows away from the heart

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2
Q

Venous blood flows in which direction?

A

Venous blood flows toward the heart

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3
Q

Which contracts first atria ventricles?

A

Atria

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4
Q

Tricuspid and mitral valves control flow between?

A

the atria and ventricles

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5
Q

Aortic and pulmonary control flow from?

A

the ventricles out to the circulatory vessels

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6
Q

How many myocytes are activated during each heart beat?

A

Every myocyte is activated

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7
Q

How can you increase force of a cardiac contraction?

A

Increase cystolic Ca2+ level
increase number of cross-bridges formed
increase force of contraction

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8
Q

Cellular mechanism of cardiac relaxation?

A

Decrease in cystolic Ca2+ levels, pumped back into sarcoplasmic reticulum
ATP binds to myosin to release cross bridges
All cardiomyocytes relax

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9
Q

What is the name of the circuit that sends oxygen-rich blood back to the tissues of the body and brings oxygen-poor blood back to the heart?

A

Systemic circuit

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10
Q

Which circuit has the least resistance?

A

pulmonary circuit

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11
Q

Q=P/R

A

flow = pressure difference / resistance

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12
Q

Which circuit has a higher arterial pressure?

A

Systemic

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13
Q

High blood pressure is called?

A

Hypertension

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14
Q

Low blood pressure is called?

A

Hypotension

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15
Q

Diastole is when?

A

Heart muscle relaxes and the chambers of the heart fill with blood, blood pressure decreases.
the mitral and tricuspid valves are open

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16
Q

Systole is when?

A

Period of contraction of the ventricles of the heart and blood is ejected into the aorta and pulmonary trunk

17
Q

CO2 is removed at the?

A

Pulmonary capillaries

18
Q

Deoxygenated blood from the systemic circulation drains from?

A

The superior and inferior vena cava into the right atrium -> right ventricle -> pulmonary trunk -> pulmonary arteries -> lungs

19
Q

Oxygenated blood travels from?

A

The lungs in the pulmonary veins -> left atrium -> left ventricle -> aorta -> periphery

20
Q

How are cardiomyocytes connected physically?

A

Intercalated discs

21
Q

Which junctions help for better spread of calcium?

A

Gap junctions directly connect cells cytoplasm which allows currents to move between adjacent cells

22
Q

The direct connection between cardiac cells allow?

A

The heart to pump as a functional synctium

23
Q

what are the key phases of the cardiac cycle?

A
Atrial systole 
isovolumetric contricular contraction
ventricular ejection
Isovolumetricular ejection 
Ventricular diastole
24
Q

During which phase of the cardiac cycle is the largest spike in pressure?

A

Isovolumetric contraction

25
Q

What does isovolumetric mean?

A

The valves are closed so there is no gain or loss of blood but the heart is contracting or relaxing

26
Q

What is pulse pressure?

A

The difference between systolic and diastolic pressure

27
Q

What are systolic and diastolic pressure?

A

systolic is the highest point of the systole phase and diastolic is the lowest point of diastole phase

28
Q

Which valves are open and/or closed during atrial systole?

A

Av valves are open and the ventricle and atria are filling but the semilunar valves are closed

29
Q

Which valves are open or closed during isovolumetric contraction?

A

Av valves and semilunar valves are closed and the ventricles are contracting

30
Q

Which valves are open or closed during ventricular ejection?

A

Semilunar valves are open, Av valves are closed

31
Q

Which valves are open or closed during isovolumetric contricular relaxation?

A

Semilunar and AV valves are shut

32
Q

Which valves are open or closed during passive filling?

A

AV valves are open but semilunar valves are closed.

33
Q

What causes the aortic valves to open?

A

When the ventricular pressure exceeds the aortic pressure

34
Q

Which phase of the cardiac cycle has the biggest pressure spike?

A

Isovolumetric contraction

35
Q

Name the 5 phases of the cardiac cycle?

A
Atrial systole 
Isovolumetric contraction 
Ventricular ejection 
isovolumetric contricular relaxation 
ventricular diastole