lecture 12 Flashcards

1
Q

What has the greatest distribution of blood?

A

Veins, in particularly veins and venules

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2
Q

Why do veins have the greatest distribution of blood?

A

They have the ability of act as capacitance vessels and is stored at a low pressure

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3
Q

What percentage of the blood is systemic venous system?

A

64%

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4
Q

How do veins store more blood at a lower pressure?

A

Thin walls = more compliance

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5
Q

compliance =?

A

change in volume / change in pressure

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6
Q

A small change in volume in veins =

A

large change in pressure

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7
Q

A small change in volume in arteries =?

A

large change in pressure

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8
Q

What is starling’s law of the heart?

A

The more stretched the muscle fibres are before a contraction, the stronger the contraction will be

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9
Q

what is compliance?

A

the extent to which a vessel allows deformation in response to changes in pressure

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10
Q

What do veins do in response to major blood loss?

A

Vasoconstrict to cause an increase in blood arterial circulation

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11
Q

In an upright position where does the increase in venous volume go?

A

below the heart due to gravity

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12
Q

What are the two ways to counteract venous pooling when standing?

A

Venous valves

skeletal muscle

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13
Q

What are venous valves?

A

valves that counteract the pooling and prevent blood flow back down the legs

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14
Q

How does skeletal muscle counteract venous pooling

A

the muscle tone stiffens veins to make them less compliant and less prone to pooling

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15
Q

What increases the preload on the heart?

A

venous return

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16
Q

What does preload do?

A

more stretch on the heart

17
Q

What causes an increase in left ventricular end diastolic pressure?

A

Venous return

18
Q

What happens when cardiomyocytes become too stretched?

A

cardiac performance starts to decrease

19
Q

What is the total blood volume in a 70kg human?

A

approx 5L

20
Q

Which way does the pressure gradient for blood run?

A

Arteries (high pressure), veins (low pressure)

21
Q

What do skeletal muscle contractions do?

A

Increase venous return