Lecture 10 Flashcards

1
Q

All body processes directly or indirectly require ATP
- Most ATP synthesis requires _________ and produces ______________
- This drives the need to __________
-taking in ________
-eliminating __________

A
  • oxygen; carbon dioxide
  • breathe
    -oxygen
    -carbon dioxide
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2
Q

Functions of the Respiratory System
1.
2.
3.
4.
5.
6.
7.
8.
9.

A
  1. gas exchange
  2. Communication
  3. Olfaction
  4. Acid-Base balance
  5. Blood pressure regulation (ACE- angiotensin converting enzyme)
  6. Blood and lymph flow (thoracic pump)
  7. Platelet production (more than 1/2 produced by megakaro’s in the lungs)
  8. Blood filtration (of small blood clots)
  9. Expulsion of abdominal contents
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3
Q

Anatomy of the Respiratory System
Principal Organs:
- ___________
- ___________
- ___________
- ___________
- ___________
- ___________

A
  • nose
  • pharynx
  • larynx
  • trachea
  • bronchi
  • lungs
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4
Q

Organs of upper respiratory tract (in the ______ and _______)
1.
2.
3.

A

head; neck
1. nose
2. pharynx
3. larynx

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5
Q

Organs of the lower respiratory tract (in the ________ _________)
1.
2.
3.
4.

A

thoracic cavity
1. trachea
2. lungs
3. bronchi
4. alveoli

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6
Q

___________ zone of respiratory system
- includes those passages that serve only for ______
- NO gas exchange
- _________ through major _____________

_______________ zone of the respiratory system
- consists of ________ and other gas exchange regions

A

Conducting
- airflow
- nostrils; bronchioles (passages are too thick for adequate diffusion)

Respiratory
- alveoli

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7
Q

The Trachea
- also called the __________
- ___________ to esophagus
- supported by ___________ cartilage
- lined by _____________ ___________ epithelium
- ________-________ ________ cells

A
  • windpipe
  • anterior
  • hyaline
  • pseudostratified columnar (ciliated)
  • mucous-secreting goblet
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8
Q
  • The larynx consists of ________ cartilage and inferior to that is ______ cartilage (full ring)
  • the trachea consists of __________ cartilage in half circle rings; __________ is in between both ends of the ring
  • the trachea also has a _________ __________ where debris can be pushed up to the pharynx
A
  • thyroid; cricoid
  • hyaline; trachealis
  • mucociliary escalator
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9
Q

Bronchi
- lined by _________ _________ epithelium (_______)
- ________-___________
- _________ __________ layer to constrict and dilate airway

Bronchioles
- lined by _________ _________ epithelium
- _________ __________

Terminal Bronchioles (#_________)
- no _________
- have _______

A
  • pseudostratified columnar (ciliated)
  • mucous-secreting
  • smooth muscle
  • ciliated cuboidal
  • smooth muscle
  • 65,000
  • mucus
  • cilia
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10
Q

Cells of the Alveolus
- ____________(________) alveolar cells: cover ____% of alveolar surface area
- ___________(________) alveolar cells: secrete _________; core ___% of alveolar surface
- alveolar ___________ (____ cells): most __________ cells in the lungs

A
  • squamous (type I); 95
  • great (type II); surfactant; 5
  • macrophages (dust); numerous
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11
Q

Alveolar Pressure/Exchange
- _______ in lungs can be fatal
-gasses would diffuse too slowly to aerate blood
- To prevent _______ accumulation:
-alveoli kept dry by _____ pressure in __________ end capillaries–10 mmHg (30mmHg in other tissues)
-___________ overrides __________, no excess fluid in capillary
- ________ have more extensive lymphatic drainage than any other organ in the body

A
  • fluid
  • fluid
    -low; arteriole
    -reabsorption; filtration
  • lungs
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12
Q

_____________: thin barrier between alveolar air and blood
- Consists of three layers:
1.
2.
3.
- ____ um thick (1/15 diameter of RBC)

A

Respiratory membrane
1. squamous alveolar cells
2. endothelial cells of blood capillary
3. their shared basement membrane
- 0.5

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13
Q

The Pleurae
- ___________ pleura: serous membrane (touches the lungs)
- __________ pleura: adheres to mediastinum
- ___________ ________: potential space; contains a film of slippery pleural fluid

A
  • visceral
  • parietal
  • pleural cavity
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14
Q

Breathing= ________________
- ___________ (inhaling)
- ___________ (exhaling)
- ___________ _______ one complete cycle of inhaling and exhaling
- ______ ____________: breathing while at rest, effortless, and ________
- ________ __________: deep, rapid breathing, such as during _________

A

pulmonary ventilation
- inspiration
- expiration
- respiratory cycle
- quiet respiration; automatic
- forced respiration; exercise

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15
Q

The Respiratory Muscles
During inspiration:
- _______ __________ (elevate ribs __-___, _____ thoracic cavity)
- ______________ (________ and ______; ________ depth of thoracic cavity)

During FORCED expiration:
- ____________ _________ (depress ribs __-____, _______ thoracic cavity)
- _____________ (________ and ______; ________ depth of thoracic cavity )

A
  • external intercostals (2-12; widen)
  • diaphragm (descends; flattens; increasing)
  • internal intercostals (1-11; narrow)
  • diaphragm (ascend; round; decreasing)
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16
Q

__________ ___________: breathing technique used to help expel contents of certain ________ organs
- depression of the ________ raises abdominal pressure
- consists of taking a deep breath ___, holding it by closing the ______, and then contracting the __________ muscles
-aids in ________, __________, _________, ________

A

valsalva maneuver; abdominal
- diaphragm
- IN; glottis; abdominal
-childbirth; urination; defecation; vomiting

17
Q

Neural control of Breathing
- Breathing depends on repetitive stimulation of _______ ________ from brain and will cease if spinal cord is severed high in _______
- Breathing is controlled at two levels of the brain
1. ________ and _________
2. _________ and _________

A
  • skeletal muscle; neck
    1. cerebral; conscious
    2. unconscious; automatic
18
Q

Respiratory Control Centers in the CNS
- ___________________: primary generator of the respiratory rhythm
-produces a respiratory rhythm of ____ breaths per minute

-___________________: modifies the rate and depth of breathing
-receives influences from _________ sources

-____________________: modifies ryhtym
-adapts to ______, _______, _________…..

A
  • ventral respiratory group (VRG)
    -12
  • dorsal respiratory group (DRG)
    -external
  • Pons (pontine) respiratory group (PRG)
    -sleep; emotion; exercise
19
Q

_______ __________ ________: brainstem neurons that respond to changes in pH of cerebrospinal fluid
- regulate respiration to maintain stable pH

A

central chemoreceptor neurons

20
Q

Respiratory Control
Also supplying sensory input to respiratory centers are……
- _____________ ___________ (carotid bodies; aortic bodies): respond to O2 and CO2 content of blood
- ___________ ___________ in smooth muscles of bronchi and bronchioles and in visceral pleura that respond to inflation of the lungs
- __________ __________ nerve endings amid epithelial cells in the airway

A
  • peripheral chemoreceptors
  • stretch receptors
  • irritant receptors
21
Q

_____________: anxiety-triggered state in which breathing is so rapid that it expels _____ from the body faster than it is produces
- as blood ______ levels drop, the pH ______ causing the cerebral arteries to ________
- this reduces cerebral __________ which may cause dizziness or fainting

  • can be brought under control by having the person rebreathe the expired ______ from a paper bag
A

hyperventilation; CO2
- CO2; rises; constrict
- perfusion
- CO2

22
Q

Voluntary control over breathing originates in the ______ ______ of the _______ lobe of the cerebrum
- sends impulses down the ____________ tracts to respiratory neurons in spinal cord, bypassing brainstem

Limits to voluntary control
- breaking point: when _____ levels rise to a point where ___________ control override one’s will

A

motor cortex; frontal
- corticospinal
- CO2; automatic