last Q 2 Flashcards
O2 content of arterial supply
200 mL / L blood
O2 content of venous supply
150 mL / L blood
what mechanosm do we use in autoregulation?
Bayliss effect
dilating or constravting vessels with myogenic tone
Laplack law
tension = pressure X radius
mechanism of local controll includes
autoregulation
metabloic regulation
endothelial mediated
which structures dont have sympathetic innervation at all so only local controll
precapillary spinchters
higher buils up of metabolic waste will cause vasodilation -> increased blood flow to wash this substrates
functional hyperemia will happen when
if cell function increase -> metabolism increase -> metabolites increase ->vasodilation -> blood flow increase
reactive hyperemia will happen when
increase in flow aftera a period of decreased blood flow
when flow is blocked, metabolites build up and cause vasodilation so after the flow returns much much biggerrrr
how NO causes vasodilation?
cGMP increased will activate cGMP protein kinase that will lead to vasodilation
humoral vasoconstrictors
endothelin
Ang-II