5.3 Flashcards
Salivary acinar cells secrete
H2O Electrolytes a-amylase Lingual Lipase Mucus IgA Kallikrein
What is the job of Kallikrein?
cleaves High Molecular Weight Kininogen into Bradykinin (Vasodilator)
What happens to the saliva composition in high flow rate and why?
final saliva most closely resembels plasma bcs it has no time to be in contact with the ductal cells- flow is very fast!!
What happens to the saliva composition in low flow rate and why?
final saliva most dissimilar to plasma bcs it has a lot of time to spend near ductul cells which will alter its composition!
Describe HCO3- concentration of Saliva
low at the lowest flow rate and highest at high flow rate
Bcs. HCO3- secretion is selectively stimulated when saliva production is stimulated
LES+ Cardia secrete
Mucus
HCO3-
fundus+ Body secrete
H+ Intrinsic Factors Pepsinogen Lipase Mucus HCO3-
Antrum+ Pylorus secrete
Mucus
HCO3-
fundus+ Body Motility
Tonic force during emptying
Antrum+ Pylorus Motility
mixing
grinding
sieving
regulation of emptying
what stimulates Parietal cell secretion?
ACh
Gastrin
Histamine
location of stomach secretion cells
parietal cells- Body
chief cells- Body
G cells- Antrum
Mucous cells- Antrum
stomach secretion cells- what do they secrete?
parietal cells- IF, HCl
chief cells- Pepsinogen
G cells- Gastrin to circulation
Mucous cells- Mucous
What inhibits the release of Gastrin from G cells?
D cells sense high H+ conc in the antrum -> release SST -> inhibit G cells
surface of the stomach is protected by?
gastric mucosal barrier
