5.6 Flashcards

1
Q

Metabolism refers to

A

Chemical reactions in the body

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2
Q

1 calorie= ___ J

A

4.2 Joules

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3
Q

How do we measure the amount of energy food provides?

A

Calorimeter- burns food

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4
Q

energy content of carbohydrates

A

17.2 kJ/gram

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5
Q

energy content of proteins

A

17.2 kJ/gram

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6
Q

respiratory quotient (RQ) is the ratio:

A

RQ = CO2 eliminated / O2 consumed

for each nutrient the metabolism is different

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7
Q

energy content of fat

A

39 KJ/gram

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8
Q

RQ for carbohydrates

A

1

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9
Q

RQ for proteins

A

0.82

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10
Q

RQ for fat

A

0.7

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11
Q

How can we measure TEE?

A

measuring a personws heat production (=rate of metabolism)

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12
Q

TEE=

A

heat production + external work

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13
Q

What is the indirect method of measuring TEE?

A

we measure oxygen consumption

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14
Q

Define BMR

A

minimal energy expenditure required to exist

awake, without physical activity

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15
Q

TEE=

A

BMR + DIT + EE in physcial activity

Diet Induced Thermogenesis

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16
Q

How do we measure BMR?

A
  • usually in the morning
  • no physical activity
  • 20 C
  • no food
  • no stress
  • no drugs
17
Q

Normal BMR values

A
Men= 7,000 KJ/day
Women= 6,000 KJ/day
18
Q

BMR is influenced by

A
  • body size
  • sex
  • age
  • temparture
  • climate
  • pregnancy
  • some hormones
  • drugs, stress, injuries
19
Q

BMR is how much of TEE?

A

usually 50-70%

20
Q

DIT is how much of TEE?

21
Q

EE in physical activity is how much of TEE?

22
Q

Brown adipose structure?

A

less fat

a lot of mitochondria

23
Q

What is the special feature of brown adipocyte?

A

their mitochondria contains Uncouplin Protein (UCP1)

24
Q

UCP1 effect?

A

allows H+ to flow from intermembrane space to matrix

leading to less ATP synthesis and more heat production

25
What does stimulation of B3 R on brown adipocytes lead to?
Gs Hormone sensitive Lipase activation TAG cleavage free FA activate UCP1
26
What will stimulate the baige adipose tissue?
exposure to cold and to catecholamines
27
feeding center and satiety center get info from
arcuate nucleus
28
POMC
Pro Opio Melano Cortin
29
Anorexigenic neurons release
POMC -> decreased appetite
30
Orexigenic neurons release
Neuropeptide Y -> increased appetite
31
effects of leptin
- decreased hunger (stimulate anorexigenic neurons) - increased thermogenesis - increased energy expenditure so overall to restore adipose tissue mass to set point
32
Neuropeptides from GI that will decrease hunger?
- GLP1 (stimulates insulin secretion) - Peptide YY (inhibits ghrelin) - CCK (Chylocystokinin) - CART (Cocaine-And-Amphetamine-Regulated-Transcript)
33
Neuropeptides from GI that will increase hunger?
- Ghrelin (GHRH) | - Orexins (fight against sleep)