lab 6 bones Flashcards
where bone and marrow replace a preexisting hyaline cartilage template or anlagen of future bone
Endochondral ossification (EO)
where bone is deposited directly within primitive connective tissue or mesenchyme
Intramembranous ossification (IO)
two type of bone formation
Intramembranous ossification (IO) Endochondral ossification (EO),
In both cases, a primary or immature bone is first laid down, and is then transformed (“remodeled”) into ____bone.
mature
EO makes ___ bone
Cancellous
spongy
trabecular
IO makes ___ bone
Compact
dense
cortical (periosteal)
___ bone is designed for a supportive and weight- bearing role.
compact
dense
cortical
What kind of bone is web-like and porous, is surrounded by bone marrow, and likely provides appropriate niches for blood cell development in the marrow cavity?
EO bone
Cancellous (also called spongy or trabecular)
ECM on bone
type 1 collagen
amorphous ground substance: small, non-sulfated proteoglycans
ECM mineralized, very hard
the calcium salts of the ECM of bone are in the form of crystals called ____
hydroxyapatites.
bone cells
osteocytes
__ bone is found in such regions as the shaft of long bones, and many cranial bones.
compact
IO bone
IO bone main function is
supportive and weight-bearing role
basic unit of compact bone
osteon (haversian system)
concentric rings of bone ECM are called
lamellae
central canal of an osteon
Haversian Canal
Small, concentrically arrayed holes surrounding the Haversian canal represent ___
osteocyte lacunae.
tiny projections resembling spider webs radiate from the lacunae are ___
canaliculi
in life Haversian Canal’s contain ___
blood vessels, nerves and areolar connective tissue
fine cell processes of osteocytes to allow them to interact with each other
filopodia
Haversian canals run parallel to the long axis of the bone. They are interconnected by transverse or oblique canals called ___
Volkmann Canal
the space in between osteons are ___
interstitial lamellae, old bone/old osteons that have been partially removed
cancellous bone is derived by ___
EO
cancellous, spongy, trabecular
This term is applied when bone development occurs directly within or below a connective tissue membrane.
Intramembranous Ossification
Most flat bones, e.g., frontal, parietal, dentary and maxilla, arise by ___
Intramembranous Ossification
explain IO formation
Within the mesenchyme (connective tissue membrane) of the embryo where a flat bone is to appear, osteoblasts will secrete bone matrix in the form of spicules.
These enlarge into trabeculae (slightly larger than spicules), which fuse together, forming a 3-D latticework as the bone grows and develops to its final size and form
The layer of pale matrix that is seen lining the spicules of IO bone; this ECM is still uncalcified and is called ____
osteoid
- Haversian canal
- Haversian canal connecting to a Volkmann’s canal
- Osteocyte lacuna
- Interstitial lamellae
- Osteon
Compact bone
- Concentric lamellae
- Haversian canal
- Canaliculi
- Interstitial lamellae
- Osteocyte lacuna
- Tendon
- Periosteum
- Compact bone
- Marrow cavity
- Tendon
- Periosteum
- Haversian canal
- Osteocytes
Sternebra
- Compact bone
- Trabecular bone
- Bone marrow cavity
- Potential Fibrocartilage
- Future Costal Cartilage
- Muscle
- Bone and Bone Marrow
EO
- Zone of proliferation (zone of multiplication)
- Zone of hypertrophy
- Zone of degradation (zone of calcification)
- Zone of ossification
- Intramembranous bone
- Intramembranous bone
2. Osteoblasts
- Intramembranous bone
2. Osteoblasts
compact bone
what is this
label
what is the weird shaped area?
interstitial lamella
what are the white spaces?
What is the arrow pointing to?
Haversian Canals (longitudinal) osteocyte in a lacunae
arrows?
top arrow osteocyte (bone cell)
bottom arrow osteoclast (eat bone)
white space- bone marrow with red blood cells
what is the blue
what is the white
what is the pink
blue bone
white bone marrow and red blood cells
pink osteoclasts (eat bone, multinucleated)
what is this?
what are the arrows?
what is the ball on the right?
developing membrane bone (spincule)
osteoblast (make bone)
young hypercellular cartilage)
arrows?
blue: harversion canal
purple: lacunae
green: osteocyte
the pale purple part?
the pink part?
the spotted part?
pale purple is cartilage back bone
pink part: new bone
spotted: marrow and red blood cells
osteoclast: multinucleated, pink eating bone
whole in center
long hole?
haversian canal
volkmans canal
IO bone being formed
pink is bone
osteoblasts surround bone
