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21 fall: histology > lab 6 bones > Flashcards

lab 6 bones Flashcards

1
Q

where bone and marrow replace a preexisting hyaline cartilage template or anlagen of future bone

A

Endochondral ossification (EO)

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2
Q

where bone is deposited directly within primitive connective tissue or mesenchyme

A

Intramembranous ossification (IO)

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3
Q

two type of bone formation

A 
Intramembranous ossification (IO)
Endochondral ossification (EO),
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4
Q

In both cases, a primary or immature bone is first laid down, and is then transformed (“remodeled”) into ____bone.

A

mature

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5
Q

EO makes ___ bone

A

Cancellous
spongy
trabecular

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6
Q

IO makes ___ bone

A

Compact
dense
cortical (periosteal)

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7
Q

___ bone is designed for a supportive and weight- bearing role.

A

compact
dense
cortical

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8
Q

What kind of bone is web-like and porous, is surrounded by bone marrow, and likely provides appropriate niches for blood cell development in the marrow cavity?

A

EO bone

Cancellous (also called spongy or trabecular)

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9
Q

ECM on bone

A

type 1 collagen
amorphous ground substance: small, non-sulfated proteoglycans

ECM mineralized, very hard

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10
Q

the calcium salts of the ECM of bone are in the form of crystals called ____

A

hydroxyapatites.

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11
Q

bone cells

A

osteocytes

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12
Q

__ bone is found in such regions as the shaft of long bones, and many cranial bones.

A

compact

IO bone

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13
Q

IO bone main function is

A

supportive and weight-bearing role

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14
Q

basic unit of compact bone

A

osteon (haversian system)

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15
Q

concentric rings of bone ECM are called

A

lamellae

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16
Q

central canal of an osteon

A

Haversian Canal

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17
Q

Small, concentrically arrayed holes surrounding the Haversian canal represent ___

A

osteocyte lacunae.

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18
Q

tiny projections resembling spider webs radiate from the lacunae are ___

A

canaliculi

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19
Q

in life Haversian Canal’s contain ___

A

blood vessels, nerves and areolar connective tissue

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20
Q

fine cell processes of osteocytes to allow them to interact with each other

A

filopodia

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21
Q

Haversian canals run parallel to the long axis of the bone. They are interconnected by transverse or oblique canals called ___

A

Volkmann Canal

22
Q

the space in between osteons are ___

A

interstitial lamellae, old bone/old osteons that have been partially removed

23
Q

cancellous bone is derived by ___

A

EO

cancellous, spongy, trabecular

24
Q

This term is applied when bone development occurs directly within or below a connective tissue membrane.

A

Intramembranous Ossification

25
Q

Most flat bones, e.g., frontal, parietal, dentary and maxilla, arise by ___

A

Intramembranous Ossification

26
Q

explain IO formation

A

Within the mesenchyme (connective tissue membrane) of the embryo where a flat bone is to appear, osteoblasts will secrete bone matrix in the form of spicules.

These enlarge into trabeculae (slightly larger than spicules), which fuse together, forming a 3-D latticework as the bone grows and develops to its final size and form

27
Q

The layer of pale matrix that is seen lining the spicules of IO bone; this ECM is still uncalcified and is called ____

A

osteoid

28
Q
A
  1. Haversian canal
  2. Haversian canal connecting to a Volkmann’s canal
  3. Osteocyte lacuna
  4. Interstitial lamellae
  5. Osteon
29
Q
A

Compact bone

  1. Concentric lamellae
  2. Haversian canal
  3. Canaliculi
  4. Interstitial lamellae
  5. Osteocyte lacuna
30
Q
A
  1. Tendon
  2. Periosteum
  3. Compact bone
  4. Marrow cavity
31
Q
A
  1. Tendon
  2. Periosteum
  3. Haversian canal
  4. Osteocytes
32
Q
A

Sternebra

  1. Compact bone
  2. Trabecular bone
  3. Bone marrow cavity
  4. Potential Fibrocartilage
  5. Future Costal Cartilage
  6. Muscle
  7. Bone and Bone Marrow
33
Q
A

EO

  1. Zone of proliferation (zone of multiplication)
  2. Zone of hypertrophy
  3. Zone of degradation (zone of calcification)
  4. Zone of ossification
34
Q
A
  1. Intramembranous bone
35
Q
A
  1. Intramembranous bone

2. Osteoblasts

36
Q
A
  1. Intramembranous bone

2. Osteoblasts

37
Q

compact bone

A
38
Q

what is this

A
39
Q

label

A
40
Q

what is the weird shaped area?

A

interstitial lamella

41
Q

what are the white spaces?

What is the arrow pointing to?

A 
Haversian Canals (longitudinal)
osteocyte in a lacunae
42
Q

arrows?

A

top arrow osteocyte (bone cell)
bottom arrow osteoclast (eat bone)
white space- bone marrow with red blood cells

43
Q

what is the blue
what is the white
what is the pink

A

blue bone
white bone marrow and red blood cells
pink osteoclasts (eat bone, multinucleated)

44
Q

what is this?

A
45
Q

what are the arrows?

what is the ball on the right?

A

developing membrane bone (spincule)
osteoblast (make bone)
young hypercellular cartilage)

46
Q

arrows?

A
47
Q
A

blue: harversion canal
purple: lacunae
green: osteocyte

48
Q

the pale purple part?
the pink part?
the spotted part?

A

pale purple is cartilage back bone
pink part: new bone
spotted: marrow and red blood cells

49
Q
A

osteoclast: multinucleated, pink eating bone

50
Q

whole in center

long hole?

A

haversian canal

volkmans canal

51
Q
A

IO bone being formed
pink is bone
osteoblasts surround bone

21 fall: histology (36 decks)

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