L69. Neoplasia 1 Flashcards
What does “neoplasm” mean?
new growth
Describe the 2 neoplasm classifications.
- behavioural - benign or malignant
2. Histogenesis - epithelial, connective tissue or other
What is the growth pattern and spread of a benign tumour?
It expands in its area of origin and can press on other tissues.
Describe the growth and spread of a malignant tumour.
Invades other tissues and spreads much faster than a benign tumour.
Describe the 2 types of growths which can arise from squamous epithelium.
- Benign called “papilloma”
2. Malignant called “squamous cell carcinoma”
Name the 2 growth types from glandular epithelium, eg salivary.
- Benign called “adenoma”
2. Malignant called “adenocarcinoma”
Name the 2 growth types from smooth muscle.
Benign - leiomyoma
Malignant - leiomyosarcoma
Name the 2 growth types from fibrous tissue
- Benign - fibroma
2. Malignant - fibrosarcoma
Name the 2 growth types from bone
- Benign - osteoma
2. Malignant - osteosarcoma
Name the 2 growth types from cartilage
- Benign - chondroma
2. Malignant - chondrosarcoma
Name the 2 growth types from fat
- Benign - Lipoma
2. Malignant - liposarcoma
Name the 2 growth types from a blood vessel
- Benign- angioma
2. Malignant - angiosarcoma
Name 2 chemical carcinogens.
drugs and alcohol
Name the 3 stages of tumour formation.
- Initiation (permanent DNA damage)
- Promotion (agent promotes proliferation)
- Latent period (time from promotion to tumour)
Give an example of physical carcinogenesis.
Ionising radiation
