L68. Growth Disturbances Flashcards
What are the 2 types of growth disturbances?
Developmental or acquired
Name the 3 hamartomas.
Agenesis
Aplasia
Hypoplasia
Describe agenesis
tissue/organ does not develop at all.
Describe aplasia
Organ/tissue is there but doesn’t develop the normal structure
Describe hypoplasia
Structure is there but the amount is less than normal eg. enamel
What can cause enamel hypoplasia?
Taking in too much fluoride
Describe the difference between a hamartoma and a benign tumour.
A hamartoma grows till the person stops growing but a benign tumour continues to grow.
What is a haemangioma?
non-cancerous growth of blood vessels
what is a vascular malformation?
A clump of blood vessels on the tongue.
Describe the cellular difference between a benign tissue and hamartoma.
Benign tissue has a fibrous connective tissue capsule, a hamartoma does not.
What is a lymphangioma?
Collection of lymph cells
Give an example of development in the wrong place.
Ectopic teeth
What is atrophy?
decrease in cell numbers
What is hypertrophy?
Increase in cell size
What is hyperplasia?
cell numbers increase
What is metaplasia?
cells change from one epithelium type to another, but not epithelium to connective tissue.
What is dysplasia?
a change in the cell’s growth pattern (higher instances of malignancies)
When does atrophy of the mandible occur?
When all the teeth are removed at a young age.
Describe how post-menopausal osteoporosis occurs.
Oestrogen inhibits osteoclasts from resorbing bone. When oestrogen levels fall, osteoclast activity increases.
Describe the difference in treatment for controlled and uncontrolled hyperplasia.
Controlled hyperplasia can be regressed by intervention.
Uncontrolled hyperplasia could be a tumour.
Give an example of physiological hypertrophy.
muscle cells increasing in size
Give the change (metaplasia) in smokers respiratory tracts.
ciliated columnar -> squamous
Give the change (metaplasia) in barrett’s oesophagus
squamous -> columnar
What is neoplasia?
malignant or benign abnormal mass of tissue