L40. Endocrine 2 Flashcards

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1
Q
Name the following in moles :
1x10-3
1x10-6
1x10-9
1x10-12
1x10-15
1x10-18
A
millimole
micromole
nanomole
picomole
femtomole
attomole
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2
Q

Do we want to store large volumes of active hormone in the body?

A

No in case they are released in a trauma accident

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3
Q

Name a vasoconstrictor

A

Adrenaline

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4
Q

What kind of condition means adrenaline wouldn’t be removed from the blood quickly?

A

kidney condition

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5
Q

What does circadian refer to?

A

Daily rhythm

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6
Q

Name two roles of the hypothalamus

A

thermoregulation

circadian rhythm

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7
Q

what kind of feedback is used in thermoregulation?

A

Negative feedback

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8
Q
  • Describe how hormones reach the anterior pituitary from the hypothalamus.
A

The hypothalamus releases hormones which pass to the anterior pituitary via blood vessels (portal vessels)

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9
Q
  • how do hormones reach the posterior pituitary gland?
A

Hypothalamus-produced hormones pass to the posterior pituitary along nerve axons where they are released into circulation.

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10
Q

Name a hypothalamic hormone.

A

growth hormone-releasing hormone

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11
Q

Name an anterior pituitary hormone.

A

Growth hormone

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12
Q

Give an example of a posterior pituitary hormone

A

ADH

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13
Q

Give 2 examples of pathways from stimulus to target organ involving the hypothalamus.

A

Stimulus > hypothalamus > anterior pituitary > target organ

Stimulus > hypothalamus > posterior pituitary > target organ

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14
Q

What kind of cells create calcitonin?

A

Para-follicular “c-cells”

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15
Q

What are the names of the following?
T3
T4

A

Tri-iodo-thyronine

Tetra-iodo-thyronine

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16
Q

Which is more potent? T3 or T4?

A

T4 is a more potent precursor of T3

17
Q

What do T3 and T4 do?

A

Increase cell metabolic rate and determine basal metabolic rate

18
Q

Name 2 thyroid disorders

A

hypothyroidism

hyperthyroidism

19
Q

Which of the following can be treated? Congenital or adult hypothyroidism?

A

Adult can be treated

20
Q

Discuss the causes of a goitre

A

Thyroid swelling associated with an iodine deficiency (found in salt). Low thyroxine levels cause excess TSH secretion.