L29. Ventilation and Perfusion Flashcards

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1
Q

Describe what is meant by ventilation.

A

Air moving in and out of the lungs

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2
Q

Describe what is meant by perfusion

A

deoxygenated blood moving into the lungs and becoming oxygenated

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3
Q

What is the V/Q ratio?

A

When P O2 and P CO2 levels are maintained by ventilation and perfusion

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4
Q

Are alveoli in the apex or base more expanded? Why

A

Apex due to gravity

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5
Q

What is compliance? What does high compliance mean? Give an example of where you would see reduced compliance.

A

How much effort is required to stretch the lung wall.
High compliance = easily
Decreased compliance = pulmonary condition

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6
Q

What is anatomical dead space?

A

the total volume of the conducting airways

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7
Q

What is physiological dead space?

A

The total volume what doesn’t participate in gas exchange

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8
Q

Name the 2 types of blood circulation.

A
  1. pulmonary circulation - brings deoxygenated blood from heart to lungs, and oxygenated blood from lungs to heart.
  2. Bronchial circulation - brings oxygenated blood to the alveoli
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9
Q

Describe the pressures of systemic and pulmonary circulation.

A

Systemic : high pressure, high resistance

Pulmonary : low pressure, low resistance

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10
Q

What is arterial hypoxemia?

A

When arterial P O2 is less than 80mmHg

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11
Q

Give the values for Hypoxia.

A

P O2 is less than 60mmHg

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12
Q

Give the values for hypercapnia

A

P CO2 is greater than 40mmHg

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13
Q

Give the values for hypocapnia

A

P CO2 is less than 35mmHg

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14
Q

Describe an anatomical shunt.

A

When mixed venous blood is “shunted” into arterial blood.

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15
Q

What is a right to left shunt? Where do shunts often take place?

A

blood being shunted (added) is deoxygenated.

In the heart - right atrium/ventricle blood crosses the septum into the left atrium/ventricle.

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16
Q

What is a physiological shunt?

A

When blood in non-ventilated alveoli (deoxygenated) is mixed with oxygenated blood.

17
Q

What is atelectasis?

A

obstruction of ventilation due to mucous plugs

18
Q

What is happening when V/Q = 0?

A

no ventilation to one area = choking

19
Q

What is happening when V/Q is low?

A

asthma

20
Q

What is happening when V/Q = infinity?

A

no blood flow eg pulmonary embolism

21
Q

What is happening when V/Q is high?

A

decreased gas exchange eg pulmonary fibrosis

22
Q

What is COPD and what does it mean?

A

Chronic obstructive pulmonary disease

airflow is obstructed (long term smoking)

23
Q

What are the causes of Emphysema?

A

Low elastic recoil - inhalation is easy, exhalation is hard

24
Q

What is chronic bronchitis?

A

Inflammation of bronchi

25
Q

What is pulmonary fibrosis?

A

Irregular air spaces in the alveoli

26
Q

What is the V/Q value for a healthy lung?

A

0.8

27
Q

What does V/Q of >1 mean?

A

Ventilation exceeds perfusion

28
Q

What does V/Q < 1 mean?

A

perfusion exceeds ventilation

29
Q

What is pulmonary circulation?

A

Blood from heart to lungs and lungs to heart

30
Q

What is systemic circulation?

A

Blood from the heart to the rest of the body