Krebs, etc, oxidative phosphorylation Flashcards
pyruvate reaction turning it into acetyl coa
oxidative carboxylation
oxaloacetate combines with what to get citrate
acetyl coa
citrate turns into
cis-acotinic
cis-aconitic turns into
isocitrate
isocitrate converts
nad+ into nadh
isocitrate turns into
ketoglutarate
ketoglutarate converts
nad+ into nadh
a-ketoglutarate turns into
succinyl coa
succinyl coa turns into
succinate
succinate turns into
fumarate
fumarate converts
fad into fadh
h2o enters where
between fumarate and malate
fumarate turns into
malate
malate converts
nad+ into nadh
malate turns into
oxaloacetate
what is the rate limiting step in krebs
dehydrogenase
what does atp inhibit
pyruvate dehydrogenase complex
citrate synthase
isocitrate dehydrogenase
what does nadh inhibit
pyruvate dehydrogenase complex
citrate synthase
alpha ketoglutarate
what does citrate inhibit
citrate synthase
what is needed to start krebs
pyruvate –> acetyl coa
enzyme that converts pyruvate into acetyl coa
pyruvate dehydrogenase complex
what is needed for pyruvate to convert into acetyl coa
thiamine pyrophosphate (b1) fad (b2) coa (b5) lipoic acid nad (b3)
products made from pre-krebs
acetyl coa, nadh, co2
krebs cycle aka
citric acid cycle, tricarboxylic acid cycle, tca cycle
where does krebs cycle happen
mitochondria
what condition does krebs require
aerobic conditions
how is gtp formed
by succinyl coa synthase (succinyl coa –> succinate)
what does succinate dehydrogenase require
fad (succinate –> fumarate)
what is succinate thiokinase
production of atp in krebs
what is produced by 1 krebs cycle
2 CO2, 3NADH, 1FADH2, 1GTP/ATP
aka for electron transport chain
etc, cytochrome series, respiratory chain
etc multistep reaction
complex of enzyme in inner fold of inner mitochondrial membrane
what does the etc release
energy
hydrogen ions from nadh and fadh2
what is the electron acceptor in the etc
oxygen (forms h2o)
oxidative phosphorylation
atp production
where is energy released from in oxidative phosphorylation
etc
what generates atp in oxidative phosphorylation
energy released from etc used by atp synthetase
what are coupled together
etc and oxidative phosphorylation
how many atp from nadh
3
how many atp from fadh2
2
how many atp does krebs make
30
how many atp does glycerol-3-phosphate shunt make
4
how many atp does glycolysis make
2
what is the total atp made
36 or 38