Krebs, etc, oxidative phosphorylation Flashcards

1
Q

pyruvate reaction turning it into acetyl coa

A

oxidative carboxylation

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2
Q

oxaloacetate combines with what to get citrate

A

acetyl coa

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3
Q

citrate turns into

A

cis-acotinic

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4
Q

cis-aconitic turns into

A

isocitrate

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5
Q

isocitrate converts

A

nad+ into nadh

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6
Q

isocitrate turns into

A

ketoglutarate

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7
Q

ketoglutarate converts

A

nad+ into nadh

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8
Q

a-ketoglutarate turns into

A

succinyl coa

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9
Q

succinyl coa turns into

A

succinate

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10
Q

succinate turns into

A

fumarate

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11
Q

fumarate converts

A

fad into fadh

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12
Q

h2o enters where

A

between fumarate and malate

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13
Q

fumarate turns into

A

malate

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14
Q

malate converts

A

nad+ into nadh

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15
Q

malate turns into

A

oxaloacetate

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16
Q

what is the rate limiting step in krebs

A

dehydrogenase

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17
Q

what does atp inhibit

A

pyruvate dehydrogenase complex
citrate synthase
isocitrate dehydrogenase

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18
Q

what does nadh inhibit

A

pyruvate dehydrogenase complex
citrate synthase
alpha ketoglutarate

19
Q

what does citrate inhibit

A

citrate synthase

20
Q

what is needed to start krebs

A

pyruvate –> acetyl coa

21
Q

enzyme that converts pyruvate into acetyl coa

A

pyruvate dehydrogenase complex

22
Q

what is needed for pyruvate to convert into acetyl coa

A
thiamine pyrophosphate (b1)
fad (b2)
coa (b5)
lipoic acid
nad (b3)
23
Q

products made from pre-krebs

A

acetyl coa, nadh, co2

24
Q

krebs cycle aka

A

citric acid cycle, tricarboxylic acid cycle, tca cycle

25
where does krebs cycle happen
mitochondria
26
what condition does krebs require
aerobic conditions
27
how is gtp formed
by succinyl coa synthase (succinyl coa --> succinate)
28
what does succinate dehydrogenase require
fad (succinate --> fumarate)
29
what is succinate thiokinase
production of atp in krebs
30
what is produced by 1 krebs cycle
2 CO2, 3NADH, 1FADH2, 1GTP/ATP
31
aka for electron transport chain
etc, cytochrome series, respiratory chain
32
etc multistep reaction
complex of enzyme in inner fold of inner mitochondrial membrane
33
what does the etc release
energy | hydrogen ions from nadh and fadh2
34
what is the electron acceptor in the etc
oxygen (forms h2o)
35
oxidative phosphorylation
atp production
36
where is energy released from in oxidative phosphorylation
etc
37
what generates atp in oxidative phosphorylation
energy released from etc used by atp synthetase
38
what are coupled together
etc and oxidative phosphorylation
39
how many atp from nadh
3
40
how many atp from fadh2
2
41
how many atp does krebs make
30
42
how many atp does glycerol-3-phosphate shunt make
4
43
how many atp does glycolysis make
2
44
what is the total atp made
36 or 38