Cardiovascular physiology Flashcards

1
Q

what is average bpm

A

75

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2
Q

what is average mL blood per beat

A

70-80mL

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3
Q

where is the heart located

A

behind 2-5th ribs

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4
Q

normal bp

A

120/80

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5
Q

what is the pacemaker

A

sinus (SA) node

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6
Q

what is the sa node innervated by

A

cn10, decreases hr

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7
Q

sa node prevents

A

tetany

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8
Q

where in the heart has the highest frequency of spontaneous contractions

A

sa node

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9
Q

what takes over as the pacemaker if sa node dies

A

a-v node

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10
Q

what part of the heart is affected from mitral stenosis

A

left atrium

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11
Q

what part of the heart is affected from tricuspid stenosis

A

right atrium

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12
Q

what part of the heart is affected from aortic stenosis

A

left ventricle

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13
Q

what part of the heart is affected from pulmonic stenosis

A

right ventricle

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14
Q

ratio of na:k that maintains resting state of heart

A

3 na+ for every 2k

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15
Q

what structure in the heart produces rapid conduction of ap

A

purkinje fibers

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16
Q

what occurs at P in ECG

A

atrial depolarization

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17
Q

length between S-T in ECG

A

.04 to .06 seconds

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18
Q

what occurs at QRS in ECG

A

ventricular depolarization and atrial repolarization

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19
Q

what occurs at T in ECG

A

ventricular repolarization

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20
Q

EKG and ECG are diagnostic for

A

heart

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21
Q

EMG is diagnostic for

A

muscle

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22
Q

EEG is diagnostic for

A

brain

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23
Q

when there is aortic regurgitation there is

A

mitral stenosis

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24
Q

when there is pulmonic regurgitation there is

A

tricuspid stenosis

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25
frank starlings law aka
maestrini hearts law
26
frank starlings law
stroke volume increase in repsonse to increase volume of blood filling the heart (inc SV = inc venous return)
27
davis law
muscle will increase in size when used
28
boyles law
inversely proportional relationship between absolute pressure and volume of gas, if tem. kept constant within a closed system
29
pV=k
p: pressure of system V: denotes volume of gas k: constant pressure and volume of system
30
poiseuilles law
radius ^4
31
what are precursor platelets
megakaryocytes
32
where are RBC's (erythrocytes) producced
marrow in children and adults
33
function of erythrocytes
carry hemoglobin
34
where does the production of erythrocytes in fetus occur
liver, spleen, lymph, bone marrow
35
where does the production of erythrocytes in adults occur
membranous bone marrow
36
genesis of erythrocytes
hemocytoblast --> normoblast --> reticulocyte --> erythrocyte (99% of blood - no nucleus)
37
what is made in the kidney stimulating RBC production
erythropoietin
38
life of RBC
120 days
39
where do RBC go when recycled
spleen to preserve heme
40
how is CO2 transported in blood
by plasma bicarbonate
41
what is iron transported as
transferrin
42
what is iron stored as
ferritin
43
what is iron absorbed as
fe2
44
what is required to absorb iron
vitamin c to remain reduced
45
what has the greatest o2 binding affinity
iron protoporphyrin IX
46
blood clot process
injury --> constriction --> platlet plug --> clot --> repai
47
what activates prothrombin activator
extrinsic (damaged cells) and intrinsic (foreign bodies)
48
what does prothrombin activator do
prothrombin --> thrombin
49
what does thrombin become
fibrinogen
50
what does fibrinogen bevome
fibrin
51
what mixes with RBC, platelets and plasma to clot blood
fibrin
52
clotting factor I
fibrinogen
53
clotting factor II
prothrombin
54
clotting factor III
thromboplastin
55
clotting factor IV
calcium
56
clotting factor V
proaccelerin
57
clotting factor VII (no VI)
proconvertin
58
clotting factor VIII
antihemophilic - von willebrand carrier
59
clotting factor IX
antihemophilic factor B
60
clotting factor X
stuart factor
61
clotting factor XI
antih. C
62
clotting factor XII
hangeman factor (most important)
63
what are the macrophages in the aveoli
alveolar macrophages | dust cells
64
what are the macrophages in the brain
microglial cells
65
what are the macrophages in the liver
kupffer cells
66
what are the macrophages in tissue
histiocyte or fixed macrophages