Amino acids + proteins Flashcards

1
Q

amino acids are all in L-form except

A

glycine

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2
Q

amphoteric

A

acid or basic

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3
Q

essential amino acids

A
phenylalanine
valine
tryptophan
threonine
isoleucine
methionine
histidine (arginine)
leucine (maple syrup disease)
lysine
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4
Q

semi-essential

A

histadine

arginine

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5
Q

aromatic ring

A

aka benzine ring
phenylalanine
tryptophan
TYROSINE

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6
Q

basic (positive charge at nuetral ph)

A

histidine
arginine
lysine

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7
Q

neutral

A

serine
threonine
asparagine
glutamine

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8
Q

sulfur containing

A

methionine

cysteine

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9
Q

not glucogenic

A

leucerine

lysine

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10
Q

branch chain

A

leucine
isoleucine
valine

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11
Q

acidic

A

glutamate

aspartate

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12
Q

aliphatic chain

from less hydrophilic to more hydrophilic

A
glycine
alanine
valine
leucine
isoleucine
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13
Q

serotonin is precursor to

A

tryptophan

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14
Q

GABA is precursor to

A

glutamate

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15
Q

histamine is precursor to

A

histidine

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16
Q

creatine is precursor to

A

glycine and arginine

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17
Q

NAD is precursor to

A

tryptophan

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18
Q

what are amino acid food sources

A

meats, fish, eggs, dairy, peanut butter, grains

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19
Q

digestion of amino acids

  1. mouth
  2. stomach
  3. small intestine
A
  1. none, ptyalin
  2. pepsin, HCLM renin(infcancy and childhood only)
  3. trypsin, chymotrypsin, carboxypeptidase, amino peptidase, dipeptidase
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20
Q

what are the isoflavones in soy

A

genistein, daidzein, glycitein

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21
Q

what do legumes lack

A

methionine

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22
Q

which amino acids lack in grains

A

lysine, threonine and tryptophan

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23
Q

pathway of phenylalanine to epi

A

phenylalanine –> tyrosine –> l-dopa (also turns into melanin) –> dopamine –> nor epi –> epi

24
Q

aa metabolims route

A

trasamination then oxidative deamination

25
where does removed ammonia go
carried to urea cycle by glutamate
26
what are the left over carbon skeletons of aa
1. glucogenic (form pyruvate or oxaloacetate to make glucose) 2. ketogenic (form acetyl coa or acetoacetyl coa to make ketones)
27
what makes glucose
pyruvate or oxoloacetate
28
what makes ketones
acetyl coa or acetoacetyl coa
29
what is the conversion of alanine
pyruvate (vice versa)
30
what is the conversion of glutamine
glutamate (vice versa) a ketoglutarate
31
what is the conversion of aspargine
aspartate
32
what is the conversion of serine
pyruvate(vice versa)
33
what are oxidized to make uric acid
purines
34
what are the 3 aa that donate nitrogen for purines and pyrimidines
glutamate, aspartate, asparagine
35
what are the 6 aa that muscle is able to oxidize
glutamate, aspartate, leucine, valine, isoleucine, asparagine
36
aka for glucose alanine cycle
lactic acid cycle | cori cycle
37
what does the muscle make during exercise
ammonia from amino acids | lactate from glucose
38
what makes alanine
ammonia and lactte
39
what does the liver do in the glucose alanine cycle
converts alanine back into lactate and ammonia
40
what happens to ammonia and lactate in the glucose alanine cycle
ammonia --> urea | lactate --> glucose
41
what process is it called when lactate becomes glucose
gluconeogenisis
42
what is the last process of the glucose alanine cycle
glucose returns to the muscle via blood
43
what is the function of the urea cycle
rids body of toxic ammonia
44
what is the enzyme in the urea cycle
carbamoyl phosphate synthetase
45
what does carbamoyl phosphate synthetase produce
carbamoyl phosphate
46
what is the rate limiting enzyme in the urea cycle
carbamoyl phosphate synthase
47
what does carbamoyl phosphate synthetase require
ATP and Mg
48
what are the important intermediates in the urea cycle
fumarate, arginine, citrulline, ornithine, glutamate, aspartate
49
what are the bonds between aa
peptide bond
50
what does glucagon turn into
peptide hormone
51
primary structure of proteins
number and sequence of amino acids; determines proteins structure
52
secondary structure of proteins
alpha helix and beta pleated sheet
53
aka for beta pleated sheet
beta bend
54
tertiary structure of proteins
max fold for function
55
quaternary structure of proteins
more than one chain | best ex. hemoglobin which has four chains