Kidney Flashcards
What are 6 possible oral manifestations of Kidney disease?
1-Halitosis (due to uremia) 2-Uremic stomatitis 3-Bleeding 4-Bone abnormalities 5-Gingival overgrowth 6-Infectious complications
What are 5 features of a glomerulus?
1-Mesangium (support) 2-Capillary loop 3-Epithelial side 4-Endothelial side 5-bowmans space
What is characterized by heavy proteinuria (>3.5 g/day), edema and hypoalbuminemia?
Nephrotic Syndrome
What is characterized by active urine sediment, hypertension and kidney dysfunction?
Nephritic Syndrome
What is characterized by inflammatory injury to the kidney and may be related to immune deposits in the glomeruli or other inflammatory injuries?
Glomerulonephritis
What is characterized by chronic glomerular injury/scarring?
Glomerular sclerosis
Scarring of the entire glomerular tuft is called?
Global glomerular sclerosis
Scarring of a portion of the glomerular tuft is called?
Segmental glomerular sclerosis
What is the leading cause of kidney failure?
Diabetes
*44% of new cases
What condition is a result of microvascular injury in arterioles and glomerular capillaries due to advanced glycosylation products?
Diabetic Nephropathy
*Mesangial expansion/sclerosis, arteriolar hyalinosis
What is the second leading cause of kidney disease?
Hypertension
*African americans up to 6 times more likely to have complications from hypertension
What is the most common primary glomerulonephritis world-wide and presents with proteinuria, hematuria and kidney dysfunction?
IgA Nephropathy
*more common in asians
What is the most common cause of nephrotic syndrome in white adults, is often treated with immunosuppressive therapy and of which 1/3 of patients will progress to end stage kidney disease?
Membranous Glomerulopathy
*Antigens and boune antibodies aggregate between the basement membrane and podocyte
