INTRO TO PHARMACOLOGY Flashcards
what is pharmacology?
actions, mechanisms, uses and adverse effects of drugs
what is a drug?
any natural or synthetic substance which alters the state of a living organisms
what classes of drugs are there?
medicinal or non-medicinal
define pharmacodynamics
what the drug does to the body (how it acts, what side effects it may produce)
define pharmacokinetics
what the body does to the drug (how it gets into and out of the body)
how are drugs discovered?
natural sources: plants, animals, minerals
understanding neurotransmitters and hormones
improving naturally occurring drugs
where do ideas for new drugs come from?
understanding mediators of disease
understanding enzymes, substrates, products
how are drugs names?
generic, brand or proprietary
how are drugs classified?
molecular action
chemical structure
pharmacotherapeutic action
BNF
how so drugs work on a cellular level?
On transport systems of membranes
On enzymes
On receptors
what are type 1 receptors?
ionotropic: receptor linked to ion channel
what are type 2 receptors?
metabotropic: G-protein-linked receptors
what are type 3 receptors?
tyrosine kinase linked receptors
what are type 4 receptors?
DNA-linked receptors/intracellular receptors
what does compliance mean?
is the patient taking the drug as directed?