ANTIBIOTICS + ANTIBIOTIC RESISTANCE Flashcards

1
Q

what does a bacteria cell contain?

A
Cell Wall
Cell membrane
No nuclear membrane
(DNA)
Ribosome (30s)(50s)
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2
Q

what does a mammalian cell contain?

A
No Cell Wall
Cell membrane 
Nuclear membrane
(DNA)
Ribosome (40s)(60s)
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3
Q

what are the distinguishing features of bacteria?

A
shape
growth requirement 
cell wall
DNA 
ribosomes
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4
Q

what are growth requirements?

A

Optimum temperature
Optimum pH
Atmospheric conditions
nutrients

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5
Q

what is aerobic?

A

is any organism that does not require oxygen for growth

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6
Q

what is anaerobic?

A

which grows in the presence of air or requires oxygen

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7
Q

what is facultative?

A

can use oxygen but also has anaerobic methods of energy production

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8
Q

what are the 3 main groups of bacteria?

A

gram stained bacteria
acid-fast bacilli
atypicals

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9
Q

what are the different types of gram stained bacteria?

A

Gram positive
aerobes or anaerobes
Gram negative
aerobes or anaerobes

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10
Q

what is acid-fast bacilli?

A

mycobacteria

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11
Q

what are atypicals?

A

Chlamydiae, Rickettsiae & Mycoplasmas not classed as bacteria

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12
Q

what is the purpose of the gram stain procedure?

A

distinguishes betweenGram+ve andGram-ve groups by colouring these cells red or violet

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13
Q

what colour does Gram +ve produce and why?

A

(blue/purple)

Thick peptidoglycan cell wall retains primary stain

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14
Q

what colour does Gram -ve produce and why?

A

(pink/red)

Thin peptidoglycan cell wall does not retain primary stain and is protected by a lipophilic outer cell memb

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15
Q

What are the portals of entry into the body for micro-organisms?

A
Skin
Respiratory tract
GI tract
Urinogenital system
Conjuctiva
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16
Q

what are antibiotics?

A

a medicine that inhibits the growth of or destroys microorganisms

17
Q

define antibacterial

A

destructive to or inhibiting the growth of bacteria

18
Q

define antimicrobial

A

destroying or inhibiting the growth of microorganisms and especially pathogenic microorganism

19
Q

define disinfectant

A

a chemical liquid that destroys bacteria

20
Q

define bactericidal

A

adrugorsubstancewhichkillsbacteria,oriscapableofkillingbacteria

21
Q

define bacteriostatic

A

Capable of inhibiting the growth or reproduction of bacteria

22
Q

what are beta lactams?

A

interfere with cross linkage of peptidoglycans

bactericidal

23
Q

give examples of beta lactams

A

penicillins, cephalosporins

24
Q

what are glycopeptides?

A

inhibit peptidoglycan formation

bactericidal