Integument Flashcards
How big is the integumentary organ system?
1.2-2.2 meters squared in area
What is the largest organ system?
The integumentary system
What percent of body weight is made up by the integumentary system?
7%
What are the two parts of the integument?
The cutaneous membrane (skin) and accessory structures (hair, nails, etc)
What are the parts of the cutaneous membrane?
The outer membrane (superficial epithelium) and the inner dermis
What is the outer membrane?
The superficial epithelium/ epithelial tissues of the cutaneous membrane
What is the inner dermis?
The connective tissues of the cutaneous membrane
Where do accessory structures originate?
They originate in the dermis
What are accessory structures?
A part of the integument that originates in the dermis and extends through the epidermis to the skin surface
What are some examples of accessory structures?
Hair, skin, nails, and multicellular exocrine glands
What are the functions of the skin?
Protect, excrete, maintain temperature, synthesize, store, adn detect
What does the skin protect?
The underlying tissues and organs
What does the skin excrete?
The skin excretes salt, water, and organic wastes (through glands)
How does the skin maintain body temperature?
Through insulation and evaporation
What does the skin synthesize?
Vitamin D3
What does the skin store?
Lipids
What does the skin detect?
Touch, pressure, pain, and temperature
What types of cells make up the epidermis?
Avascular stratified squamous epithelial cells
How do cells in the epidermis get nutrients and oxygen?
Nutrients and oxygen diffuse form the capillaries in the dermis
What types of cells make up the epidermis?
Avascular stratified squamous epithelial cells
How do cells in the epidermis get nutrients and oxygen?
Nutrients and oxygen diffuse form the capillaries in the dermis
What are the types of cells in the epidermis?
Keratinocytes, melanocytes, langerhans cells, and corneocytes
What are keratinocytes?
Found in the epidermis, keratinocytes contain large amounts of keratin, and they’re the most abundant cells in the epidermis
What are the most abundant cells in the epidermis?
Keratinocytes
What are melanocytes?
Found in the epidermis, melanocytes produce a yellow-brown or black pigment
What are langerhans cells?
Found in the epidermis, langerhans cells support the immune system
What are corneocytes?
Found in the epidermis, corneocytes are non-living keratinized cells, and comprise the top layer of the epidermis.
What makes up the top layer of the epidermis?
Corneocytes
What is the mnemonic for the layers of the epidermis?
Come, Let’s Get SunBurnt
What are the 5 layers of the epidermis?
[Stratum] Corneum, lucidum granulosum, spinosum, basale
What is the stratum basale?
The germative layer of the epidermis
What is unique about the stratum basale in the epidermis?
It has many stem cells and is the only layer to have mitosis
How is the stratum basale attached, and to what?
The stratum basale is attached to basal lamina by hemidesmosomes
What are hemidesmosomes?
The anchors that keep the stratum basale attached to the basal lamina; keeps the stratum basale from falling off. Creates a strong bond between the epidermis and dermis
Where are melanocytes found?
In the stratum basale
What percent of the stratum basale layer is made up by melanocytes?
10-25% of the cells in the stratum basale layer are melanocytes
What layer are epidermal ridges found in?
The stratum basale
What are epidermal ridges?
Like fingerprints
What are dermal papillae?
Tiny mounds found in the stratum basale layer of the epidermis
What do dermal papillae do?
They increase the surface area of the basal lamina, and strengthen the attachment between the epidermis and dermis.
How is the stratum spinosum produced?
It’s produced by the division of the stratum basale
What makes up the stratum spinosum?
8-10 layers of keratinocytes bound to each other by desmosomes
What is unique about the stratum spinosum?
It has langerhans cells
What are langerhans cells?
Cells that defend against pathogens as an immune response
What is a possible use for langerhans cells?
Attacking skin cancers
Where are langerhans cells made?
They’re made in the bone marrow/ spongy bone
What makes up the stratum granulosum?
3-5 layers of keratinocytes
Does the stratum spinosum produce keratin?
The spinosum layer has keratinocytes but doesn’t produce a lot of keratin
What layer starts producing a significant amount of keratin?
The stratum granulosum starts producing keratin
What is keratin?
It’s a tough, fibrous protein that makes up the hair and nails