Idek man Flashcards
what type of cells make up our mucous membranes?
columnar epithelium cells
how can the mucosal membrane barrier be compromised? (3 broad groups and one example of each)
- Respiratory Tract (smoking, respiratory infections, cold temp and low moisture)
- Digestive tract (ulcers/wounds/breaks, constipation, acid reflux)
- Reproductive tract (intercourse, ulcers, lesions via STDs)
what two sentinel cells should we know for class? what’s a broader name for sentinel cells and what immune system are they a part of?
macrophages, dendritic cells. phagocytes, innate immune system.
what three ways do sensory cells communicate?
cytokines (voice)
surface receptors (eyes, ears)
adhesion molecules (hands)
what is the language used by the immune system?
cytokines
what are cytokines?
small, soluble proteins which bind to receptors on other cells and signal the transcription and translation events within that cell
why would we want to know what cytokines do, i.e. what changes they make?
to use them therapeutically
what cytokines are used in cell communication (for this class’ purposes)?
chemokines
interferons
interleukins (ILs)
Tumor Necrosis Factor
TNF = ? what kind of cell is it?
tumor necrosis factor, cytokine
ILs = ? what kind of cells are they?
interleukins
name the anti inflammatory cytokines. name them now!
IL-10
name the pro inflammatory cytokines. name them now!
IL1, IL6, TNF
pro inflammatory or anti inflammatory: IL 10
anti
pro inflammatory or anti inflammatory: IL 1
pro
pro inflammatory or anti inflammatory: IL 6
pro