HSV and influenza Flashcards

1
Q

herpes simplex virus

A
vesicular lesions
lies dormant in nerves
mouth, face, eyes, CNS --> HSV 1
genitalila --> HSV 2
can be spread to baby via eyes

no cure

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2
Q

HSV meds

A

HSV 1 and 2/herpes zoster:
acyclovir
valacyclovir - prodrug w/increased absorption

must drink H2O; taken at onset of sx

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3
Q

issues w/HSV antivirals

A

HA, N/V, phlebitis (common)

crystal urea, altered mental status (rare)

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4
Q

HSV meds mechnism of action

A

activated by viral enzyme

spares healthy human cells

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5
Q

influenza vaccines

A

protection begins in 1-2wks
protection lasts 6mo (4 for elderly)
do NOT cause the flu

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6
Q

flu med

A

oseltamivir

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7
Q

mechanism of influenza

A

viral particles infect cell and an enzyme allows for release of viral particles into another cell

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8
Q

oseltamivir mechanism of action

A

block neuraminidase enzyme from releasing viral particles into new cells

most effective EARLY on when viral particles not released

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9
Q

issues w/oseltamivir

A

well-tolerated
N/V
take w/in 48h to decrease duration of sx
effective prophylactically, but not a substitute for vaccine

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