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NUR 409 Pharmacotherapeutics > Drugs and Classes > Flashcards

Drugs and Classes Flashcards

1
Q

captopril

A

RAAS - ACE inhibitor
hyperkalemia, orthostatic hypoTN, angioedema, persistent cough, neutropenia
cardioprotection

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2
Q

norepinephrine

A

adrenergic agonist
necrosis, tachycardia, HTN
monitor urine output, extremity perfusion
short half life

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3
Q

lovastatin

A

dislipidemia halt formation of VLDL, LDL
hepatotoxic, myopathic
rhabdomyolysis
avoid: grapefruit juice

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4
Q

atenolol

A 
β1 blocker slows HR, lowers BP
bradycardia, hypoTN, masked hypoglycemia d/t blocked adrenaline
HOLD if HR<50
do not abruptly discontinue
cardioprotection
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5
Q

losartan

A

RAAS - angiotensin II antagonist (ARB)

hyperkalemia, orthostatic hypoTN, angioedema

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6
Q

propranolol

A

β1, β2 blocker slows HR, lowers BP, bronchoconstricts
bradycardia, hypoTN, masked hypoglycemia d/t blocked adrenaline, bronchoconstriction!
HOLD if HR<50; contraindicated for pts w/resp dz
do not abruptly discontinue
cardioprotection

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7
Q

epinephrine

A

adrenergic agonist, combined w/local anesthetic
increases HR, BP, contractile force, bronchodilates, vasoconstricts
effects last 10-20mins
monitor urine output, extremity perfusion

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8
Q

nitroglycerin

A

anti-angina - widespread vasodilation at onset
headache (common), orthostatic hypoTN, reflex tachycardia, tolerance–>rest period needed
3 pill max, 5min b/w each
avoid: erectile dysfunction meds

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9
Q

digoxin

A

afib, heart failure - lower HR, increased contractile force
bradycardia, disrhythmias
toxicity: (early) N/V/anorexia, (late) yellow/halo vision, bradydysrhythmias, altered mental status, syncope
avoid: diuretics, ACE inhibitors, ARBs, antacids
must maintain nml K levels
hold if apical HR<60

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10
Q

lisinopril

A

RAAS - ACE inhibitor
hyperkalemia, orthostatic hypoTN, angioedema, persistent cough
cardioprotection

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11
Q

labetalol

A

β1, β2, and α1 blocker slows HR, lowers BP, bronchoconstricts, vasodilates

bradycardia, hypoTN, masked hypoglycemia d/t blocked adrenaline, bronchoconstriction
HOLD if HR<50; contraindicated for pts w/resp dz
do not abruptly discontinue
cardioprotection

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12
Q

mannitol

A

emergency diuretic reduces intracranial pressure/cerebral edema
may cause: heart failure, rebound intracranial pressure, metabolic acidosis, crackles
must be kept warm, used with filter d/t crystallization

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13
Q

carvedilol

A

β1, β2, and α1 blocker slows HR, lowers BP, bronchoconstricts, vasodilates

bradycardia, hypoTN, masked hypoglycemia d/t blocked adrenaline, bronchoconstriction
HOLD if HR<50; contraindicated for pts w/resp dz
do not abruptly discontinue
cardioprotection

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14
Q

enalapril

A

RAAS - ACE inhibitor
hyperkalemia, orthostatic hypoTN, angioedema, persistent cough
cardioprotection

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15
Q

dobutamine

A

adrenergic agonist
necrosis, tachycardia, HTN
increased cardiac workload
monitor urine output, extremity perfusion

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16
Q

furosemide

A

diuretic for edema or heart failure (too strong for HTN)
hypokalemia: fatigue, cramps, palpitations, N/V
tinnitus!!, hyperglycemia

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17
Q

atorvastatin

A

dislipidemia halt formation of VLDL, LDL
hepatotoxic, myopathic
rhabdomyolysis
avoid: grapefruit juice

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18
Q

diltiazem

A

calcium channel blocker - decrease BP, HR
HTN, angina pectoris, CCBS: peripheral edema, bradycardia, syncope
avoid: grapefruit juice

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19
Q

nifedipine

A

calcium channel blocker - decrease BP
HTN, angina pectoris, peripheral edema, syncope
avoid: grapefruit juice

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20
Q

niacin/nicotinic acid

A 
vitamin B3 (meat) - increases HDL, decreases LDL
intense flushing of the face, GI issues
may take aspirin 30min prior to admin
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21
Q

nitroprusside

A

HTN crisis - drastic drop in BP
must be protected from light
may cause cyanide poisoning

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22
Q

hydrochlorothiazide

A

diuretic, 1st drug of choice for HTN
hypokalemia: fatigue, cramps, palpitations, N/V
hyperglycemia

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23
Q

clonidine

A

anti-HTN
drowsiness, dry mouth
avoid: other CNS depressants

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24
Q

metaprolol

A 
β1 blocker slows HR, lowers BP
bradycardia, hypoTN, masked hypoglycemia d/t blocked adrenaline
HOLD if HR<50
do not abruptly discontinue
cardioprotection
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25
Q

dopamine

A

adrenergic agonist
necrosis, tachycardia, HTN
monitor urine output, extremity perfusion

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26
Q

simvastatin

A

dislipidemia halt formation of VLDL, LDL
hepatotoxic, myopathic
rhabdomyolysis
avoid: grapefruit juice

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27
Q

rosuvastatin

A

dislipidemia halt formation of VLDL, LDL
hepatotoxic, myopathic
rhabdomyolysis
avoid: grapefruit juice

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28
Q

amiodarone

A

cardiac dysrhythmias
baseline testing needed
dysrhythmias, hepatotoxicity, pulmonary toxicity, thyroid dysfunction, photosensitivity, visual disturbances

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29
Q

adenosine

A

IV push anti-dysrhythmic stops the heart
short half life
resuscitation equipment on hand
avoid: caffeine

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30
Q

isosorbide mononitrate

A

anti-angina - prophylactic widespread vasodilation
headache (common), orthostatic hypoTN, reflex tachycardia, tolerance–>rest period needed
avoid: crushing med, erectile dysfunction meds

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31
Q

spironolactone

A

diuretic
increases potassium levels–>hyperkalemia: arrhythmias, fatigue, cramps, palpitations, N/V
may cause endocrine issues
avoid: K rich foods, salt substitutes

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32
Q

verapamil

A

calcium channel blocker - decrease BP, HR
HTN, angina pectoris, CCBS: peripheral edema, constipation, bradycardia, syncope
avoid: grapefruit juice

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33
Q

amlodipine

A

calcium channel blocker - decrease BP
HTN, angina pectoris, peripheral edema, syncope
avoid: grapefruit juice

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34
Q

aspirin

A

antiplatelet aggregation
GI, renal impairment, tinnitus, diaphoresis, headache, acidic blood–>Kussmal resp
sx of bleeding: increased HR, decreased BP, ecchymosis, coffee-ground emesis, melena
avoid: herbals “g”

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35
Q

clopidogrel

A

antiplatelet aggregation
GI
sx of bleeding: increased HR, decreased BP, ecchymosis, coffee-ground emesis, melena
avoid: herbals “g”

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36
Q

heparin

A

rapid acting, short half-life anticoagulant
requires close monitoring of PTT:
nml = 40sec, therapeutic = 60-80sec
sx of bleeding: increased HR, decreased BP, ecchymosis, coffee-ground emesis, melena

antidote: protamine
avoid: herbals “g”

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37
Q

enoxaparin

A

rapid acting, longer half-life anticoagulant
less monitoring needed
must inject in subcutaneous “love handles”, don’t twist cap/aspirate, leave air bubble in syringe
must take at same time daily
sx of bleeding: increased HR, decreased BP, ecchymosis, coffee-ground emesis, melena
avoid: herbals “g”

antidote: protamine

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38
Q

warfarin

A

5 day delayed onset
must monitor PT/INR:
nml = 1, therapeutic = 2-3, mechanical heart valves = 3-4.5
must maintain vitamin K levels (leafy greens, mayo)
avoid: herbals “g”

antidote: vitamin K

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39
Q

protamine sulfate

A

antidote for heparin, enoxaparin anticoagulants

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40
Q

epoeitin alpha

A

anti-anemia - synthetic erythropoeitin

HTN, risk CV events, tumor progression

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41
Q

darbepoetin alpha

A

long acting anti-anemia - synthetic erythropoeitin

HTN, risk CV events, tumor progression

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42
Q

ferrous sulfate

A 
iron deficient anemia
take b/w meals w/OJ to increase absorption
nausea, constipation, dark green/melena
liquid form stains teeth
avoid: antacid, dairy, caffeine
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43
Q

iron dextran

A

iron deficient anemia

avoid: antacid, dairy, caffeine

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44
Q

cyanocobalamin

A

deficient anemia - vitamin B12

hypokalemia

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45
Q

blood

A

acute hemolytic rxn d/t ABO incompatability
sx occu w/in 20mins:
chills, fever, tachycardia, lower back pain, hematuria
stop transfusion STAT

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46
Q

metformin

A 
biguanide type II diabetes
anorexia, N/V/D, flatulence, vitamin B12/folic acid deficiency
lactic acidosis - rare
need CBC q3months, monitor kidneys
avoid: excess ETOH d/t lactic acidosis
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47
Q

glipizide

A

sulfonylurea type II diabetic
hypoglycemia, weight gain
take w/breakfast
avoid: ETOH d/t disulfiram-like rxn

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48
Q

glyburide

A

sulfonylurea type II diabetic
hypoglycemia, weight gain
take w/breakfast
avoid: ETOH d/t disulfiram-like rxn

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49
Q

glimepiride

A

sulfonylurea type II diabetic
hypoglycemia, weight gain
take w/breakfast
avoid: ETOH d/t disulfiram-like rxn

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50
Q

insulin

A

diabetes
hypoglycemia
increased affect w/sulfonylreas, beta blockers, ETOH
counteracted w/thiazide diuretics, glucocorticoids
may tx hyperkalemia

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51
Q

omeprazole

A 
proton pump inhibitor
slow onset, short half-life
rebound sx: reflux, heartburn, gas
pneumonia, osteoporosis, hypomagnesemia
don't crush/chew; take before breakfast
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52
Q

esomeprazole

A 
proton pump inhibitor
slow onset, short half-life
rebound sx: reflux, heartburn, gas
pneumonia, osteoporosis, hypomagnesemia
don't crush/chew; take before breakfast
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53
Q

pantoprazole

A 
proton pump inhibitor
slow onset, short half-life
rebound sx: reflux, heartburn, gas
pneumonia, osteoporosis, hypomagnesemia
don't crush/chew; take before breakfast
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54
Q

lansoprazole

A 
proton pump inhibitor
slow onset, short half-life
rebound sx: reflux, heartburn, gas
pneumonia, osteoporosis, hypomagnesemia
don't crush/chew; take before breakfast
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55
Q

ranitidine

A 
H2 blocker - stomach
diminished effect over time
rebound sx if abruptly stopped
confusion w/poor renal function
avoid: antacid w/in 1h
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56
Q

cimetidine

A 
H2 blocker - stomach
diminished effect over time
rebound sx if abruptly stopped
confusion w/poor renal function
avoid: antacid w/in 1h
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57
Q

famotidine

A 
H2 blocker - stomach
diminished effect over time
rebound sx if abruptly stopped
confusion w/poor renal function
avoid: antacid w/in 1h
58
Q

ondansetron

A 
antiemetic
blocks 5HT3 (no effect on anxiety etc)
"clean"
headache, D/constipation, dizziness, prolonged QT interval-->torsades-->vFib
best if administered prophylactically
59
Q

promethazine (antiemetic)

A

antiemetic
H1 block: sedation, dry mouth
D2 block: EPS
A1 block: orthostatic hypoTN

do NOT give to children<2yo
infiltration causes gangrene

60
Q

metoclopramide

A

antiemetic
blocks D2, 5HT3 and promotes gastric motility
EPS, drowsiness
do NOT take >3months

61
Q

docusate sodium

A

stool softener

useful for: prophylactic, painful elimination, prevention of straining

62
Q

polyethylene glycol

A

osmotic laxative
BM in 2-4 days
well-tolerated
mix in 4-8 ounces of any fluid

63
Q

bisacodyl

A

stimulant (irritant)
BM in 12h PO, 1h PO
very STRONG, very harsh

64
Q

lactulose

A

osmotic
helps intestines excrete ammonia
expensive, flatulence, cramping

65
Q

alteplase

A

anticoagulant - dissolves clots
used for MI, stroke, central line clot
huge risk of bleeding

66
Q

sucralfate

A

coats stomach up to 6h
take before meals and 1h b/w other meds
constipation

67
Q

polyethylene glycol 3350 w/electrolytes

A

osmotic (pulls water)
used for bowel surgery or colonoscopy
massive diarrhea
pts must drink 1 gallon, may mix w/clear flavoring

68
Q

filgrastim

A

stimulates bone marrow to produce neutrophils
reduced risk of infection
bone pain (common), leukocytosis

69
Q

potassium chloride

A 
potassium supplement
GI irritation - take w/food/H20
irritating to veins - must dilute
MUST infused by pump w/cardiac monitor
NTI: 3.5-5mEq/L
70
Q

sodium bicarbonate

A

tx for aspirin toxicity w/activated charcoal, tx for hyperkalemia - makes K+–>cell

71
Q

sodium polystyrene sulfonate

A

laxative tx for hyperkalemia

72
Q

oxybutynin

A

overactive bladder - blocks M3 receptors
anticholinergic
tachycardia
contraindicated in pts w/glaucoma and myasthenia gravis

73
Q

ethinyl estradiol/norethindrone

A

oral contraceptive - no ovulation, thin wall, thick mucus
1 wk rest period w/placebo
DVT, PE, MI, stroke
increased breast tumor progression
avoid: st. john’s wort, antiseizure, certain abx

74
Q

norethindrone

A

oral contraceptive
doesn’t stop ovulation
no rest period
slightly lessened risk of DVT, PE, MI, stroke
avoid: st. john’s wort, antiseizure, certain abx
increased breast tumor progression

75
Q

tamsulosin

A

selective BPH alpha 1 blocker

abnl ejaculation

76
Q

doxazosin

A

nonselective BPH alpha 1 blocker

hypoTN, dizziness, nasal congestion, sleepiness

77
Q

finasteride

A

BPH 5 alpha reductase inhibitor
teratogenic
decreased libido, abnl ejaculation
falsely decrease PSA levels

78
Q

dutasteride

A

BPH 5 alpha reductase inhibitor
teratogenic
decreased libido, abnl ejaculation
falsely decrease PSA levels

79
Q

sildenafil

A

PDE5 inhibitor for erectile dysfunction, pulmonary HTN
hypoTN, priapism, sudden hearing loss
avoid: nitrates w/in 24h, alpha blockers

80
Q

tadalafil

A

PDE5 inhibitor for erectile dysfunction, BPH
hypoTN, priapism, sudden hearing loss
lasts 36h
avoid: nitrates w/in 24h, alpha blockers

81
Q

vardenafil

A

PDE5 inhibitor for erectile dysfunction
hypoTN, priapism, sudden hearing loss
avoid: nitrates w/in 24h, alpha blockers

82
Q

oxytocin

A 
increases strength, frequency, and length of contractions (induce labor)
use pump and monitor closely
STOP if:
resting uterine pressure>15-20mmHg
contraction duration>1min
contraction freq <2-3min
pronounced alteration of FHR or rhythm
83
Q

methylergonovine

A

controls postpartum bleeding and causes POWERFUL contractions
high risk of HTN

84
Q

terbutaline

A

suppresses preterm labor by activating beta2 uterine receptors to relax uterus
tachycardia, hypoTN, pulm edema, hyperglycemia

85
Q

magnesium sulfate

A

used for preeclampsia (prevent seizures)
NTI
toxicity: RR<12, loss of DTR, hypoTN, decreased urinary output
antidote: calcium gluconate

86
Q

calcium gluconate

A

antidote for magnesium sulfate toxicity

87
Q

amoxicillin

A

beta lactam abx
allergic rxn: rash to anaphylaxis w/in 30min
cross-sensitivity to cephalosporins

88
Q

cephalexin

A

beta lactam abx
allergic rxn
C.diff superinfection: watery diarrhea
antidote: metronidazole or vancomycin

89
Q

imipenem

A

beta lactam abx

90
Q

metronidazole

A

abx antidote for cephalosporin C.diff superinfection

91
Q

vancomycin

A

abx antidote for cephalosporin C.diff superinfection

ototoxic

92
Q

tetracycline

A 
tetracycline protein synth inhibitor abx
esophageal ulcer - avoid taking hs
food interactions - milk, Ca2+, Mg, Fe, antacids
teeth discoloration <8yo
photosensitivity
93
Q

erythromycin

A

macrolide protein synth inhibitor abx

metallic taste, prolonged QT intervals

94
Q

azithromycin

A

macrolide protein synth inhibitor abx

metallic taste, prolonged QT intervals

95
Q

gentamycin

A

aminoglycoside protein synth inhibitor abx

nephrotoxic, ototoxic, inactivated by -cillins if mixed together

96
Q

neomycin

A

aminoglycoside protein synth inhibitor abx

nephrotoxic, ototoxic, inactivated by -cillins if mixed together

97
Q

amikacin

A

aminoglycoside protein synth inhibitor abx

nephrotoxic, ototoxic, inactivated by -cillins if mixed together

98
Q

tobramycin

A

aminoglycoside protein synth inhibitor abx

nephrotoxic, ototoxic, inactivated by -cillins if mixed together

99
Q

streptomycin

A

aminoglycoside protein synth inhibitor abx

nephrotoxic, ototoxic, inactivated by -cillins if mixed together

100
Q

cipofloxacin

A

fluoroquinolone abx - UTI, traveller’s diarrhea, anthrax
achilles tendon rupture - avoid <18yo
photsensitivity - elderly, corticosteroids, organ transplant
food interactions - dairy, aluminum/Mg antacids, iron

101
Q

levofloxacin

A

fluoroquinolone abx
achilles tendon rupture - avoid <18yo
photsensitivity - elderly, corticosteroids, organ transplant
food interactions - dairy, aluminum/Mg antacids, iron

102
Q

moxifloxacin

A

fluoroquinolone abx
achilles tendon rupture - avoid <18yo
photsensitivity - elderly, corticosteroids, organ transplant
food interactions - dairy, aluminum/Mg antacids, iron

103
Q

norfloxacin

A

fluoroquinolone abx
achilles tendon rupture - avoid <18yo
photsensitivity - elderly, corticosteroids, organ transplant
food interactions - dairy, aluminum/Mg antacids, iron

104
Q

ofloxacin

A

fluoroquinolone abx
achilles tendon rupture - avoid <18yo
photsensitivity - elderly, corticosteroids, organ transplant
food interactions - dairy, aluminum/Mg antacids, iron

105
Q

sulfamethoxazole/trimethoprim

A

UTI - blocks bacterial folic acid creation at two different points in the pathway
hypersensitivity, crystalluria (drink 8+glasses H20), kernicterus
contraindicated in pregnant women and infants<2months

106
Q

nitrofurantoin

A

UTI - destroys bacterial DNA
brown urine, GI - take w/food, (rare) peripheral neuropathy
contraindicated in pt’s w/renal impairment

107
Q

phenazopyridine

A

UTI - analgesic to bladder mucosa
orange-red urine
GI - take w/food

108
Q

isoniazid

A 
TB
requires mult abx for 2mo-6yrs
hepatotoxicity
numerous CYP interactions
peripheral neuropathy
antidote: vitamin B6
109
Q

pyrazinamide

A

TB
requires mult abx for 2mo-6yrs
hepatotoxicity
numerous CYP interactions

110
Q

ethambutol

A 
TB
requires mult abx for 2mo-6yrs
hepatotoxicity
numerous CYP interactions
red-green color blindness
111
Q

rifampin

A 
TB
requires mult abx for 2mo-6yrs
hepatotoxicity
numerous CYP interactions
red-orange secretions
112
Q

vitamin B6

A

antidote for isoniazid peripheral neuropathy

113
Q

amphotericin B

A 
antifungal
phlebitis
nephrotoxic
hypokalemia - pump ONLY
anemia
infusion rxn: fever, chills, rigors, HA
tx: acetaminophen w/benadryl, or dantrolene
avoid: NSAIDs, aminoglycosides, diuretics
114
Q

ketocanazole

A

antifungal, well-tolerated

hepatotoxic, numerous CYP interactions

115
Q

fluconazole

A

antifungal, well-tolerated

hepatotoxic, numerous CYP interactions

116
Q

micoconazole

A

antifungal, well-tolerated

hepatotoxic, numerous CYP interactions

117
Q

acyclovir

A

HSV/herpes zoster antifungal
HA, N/V, phlebitis (common)
crystal urea, altered mental status (rare)
pt must drink H2O

118
Q

valacyclovir

A 
HSV/herpes zoster antifungal
prodrug w/increased absorption
HA, N/V, phlebitis (common)
crystal urea, altered mental status (rare)
pt must drink H2O
119
Q

oseltamivir

A

flu, well-tolerated
N/V
take w/in 48h to decrease duration of sx

120
Q

methotrexate

A 
rheumatoid arthritis - folic acid inhibitor
N/D (common), GI ulcer
decreased bone barrow production
pneumonitis
hepatotoxic
renal failure
infection
severe rash
121
Q

hydroxychloroquine

A 
rheumatoid arthritis, malaria
better tolerated, less effective
usually combined w.methotrexate
take w/food
retinal damage
122
Q

infliximab

A

rheumatoid arthritis - TNF blocker
common:
injection site rxn, infections

rare:
severe allergic rxn, heart failure, hepatotoxic, cancer

123
Q

adalimumab

A

rheumatoid arthritis - TNF blocker
common:
injection site rxn, infections

rare:
severe allergic rxn, heart failure, hepatotoxic, cancer

124
Q

etanercept

A

rheumatoid arthritis - TNF blocker
common:
injection site rxn, infections

rare:
severe allergic rxn, heart failure, hepatotoxic, cancer

125
Q

allopurinol

A 
prevention and tx gout, full effect in 1-2mo
effective if uric acid <6mg/mL
acute gout attack
hypersensitivity, hepatotoxicity (rare)
avoid: amoxicillin (hypersensitivity)
126
Q

colchicine

A

prevention and tx gout
diarrhea (common)
myopathy, bone marrow supression

127
Q

alendronate

A

osteoporosis bisphosphonate
take AM upright on empty stomach w/H2O
GI sx: heartburn, ab pain, diarrhea
hypocalcemia, osteonecrosis of the jaw

128
Q

ibandronate

A

osteoporosis bisphosphonate
take AM upright on empty stomach w/H2O
GI sx: heartburn, ab pain, diarrhea
hypocalcemia, osteonecrosis of the jaw

129
Q

risedronate

A

osteoporosis bisphosphonate
take AM upright on empty stomach w/H2O
GI sx: heartburn, ab pain, diarrhea
hypocalcemia, osteonecrosis of the jawv

130
Q

raloxifene

A

osteoporosis - mimics bone estrogen
hot flashes, leg cramp, edema, weight gain, thromboembolism, stroke
decreased cancer risk

131
Q

cycophosphamide

A 
CA - cytotoxic agent
tx wide variety of CA
bone marrow suppression, N/V, alopecia
damage to bladder mucosa-->hemorrhagic cystitis
antidote: 3L fluid daily, mesna
132
Q

cisplatin

A

CA - cytotoxic agent
derived from platinum
bone marrow suppression, N/V, alopecia
nephrotoxic, ototoxic

133
Q

methotrexate (CA)

A 
CA - cytotoxic agent
MASSIVE dose
bone marrow suppression, N/V, alopecia
nephrotoxic
antidote for healthy cells: leucovorin
134
Q

doxorubicin

A 
CA - cytotoxic agent
bone marrow suppression, N/V, alopecia
bright red-->turns urine and sweat red
cardiotoxic-->dysrhythmias
max dose: 550mg/m2
135
Q

vincristine

A

CA - cytotoxic agent

nerve damage–>neuropathy, decreased DTR, constipation, urinary hesitancy

136
Q

tamoxifen

A

hormonal agent - blocks estrogen receptors for breast CA
hot flashes, endometrial CA, blood clots
increases bone density, improves cholesterol
may be prophylactic

137
Q

leuprolide

A

hormonal agent - decreased production of testosterone for prostate CA
decreased libido, erectile dysfunction, gynecomastia, reduced muscle mass, hot flashes
alternative to castration

138
Q

leucovorin

A

antidote for CA dose of methotrexate to salvage healthy cells

139
Q

emtricitabine/tenovir

A

backbone of other HIV tx
common: N/D, rash, dyslipidemia, fat redistribution, osteoporosis
rare: acute renal failure, peripheral neuropathy, pancreatitis
BBW 1: fatty liver dz that manifests as lactic acidosis
BBW 2: hep B exacerbation; test b4 initiating tx

140
Q

efavirenz

A

HIV NNRTI
self-resolving skin rash
CNS effects: depression, paranoia, aggression, euphoria, hallucinations, sedation
taken at night on empty stomach to reduce CNS effects

141
Q

rilpivirine

A

HIV NNRTI
take w/food
depression, dizziness (less serious than efavirenz)
prolonged QT interval

142
Q

elvitegravir/cobicistat

A

HIV INSTI/CYP inhibitor
take w/food
D/N
CNS effects: depression, paranoia, aggression, euphoria, hallucinations, sedation

NUR 409 Pharmacotherapeutics (38 decks)

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