BPH Flashcards
1
Q
BPH mechanism of action
A
enlarged prostate pinches/impinges urethra
2
Q
BPH meds
A
alpha1 blockers:
tamsulosin
doxazosin
5 alpha reductase inhibitors:
finasteride
dutasteride
herbal:
saw palmetto - not particularly effective
3
Q
alpha 1 blockers mechanism and issues
A
cause relaxation of bladder neck
nonselective: hypoTN, dizziness, nasal congestion, sleepiness
selective agents: abnl ejaculation
4
Q
5 alpha reductase inhibitor mechanism
A
block enzyme which converts testosterone to DHT–> shrinked prostate, discontinues male patterned baldness
5
Q
issues w/5 alpha reductase inhibitors
A
pregnancy category X - wear gloves
men on meds cannot donate blood
decreased libido, abnl ejaculation
falsely decrease prostate specific antigen (PSA) levels - checked for prostate CA
