Histology of the Thyroid Gland Flashcards
Thyroid
Shaped like an H
Consists of two lobes connected by an isthmus extending over the second and third cartilaginous rings of trachea in the neck
Only gland to store the hormone products untill needed
30 million indv follicles in the human thyroid gland
Connective tissue septa
Divides the tissue into discrete lobules
Follicular cells
Hormon producing cells that make up the lobules
Secrete throglobulin into the colloid, where it is stored until thyroid stimulating hormone from the pituitary prompts release of thyroid hormones into the bloodstream
Colloid
Fluid like substance, that follicular cells enclose
Monoiodothyronine and Diiodothronine
Contain one and two iodine mokescules and are physiologically inactive
Triodothronine and Tetraiodothronine
Three or four iodine molecules, are secreted into the blood stream to exter their stimulatory actions on the metabolic rate
Size of follicle cells
Directly relatd to their metabolic activity and rate of hormone of secretion
Active follicles
Columnar follicular cells, with reduced volume of stored colloid material
Less active (resting) follicles
Cuboidal to squamous follicular cells, surround an abundance of stored colloid
Follicle cells
Surrounded by delicate reticular network that includes an extensive capillary bed and lymphatic plexu
Parafollicular cells
small group of pales cells
responsible for the release of calcitonin into the bloodstream
Secreted in response to abnormally high blood calcium lvls and acts to increase excretion of excess calcium in the urine
Parathyoid hormone
opposes this action, serving to raise blood calcium lvls by stimulating the release of calcium from the bones and inhibiting excretion of calcium in the urine