Exam 3: Mannheimia hemolytica, Bibersteinia, Haemophilus, and Histophilus Flashcards
Mannheimia hemolytica used to be:
Pasteurella hemolytica
What are the capsule types of M. hemolytica
A-F
Does M. hemolytica survive well in the environ.
no
VF of M. hemolytica
- Leukotoxin
- Transferrin binding p
- capsule
- endotoxins (LPS)
- Fimbriae
What does M. hemolytica cause in ruminants
pneumonia
Which serovars of M. hemolytica do sheep get
All of them
what serovars of M. hemolytica do cows get
1, 2, 6
Where is M. hemolytica commonly found in sheep
nose
What causes Bacterial broncho pneumonia in calves
M. hemolytica
What is the triggor for Bronchopneumonia in calves
Stress
Where does M. hemolytica replicate in calf
nasopharynx
What is a secondary pathogen of bronchopneumonia in calves
P. multocida
How do you Dx M. haemolytica
Culture
How do you tx M. haemolytica
Abx and corticosterroids
Who becomes infected with Bibersteinia trehalosi
sheep
what does B. trehalosi cause in sheep
Septicaemiae
DDx of Bibersteinia trehalosi
Clostridium perfringens enterotoxemia
What are the cause of B trehalosi
Stress
Haemophilus is ___ dependent meaning stapph. is necessary for culture
NAD
Haemophilus are commensals where?
Mucosae of resp. and repro tract
VF of Haemophilus
- Endotoxin
- Fimbrae
- Neuroamidase
- TBP
What is the disease caused by H. parasuis
Glasser dz
what does glasser dz cause in pigs
- septicemia
- meningitis
- polyserositis
How do you tx glasser dz
antimicrobials
how do you prevent glasser dz
vacc.
What does H. felis cause in cats?
Chronic pneumonia and conjunctivitis
How do you incubate Histophilus somnei
incubate 2 days with 5-10% CO2
where does H. somnei colonize
Mucosal surfaces of ruminants
C/S of H. somnei
Septicemia CNS Arthritis conjunctivits Myocarditis Pneumonia
VF of H. somnei
- LOS
- OMPs
- Host cell interaction
- Biofilms
Which VF of H. somnei is used in activation of caspases and induction of apoptosis
Host cell interaction
WHich VF of H. somnei cause immune evasion and complement resistance
LOS (Lippligosaccharides)
What are the two OMP VFs of H. somnei
- Transferrin binding proteins
2. Ig binding proteins
How do you Dx H. somnei
Bacterial culture
How do you Tx H. somnei
Abx
How do you prevent H. somnei
vacc.