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Bacteriology > Exam 2: Rickettsia, Chlamydia, and Coxiella > Flashcards

Exam 2: Rickettsia, Chlamydia, and Coxiella Flashcards

1
Q

What are the 2 genera in the family Rickettsiaceae

A
  1. Rickettsia

2. Orientia

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2
Q

_____ are arthropod transmitted parasites of blood cells or endothelial cells and may cause persistent infections

A

Rickettsia

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3
Q

Small, obligate intracelluular bacteria that reside freely within the cytoplasm of the infected host cell

A

Rickettsia

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4
Q

T/F rickettsia are Gram positive coccobacilli

A

F. gram neg.

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5
Q

What are reservoirs for Rickettsia

A

rodents and sm. mammals

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6
Q

How do animals become infected with rickettsia?

A

arthropod bite

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7
Q

What are the 2 groups of Rickettsia

A
  1. Typhus group (TG)

2. Spotted fever group (SFG)

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8
Q

What are the two spp of ricketsia in the typhus group?

A
  1. R. prowazekii

2. R. typhi

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9
Q

Which Spp of rickettsia is isn the Spotted fever group?

A

R. rickettsii

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10
Q

Rickettsial isolation is performed in BSL __ laboratories

A

3

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11
Q

Dx of rickettsia

A

Direct detection
PCR
Serology Culture

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12
Q

Tx of rickettsia

A

Tetracycline
Doxycycline
Chloramphenicol
Enrofloxacin

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13
Q

Cause of rocky mtn. spotted fever in humans and dogs

A

R. rickettsia

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14
Q

What is the pathogenecis of R. rickettesia

A

invades and repicates in endothelial cells of blood vessels, initiating platelet activation

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15
Q

C/S of R. rickettsia

A 
Fever
Depression
Anorexia
SQ Edema
Stiff gait
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16
Q

Tx of R. rickettsia

A

Tetracycline

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17
Q

Type of Rickettsia causing Epidemic typhus, spread by human and flying squirrel luse

A

R. prowazekii

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18
Q

Type of rickettsia causing murine typhus

A

R. typhi

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19
Q

What is the cycle of importance for R. typhi spread?

A

opossum flea cycle

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20
Q

Rikettsia transmitted by the cat flea and causes inapparent infection in the cat

A

R. felis

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21
Q

What does Rickettsia felis cause in humans?

A

Flea-borne spotted fever

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22
Q

Rickettsia that is transmitted by chigger mites and causes scrub typhys

A

orientia tsutsugamshi

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23
Q

Type of rickettsia that infects Farmed fish

A

Piscirickettsia salmonis

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24
Q

which species of tick transmitts Anaplasma phagocytophilum

A

Ixodes

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25
Q

What does Anaplasma phagocytophilum cause in dogs

A

canine granulocytic ehrlichiosis

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26
Q

Anaplasma that causes infectious cyclic thromboytopenia

A

A. platys

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27
Q

What cells become infected with Anaplasma playts

A

Platlets

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28
Q

How do you Dx Anaplasma playts

A

Blood smear
FA
PCR

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29
Q

Tx for Anaplasma playts

A

Doxycycline

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30
Q

What are the target cells for Anaplasma marginale

A

Erythrocytes

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31
Q

What ssp of Anaplasma causes anaplasmosis in ruminants?

A

A. marginale

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32
Q

T/F. Calves are much more resistant to Anaplasma marginale than adults

A

T

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33
Q

Tx of Anaplasma marginale

A

Tetracycline and imidocarb

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34
Q

Ehrlichia canis causes what disease in dogs?

A

Canine monocyclic ehrlichiosis (CME)

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35
Q

What cells does Ehrlichia canis infect?

A

Forms a cluster of bacteria within the cytoplasm of the monocyte

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36
Q

Ehrlichia canis is transmitted by _____

A

Rhipichephalus sanguineus (brown dog tick)

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37
Q

What are the two phases of the pathogenesis of CME?

A

acute and chronic

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38
Q

T/F CME is associated with lymphadenopathy and splenomegaly

A

T

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39
Q

______ on CBC typifies the severe chronic form of ehrlichiosis due to hypoplasia of alll bone marrow cells

A

Pancytopenia

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40
Q

Dx of Ehrlichia canis

A

IFA
SNAP
PCR

41
Q

Tx of Ehrlichia canis

A

Doxycycline

42
Q

Type of Ehrlichia that cause granulocytic ehrlichiosis in ppl and dogs

A

E. ewingii

43
Q

Which tick transmitts Ehrlichia ewingii

A

Amblyomma americanum

44
Q

Which type of ehrlichia causes human monocytic ehrlichiosis

A

E. chaffeensis

45
Q

Whic tick transmits Ehrlichia chaffeensis

A

Amblyomma americanum

46
Q

Type of Ehrlichia that causes Heart water Dz

A

E. ruminantium

47
Q

T/F E. ruminantium is a reportable dz in the USA

A

T

48
Q

Where does Ehrlichia ruminantium replicate

A

Macrophages and endothelial cells

49
Q

What is the tick vector of Ehrlichia ruminantium?

A

amblyomma amercanum

50
Q

What are the c/s of Ehrlichia ruminantium?

A

Resp and neuro signs

51
Q

how do you dx Ehrlichia ruminantium?

A

brain squash smear

52
Q

Tx of ehrlichia ruminantium?

A

Tetracycline

53
Q

What Spp of neorickettsia causes potomac horse fever

A

N. risticii

54
Q

which cells become infected with neorickettsia risticii

A

Enterocytes and monocytes

55
Q

Neorickettsia risticii is a seasonal dz. In which months do you see it?

A

June - oct.

56
Q

What are the vectors of neorickettsia risticii?

A

Snails and trematodes

57
Q

C/S of Neorickettsia risticii

A

fever, anorexia, leukopenia, D+, laminitis, abortion

58
Q

T/F there is a vacc. available for N. risticii

A

T

59
Q

Type of Neorickettsia that causes salmon poisoning in dogs

A

N. helminthoeca

60
Q

What is the IH of neorickettsia helminthoexa

A

snails and flukes (N salmoncola)

61
Q

What type of Neorickettsia can a dog get by ingesting a salmon infected with N. salmoncola

A

N. helminthoeca

62
Q

What cells become infected with Neorickettsia helminthoeca

A

Monocytes and macrophages

63
Q

C/S. of Neorickettsia helminthoeca

A

Fever, depression, anorexia, V+, hemorhhagic D+, lymphadenopathy

64
Q

In neorickettsia helminthoeca, lesions in the intestines appear and are associatid with _____ tissue

A

Lymphoid

65
Q

Dx of Neorickettsia helminthoeca

A

Fluke eggs in feces

66
Q

What is the DD of neorickettsia helmintoeca

A

Parvo

67
Q

Tx of Neorickettsia helminthoeca

A

Tetracycline and praziquantel

68
Q

Is chlamydia an intra/extracellular pathogen?

A

Obligate intracellular

69
Q

which cells become infected with chlamydia

A

Epithelial cells

70
Q

What type of lifecycle dos chlamydia have

A

Dimorphic

71
Q

What are the 2 parts of the dimorphic life cycle of chlamydia

A
  1. reticulate body: intracellular replicating form

2. Elementary body: Extracellular non-rep. form

72
Q

Which form of chlamydia can survive outside of the host?

A

Elementary body

73
Q

Chlamydia are known as energy parasites because____ they do not generate ATP

A

they do not generate ATP

74
Q

Which spp of chlamydia is zoonotic?

A

C. psittachi

75
Q

What are the 3 major chlamydial diseases in humans?

A

C. psittachi
C. trachomatis
C. pneumonia

76
Q

Avian chlamydiosis

A

C. psittachi

77
Q

human chlamydiosis

A

C. trachomatis

78
Q

Chlamida in humans and koalas that causes conjunctivitis, pneumonitis, abortion and arthritis

A

C. pneumonia

79
Q

what are the 4 ways you can dx chlamydia

A
  1. microscopic detection by cytologic exam
  2. culture
  3. serology
  4. PCR
80
Q

What chlamydial diagnostic tool would you use to detect carriers

A

PCR

81
Q

Causes avian chlamydiosis

A

C. psittaci

82
Q

Chlamydia psittaci is a BSL __

A

3

83
Q

T/F. Chlamydia psittaci is a zoonotic disease but is not reportable

A

F. also reportable

84
Q

Tx for Chlamydia psittaci

A

tetracycline

85
Q

T/F. there is a vacc. available for Chlamydia psittaci

A

F

86
Q

What does Chlamydia abortus cause in ruminants

A

Enzootic abortion of ewes

87
Q

type of chlamydia that causes polyarthritis is lambs and calves

A

C. pecorum

88
Q

What two diseases does Chlamydia pecorum cause?

A

Stiff lamb dz

Sporadic bovine encephalomyelitis (SBE)

89
Q

Chlamidial spp. that is a known agent of feline pneumonitis

A

C. felis

90
Q

What are the most common signs of Chlamydia felis infection?

A
  1. Conjunctivits

2. Rhinitis

91
Q

What is the bacteria that causes Queensland fever?

A

Coxiella burnetii

92
Q

T/F Coxiella burnetii is an obligate extracellular pathogen.

A

F. intracellular

93
Q

What spp. are susceptible to Coxiella burnetii infection?

A

Ruminants and humans

94
Q

Why is coxiella burnetii a difficult pathogen to control?

A

endospore- like form persistent in environ

95
Q

T/F. Coxioella burnetii subclinically persists in carrier males.

A

F. Females

96
Q

T/F Coxiella burnetii is released in massive quantities areound partrition

A

T

97
Q

T/F. there is a vacc. for cattle against coxiella burnetii

A

F. vacc for humans

98
Q

What does subclinical Coxiella burnetii dz cause in pregnant animals

A

abortion and placentitis

99
Q

How do you tx coxiella burnetii

A

tetracycline and fluoroquinolones

Bacteriology (31 decks)

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