Exam 3: Bordetella Flashcards

1
Q

What are the 4 spp. of Bordetella we learned about

A

B. bronchiseptica
B. avium
B. pertussis
B. parapertussis

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2
Q

What 2 spp. of Bordetella cause whooping cough

A

B. pertussis

B. parapertussis

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3
Q

B. bronchiseptica has an affinity for ____

A

ciliated resp. epithelium

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4
Q

What does B. bronchiseptica cause in dogs

A

Kennel cough

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5
Q

What does B. bronchiseptica caue in pigs

A

Atrophic rhinitis

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6
Q

VF. of B. bronchiseptica

A

Adhesions
biofilms
Toxins
Bvg regulation

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7
Q

What are the 4 major toxins of B. bronchiseptica

A
  1. Hemolysin
  2. Dermonecrotic toxin
  3. Osteo toxin
  4. Tracheal cytotoxin
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8
Q

Which B. bronchiseptica toxin inhibits the function of neutrophils and forms pores

A

Hemolysin

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9
Q

Which B. bronchiseptica toxin causes skin necrosis which damages nasal tissue and osteoblasts

A

Dermonecrotic toxin

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10
Q

Which B. bronchiseptica toxin is toxic for osteoblasts

A

Osteo toxin

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11
Q

Which B. bronchiseptica toxin Destroys Ciliated resp. epithelium

A

Tracheal cytotoxin

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12
Q

what is the importance of BVG regulation

A

phase variation

determines virulence

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13
Q

What are the 3 diseases caused by B. bronchiseptica in pigs

A
  1. non progressive atropic rhinitis
  2. Pneumonic bordetellosis
  3. Progressive atrophic rhinitis
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14
Q

What toxin is inc. in non progressive atropic rhinitis

A

Dermonecrotic toxin

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15
Q

What aged pigs become infected with primary pneumonic bordetellosis

A

less than 1 wk

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16
Q

What aged pigs become infected with secondary pneumonic bordetellosis

A

over 1 wk

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17
Q

C/S of pneumonic bordetellosis

A

cough
dyspnea
no fever

18
Q

Where are lesions asociated with pneumonic bordetellosis commonly found?

A

Lungs

19
Q

What two bacteria cause Progressive atrophic rhinits

A

P. multocida

B. bronchiseptica

20
Q

DNT productio of P. multocida causes and inc in ______

A

osteoclasts

21
Q

T/F. Bordetella colonizes easier than P. multocida

A

T

22
Q

how is Progressive atrphic rhinitis spread

A

direct contact

23
Q

C/S of PRogressive atrophic rhinitis

A
  1. Sniffling
  2. sneezing
  3. Tears
  4. Bloody discharge
24
Q

How do you Tx progressive atrophic rhinitis

A
Difficult
combination of:
1. hygiene
2. Antibacterial
3. Vacc. of piglets
25
Q

How do you Dx Progressive Atrophic rhinitis

A
  1. cutivation
  2. Serology
  3. PCR
26
Q

Bordetella bronchiseptica is naturally resistant to what 4 meds?

A
  1. Nitrofurantoin
  2. Spectinomycin
  3. Ceftiofur
  4. Amoxy
27
Q

B. bronchiseptica has acquired resistance to ____

A

sulfonamides

28
Q

What is canine infectious tracheobronchitis

A

kennel cough

29
Q

What are the agents that cause kennel cough

A
  1. CPV
  2. CAV 1 and 2
  3. CHV 1
  4. Reovirus 1, 2, 3
  5. Mycoplasma cynos
30
Q

What are the two types of Kennel cough infections

A

Endogenic

exogenic

31
Q

C/S of kennel cough

A

Dry cough
nasal secretions
anorexia

32
Q

Why is there a long excretion of kennel cough

A

slow development of local abs.

33
Q

How do you Dx Kennel cough

A
  1. Isolation

2. BAL

34
Q

What abx can be used to tx kennel cough

A

Tetracyclines

35
Q

How do you prevent horses from getting kennel cough

A

Prevent inhalation of fungal spores

36
Q

What is B.avium infection in turkeys called

A

Coryza

37
Q

What does B. avum cause in turkeys

A

rhinotracheitis

38
Q

What viruses also cause Coryza in turkeus

A

TRT virus

E. coli and more

39
Q

C/S of B. avium

A
  1. Dec. growth
  2. Sneezing
  3. head shaking
40
Q

How do you prevent B avium

A

hygiene
dont mix ages
vacc.

41
Q

T/F Bordetella is only zoonotic in immunocompromised ppl

A

T