Exam 3: Bordetella Flashcards
What are the 4 spp. of Bordetella we learned about
B. bronchiseptica
B. avium
B. pertussis
B. parapertussis
What 2 spp. of Bordetella cause whooping cough
B. pertussis
B. parapertussis
B. bronchiseptica has an affinity for ____
ciliated resp. epithelium
What does B. bronchiseptica cause in dogs
Kennel cough
What does B. bronchiseptica caue in pigs
Atrophic rhinitis
VF. of B. bronchiseptica
Adhesions
biofilms
Toxins
Bvg regulation
What are the 4 major toxins of B. bronchiseptica
- Hemolysin
- Dermonecrotic toxin
- Osteo toxin
- Tracheal cytotoxin
Which B. bronchiseptica toxin inhibits the function of neutrophils and forms pores
Hemolysin
Which B. bronchiseptica toxin causes skin necrosis which damages nasal tissue and osteoblasts
Dermonecrotic toxin
Which B. bronchiseptica toxin is toxic for osteoblasts
Osteo toxin
Which B. bronchiseptica toxin Destroys Ciliated resp. epithelium
Tracheal cytotoxin
what is the importance of BVG regulation
phase variation
determines virulence
What are the 3 diseases caused by B. bronchiseptica in pigs
- non progressive atropic rhinitis
- Pneumonic bordetellosis
- Progressive atrophic rhinitis
What toxin is inc. in non progressive atropic rhinitis
Dermonecrotic toxin
What aged pigs become infected with primary pneumonic bordetellosis
less than 1 wk
What aged pigs become infected with secondary pneumonic bordetellosis
over 1 wk
C/S of pneumonic bordetellosis
cough
dyspnea
no fever
Where are lesions asociated with pneumonic bordetellosis commonly found?
Lungs
What two bacteria cause Progressive atrophic rhinits
P. multocida
B. bronchiseptica
DNT productio of P. multocida causes and inc in ______
osteoclasts
T/F. Bordetella colonizes easier than P. multocida
T
how is Progressive atrphic rhinitis spread
direct contact
C/S of PRogressive atrophic rhinitis
- Sniffling
- sneezing
- Tears
- Bloody discharge
How do you Tx progressive atrophic rhinitis
Difficult combination of: 1. hygiene 2. Antibacterial 3. Vacc. of piglets
How do you Dx Progressive Atrophic rhinitis
- cutivation
- Serology
- PCR
Bordetella bronchiseptica is naturally resistant to what 4 meds?
- Nitrofurantoin
- Spectinomycin
- Ceftiofur
- Amoxy
B. bronchiseptica has acquired resistance to ____
sulfonamides
What is canine infectious tracheobronchitis
kennel cough
What are the agents that cause kennel cough
- CPV
- CAV 1 and 2
- CHV 1
- Reovirus 1, 2, 3
- Mycoplasma cynos
What are the two types of Kennel cough infections
Endogenic
exogenic
C/S of kennel cough
Dry cough
nasal secretions
anorexia
Why is there a long excretion of kennel cough
slow development of local abs.
How do you Dx Kennel cough
- Isolation
2. BAL
What abx can be used to tx kennel cough
Tetracyclines
How do you prevent horses from getting kennel cough
Prevent inhalation of fungal spores
What is B.avium infection in turkeys called
Coryza
What does B. avum cause in turkeys
rhinotracheitis
What viruses also cause Coryza in turkeus
TRT virus
E. coli and more
C/S of B. avium
- Dec. growth
- Sneezing
- head shaking
How do you prevent B avium
hygiene
dont mix ages
vacc.
T/F Bordetella is only zoonotic in immunocompromised ppl
T