Exam 3: Bordetella Flashcards

1
Q

What are the 4 spp. of Bordetella we learned about

A

B. bronchiseptica
B. avium
B. pertussis
B. parapertussis

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2
Q

What 2 spp. of Bordetella cause whooping cough

A

B. pertussis

B. parapertussis

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3
Q

B. bronchiseptica has an affinity for ____

A

ciliated resp. epithelium

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4
Q

What does B. bronchiseptica cause in dogs

A

Kennel cough

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5
Q

What does B. bronchiseptica caue in pigs

A

Atrophic rhinitis

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6
Q

VF. of B. bronchiseptica

A

Adhesions
biofilms
Toxins
Bvg regulation

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7
Q

What are the 4 major toxins of B. bronchiseptica

A
  1. Hemolysin
  2. Dermonecrotic toxin
  3. Osteo toxin
  4. Tracheal cytotoxin
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8
Q

Which B. bronchiseptica toxin inhibits the function of neutrophils and forms pores

A

Hemolysin

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9
Q

Which B. bronchiseptica toxin causes skin necrosis which damages nasal tissue and osteoblasts

A

Dermonecrotic toxin

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10
Q

Which B. bronchiseptica toxin is toxic for osteoblasts

A

Osteo toxin

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11
Q

Which B. bronchiseptica toxin Destroys Ciliated resp. epithelium

A

Tracheal cytotoxin

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12
Q

what is the importance of BVG regulation

A

phase variation

determines virulence

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13
Q

What are the 3 diseases caused by B. bronchiseptica in pigs

A
  1. non progressive atropic rhinitis
  2. Pneumonic bordetellosis
  3. Progressive atrophic rhinitis
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14
Q

What toxin is inc. in non progressive atropic rhinitis

A

Dermonecrotic toxin

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15
Q

What aged pigs become infected with primary pneumonic bordetellosis

A

less than 1 wk

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16
Q

What aged pigs become infected with secondary pneumonic bordetellosis

A

over 1 wk

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17
Q

C/S of pneumonic bordetellosis

A

cough
dyspnea
no fever

18
Q

Where are lesions asociated with pneumonic bordetellosis commonly found?

19
Q

What two bacteria cause Progressive atrophic rhinits

A

P. multocida

B. bronchiseptica

20
Q

DNT productio of P. multocida causes and inc in ______

A

osteoclasts

21
Q

T/F. Bordetella colonizes easier than P. multocida

22
Q

how is Progressive atrphic rhinitis spread

A

direct contact

23
Q

C/S of PRogressive atrophic rhinitis

A
  1. Sniffling
  2. sneezing
  3. Tears
  4. Bloody discharge
24
Q

How do you Tx progressive atrophic rhinitis

A
Difficult
combination of:
1. hygiene
2. Antibacterial
3. Vacc. of piglets
25
How do you Dx Progressive Atrophic rhinitis
1. cutivation 2. Serology 3. PCR
26
Bordetella bronchiseptica is naturally resistant to what 4 meds?
1. Nitrofurantoin 2. Spectinomycin 3. Ceftiofur 4. Amoxy
27
B. bronchiseptica has acquired resistance to ____
sulfonamides
28
What is canine infectious tracheobronchitis
kennel cough
29
What are the agents that cause kennel cough
1. CPV 2. CAV 1 and 2 3. CHV 1 4. Reovirus 1, 2, 3 5. Mycoplasma cynos
30
What are the two types of Kennel cough infections
Endogenic | exogenic
31
C/S of kennel cough
Dry cough nasal secretions anorexia
32
Why is there a long excretion of kennel cough
slow development of local abs.
33
How do you Dx Kennel cough
1. Isolation | 2. BAL
34
What abx can be used to tx kennel cough
Tetracyclines
35
How do you prevent horses from getting kennel cough
Prevent inhalation of fungal spores
36
What is B.avium infection in turkeys called
Coryza
37
What does B. avum cause in turkeys
rhinotracheitis
38
What viruses also cause Coryza in turkeus
TRT virus | E. coli and more
39
C/S of B. avium
1. Dec. growth 2. Sneezing 3. head shaking
40
How do you prevent B avium
hygiene dont mix ages vacc.
41
T/F Bordetella is only zoonotic in immunocompromised ppl
T