Exam 1: Gram Positive Bacillus Flashcards

1
Q

Large square - end gram + rods in chains

A

Bacillus

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2
Q

T/F Bacilli can be aerobes or facultative anaerobes

A

T

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3
Q

Are Bacillus Catalase + or -?

A

+

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4
Q

Are Bacillus oxidase + or -?

A

-

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5
Q

Are Bacillus motile or non-motile

A

Motile except B. anthracis

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6
Q

Where is bacillus found?

A

soil

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7
Q

T/F. Most Bacillus species are non-pathogenic environmental organisms

A

T

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8
Q

What is the most important species of Bacillus?

A

Bacillus anthracis

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9
Q

The most durable type of cell found in nature

A

Endospores

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10
Q

T/F. Endospores are produced extracellularly

A

F. produced intracellularly and excreted extra.

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11
Q

What are the 2 major virulence factors of Bacillus anthracis?

A
  1. capsule

2. tripartie anthrax toxin

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12
Q

What is the Bacillus anthracis capsule made up of and what is its function?

A

polymers of D-glutamic acid, anti-phagocytic

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13
Q

What are the 3 proteins encoded on pXO1 for anthrax toxin?

A
  1. Protective antigen (PA)
  2. Edema factor (EF)
  3. Lethal Factor (LF)
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14
Q

Anthrax toxin protein thatis responsible for necrosis and hemorrhage

A

LF

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15
Q

Anthrax toxin protien responsible for edema

A

EF

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16
Q

Anthrax toxin protein responsible for translocation into cell

A

Protective antigen

17
Q

List the predisposing factors that inc. exposure of animals to anthrax

A
  1. History of anthrax deaths
  2. Soil conditions (pH>6, Rich in Ca and N, inc. moisture)
  3. Warm temp
  4. Flooding and evaporation cycles
  5. Drought conditions
18
Q

What are the 3 species of bacillus that are important for vet med?

A
  1. Bacillus anthracis
  2. Bacillus cereus
  3. Bacillus licheniformis
19
Q

What species of animals are affected by Bacillus anthracis

A

Cattle, sheep, pigs, horses

20
Q

Subacute anthrax in horses with localized edema. Septicemia with colic and enteritis

A

Bacillus anthracis

21
Q

Which species acquire per acute septicemia when infected with anthrax

A

cattle

22
Q

WHich species acquire acute septicemia when infected with anthrax

A

Horse

23
Q

List some c/s of per acute septicemia in ruminants infected with Bacillus anthrax

A
  1. Bleeding from orfices
  2. dark unclotted blood
  3. incomplete rigor mortis
  4. splenomegaly
24
Q

T/F. Anthrax is an obligatory reportable disease.

A

T

25
Q

What are the 4 routes of infection of anthrax in humans?

A
  1. cutaneous
  2. intestinal
  3. pulmonary
  4. injection