Exam 3: Actinomyces Flashcards

1
Q

Actinomyces are G+, ___ shaped rods with filamentous branching

A

Club

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2
Q

Are Actinomyces aerobic or anaerobic

A

Aerobic, anaerobic, and capnophilic (require CO2)

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3
Q

T/F. Actinomyces are non spore forming

A

T

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4
Q

Actinomyces characteristically form micorcolonies in the center of lesions, surrounded by _____

A

Macrophages

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5
Q

T/F. Actinomyces are non-motile

A

T

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6
Q

Actinomyces are commensals of ___

A

oral cavity

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7
Q

Where do Actinomyces colonize?

A

mucus memb.

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8
Q

T/F. Most actinomyces spp. are part of the normal microbiota of the oral cavity

A

T

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9
Q

T/F. When Actinomyces cause disease, it is an Acute progressive, pyogranulomatous dz

A

F. Chronic Progressive, pyogranulomatous dz

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10
Q

Pathogenesis of a chronic progressive pyogranulomatous DZ

A
  1. damage of oral mucosa
  2. Spread by direct extension to bones
  3. Chronic infection with bone lysis
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11
Q

What are the 3 spp. of Actinomyces of vet importance?

A
  1. A. bovis
  2. A. viscosus
  3. A. hordeovulneris
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12
Q

Who is the host of Actinomyces bovis, and what does it cause?

A

Bovine

Bovine actinomycosis (lumpy jaw)

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13
Q

Who is the host of Actinomyces viscosus and what does it cause

A

Dog

Canine actinomycosis

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14
Q

Who it the host of Actinomyces hordeovulneris and what does it cause?

A

Dogs

Canine actinomycosis

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15
Q

Pyogranulomatous osteomyelitis in cattle

A

Lumpy jaw

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16
Q

How do cows become infected with lumpy jaw?

A

Actinomyces bovis introduced through penetrating wounds in the oral mucosa

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17
Q

C/S. of lumpy jaw

A
  1. Facial distortion
  2. Loose teeth
  3. dyspnea
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18
Q

Dx. of lumpy jaw

A
  1. C/S
  2. Microscopic exam of granules
  3. Culture
  4. Radiography
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19
Q

Tx of Lumpy jaw

A

Long term high dose penicillin tx

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20
Q

Gram positive filamentous branching bacteria

A

Dermatophilus

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21
Q

Are Dermatophilus aerobic or anaerobic

A

Aerobic

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22
Q

Are dermatophilus mobile

A

Yes

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23
Q

What type of infection does dermatophilus cause

A

Severe infections of traumatized and persistently wet skin with formation of scabs

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24
Q

Where are dermatophilus infections common

A

Tropics

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25
T/F. Dermatophilus are zoonotic
T
26
Factors that inc. likelyhood of dermatophlus infections
1. high humidity 2. High temp. 3. Ectoparasite infection
27
What is the spp. of Dermatophilus that is of vet importance
D. congolensis
28
Dz of cattle, goats, and horses, caused by Dermatophilus congolensis
Cutaneous streptotrichosis
29
Diseases of sheep infected with Dermatophilus congolensis
Lumpy wool | Strawberry footrot
30
Diseases of horses infected with Dermatophilus congolensis
Mud fever | Rain rot
31
Causes exudative dermatitis with scab formation
Dermatophilosis
32
What is the process of Dermatophilosis infection
1. hair mat together 2. crust formation 3. accumulation of cutaneous keratinized lesions
33
3 ways to dx. Dermatophilosis infection
1. C/S 2. Histology of scabs 3. Cytology of scab
34
Which stain would you use to detect Dermatophilosis
Giemsa
35
Tx of Dermatophilosus
1. parenterally Abx | 2. Topical tx
36
Gram +, pleomorphic bacteria that causes suppurative infections
Trueperella
37
T/F. Trueperella are aerobic and capnophilic
T
38
T/F. Trueperella are motile
F
39
T/F. Trueperella are spore forming
F
40
T/F Trueperella are non- capsuled
T
41
Where is Trueperella found?
mucosal memb of GIT
42
T/F. Trueperella survive well in the environ.
T
43
T/F. Trueperella are opportunistic pathogens
T
44
Prevelence of Trueperella is sporadic and governed by what 2 things?
1. Stress | 2. Trauma
45
what are pyolysins?
Hemolytic toxin, cytolytic for neutrophils and macrophages, dermatonecrotic and lethal for lab an.
46
spp. of Truperella that is an important pathogen of cattle
T. pyogens
47
T. Pyogens causes multiple purulent infections with a tendency to causes ____
bacteremia
48
What is summer mastitis?
Mastitis of non-lactating cows and heifers during the summer months
49
Summer mastitis is caused by synergism of what 3 bacterium?
1. Trueperella pyogens 2. Peptostreptococcus indolicus 3. Streptococcus dusgalactiae
50
How is Trueperella pyogens transmitted
Head fly
51
C/S of summer sores
1. Hard, swollen quarter 2. enlarged teat 3. hot 4. thick secretion
52
How do you dx Trueperella infections?
1. smear and gram stain | 2. necropsy and isolation of bacteria
53
Tx of summer mastitis
Penicillin G
54
T/F. there is a vacc. against summer mastitis in cattle
F
55
What is the Actinobaculum spp. of vet importance
A. suis
56
What does actinobaculum look like
Gram positive rods
57
Are Actinobaculum aerobic or anaerobic
anaerobic
58
T/F. Actinobaculum are non-motile
T
59
T/F Actinobaculum are spore forming
F
60
Where is Actinobaculum suis commensal
preputial diverticulum of boars
61
T/F. Actinobaculum suis is a commensal of the urogenital tract of sows
F. not found in healthy sows at all
62
How is Actinobaculum suis transmitted?
sex
63
Causes porcine cystitis and pyelonephritis 3-4 weeks after sex
Actinobaculum Suis