Exam 3: Actinomyces Flashcards
Actinomyces are G+, ___ shaped rods with filamentous branching
Club
Are Actinomyces aerobic or anaerobic
Aerobic, anaerobic, and capnophilic (require CO2)
T/F. Actinomyces are non spore forming
T
Actinomyces characteristically form micorcolonies in the center of lesions, surrounded by _____
Macrophages
T/F. Actinomyces are non-motile
T
Actinomyces are commensals of ___
oral cavity
Where do Actinomyces colonize?
mucus memb.
T/F. Most actinomyces spp. are part of the normal microbiota of the oral cavity
T
T/F. When Actinomyces cause disease, it is an Acute progressive, pyogranulomatous dz
F. Chronic Progressive, pyogranulomatous dz
Pathogenesis of a chronic progressive pyogranulomatous DZ
- damage of oral mucosa
- Spread by direct extension to bones
- Chronic infection with bone lysis
What are the 3 spp. of Actinomyces of vet importance?
- A. bovis
- A. viscosus
- A. hordeovulneris
Who is the host of Actinomyces bovis, and what does it cause?
Bovine
Bovine actinomycosis (lumpy jaw)
Who is the host of Actinomyces viscosus and what does it cause
Dog
Canine actinomycosis
Who it the host of Actinomyces hordeovulneris and what does it cause?
Dogs
Canine actinomycosis
Pyogranulomatous osteomyelitis in cattle
Lumpy jaw
How do cows become infected with lumpy jaw?
Actinomyces bovis introduced through penetrating wounds in the oral mucosa
C/S. of lumpy jaw
- Facial distortion
- Loose teeth
- dyspnea
Dx. of lumpy jaw
- C/S
- Microscopic exam of granules
- Culture
- Radiography
Tx of Lumpy jaw
Long term high dose penicillin tx
Gram positive filamentous branching bacteria
Dermatophilus
Are Dermatophilus aerobic or anaerobic
Aerobic
Are dermatophilus mobile
Yes
What type of infection does dermatophilus cause
Severe infections of traumatized and persistently wet skin with formation of scabs
Where are dermatophilus infections common
Tropics
T/F. Dermatophilus are zoonotic
T