Exam 3: Actinomyces Flashcards

1
Q

Actinomyces are G+, ___ shaped rods with filamentous branching

A

Club

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2
Q

Are Actinomyces aerobic or anaerobic

A

Aerobic, anaerobic, and capnophilic (require CO2)

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3
Q

T/F. Actinomyces are non spore forming

A

T

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4
Q

Actinomyces characteristically form micorcolonies in the center of lesions, surrounded by _____

A

Macrophages

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5
Q

T/F. Actinomyces are non-motile

A

T

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6
Q

Actinomyces are commensals of ___

A

oral cavity

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7
Q

Where do Actinomyces colonize?

A

mucus memb.

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8
Q

T/F. Most actinomyces spp. are part of the normal microbiota of the oral cavity

A

T

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9
Q

T/F. When Actinomyces cause disease, it is an Acute progressive, pyogranulomatous dz

A

F. Chronic Progressive, pyogranulomatous dz

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10
Q

Pathogenesis of a chronic progressive pyogranulomatous DZ

A
  1. damage of oral mucosa
  2. Spread by direct extension to bones
  3. Chronic infection with bone lysis
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11
Q

What are the 3 spp. of Actinomyces of vet importance?

A
  1. A. bovis
  2. A. viscosus
  3. A. hordeovulneris
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12
Q

Who is the host of Actinomyces bovis, and what does it cause?

A

Bovine

Bovine actinomycosis (lumpy jaw)

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13
Q

Who is the host of Actinomyces viscosus and what does it cause

A

Dog

Canine actinomycosis

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14
Q

Who it the host of Actinomyces hordeovulneris and what does it cause?

A

Dogs

Canine actinomycosis

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15
Q

Pyogranulomatous osteomyelitis in cattle

A

Lumpy jaw

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16
Q

How do cows become infected with lumpy jaw?

A

Actinomyces bovis introduced through penetrating wounds in the oral mucosa

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17
Q

C/S. of lumpy jaw

A
  1. Facial distortion
  2. Loose teeth
  3. dyspnea
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18
Q

Dx. of lumpy jaw

A
  1. C/S
  2. Microscopic exam of granules
  3. Culture
  4. Radiography
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19
Q

Tx of Lumpy jaw

A

Long term high dose penicillin tx

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20
Q

Gram positive filamentous branching bacteria

A

Dermatophilus

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21
Q

Are Dermatophilus aerobic or anaerobic

A

Aerobic

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22
Q

Are dermatophilus mobile

A

Yes

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23
Q

What type of infection does dermatophilus cause

A

Severe infections of traumatized and persistently wet skin with formation of scabs

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24
Q

Where are dermatophilus infections common

A

Tropics

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25
Q

T/F. Dermatophilus are zoonotic

A

T

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26
Q

Factors that inc. likelyhood of dermatophlus infections

A
  1. high humidity
  2. High temp.
  3. Ectoparasite infection
27
Q

What is the spp. of Dermatophilus that is of vet importance

A

D. congolensis

28
Q

Dz of cattle, goats, and horses, caused by Dermatophilus congolensis

A

Cutaneous streptotrichosis

29
Q

Diseases of sheep infected with Dermatophilus congolensis

A

Lumpy wool

Strawberry footrot

30
Q

Diseases of horses infected with Dermatophilus congolensis

A

Mud fever

Rain rot

31
Q

Causes exudative dermatitis with scab formation

A

Dermatophilosis

32
Q

What is the process of Dermatophilosis infection

A
  1. hair mat together
  2. crust formation
  3. accumulation of cutaneous keratinized lesions
33
Q

3 ways to dx. Dermatophilosis infection

A
  1. C/S
  2. Histology of scabs
  3. Cytology of scab
34
Q

Which stain would you use to detect Dermatophilosis

A

Giemsa

35
Q

Tx of Dermatophilosus

A
  1. parenterally Abx

2. Topical tx

36
Q

Gram +, pleomorphic bacteria that causes suppurative infections

A

Trueperella

37
Q

T/F. Trueperella are aerobic and capnophilic

A

T

38
Q

T/F. Trueperella are motile

A

F

39
Q

T/F. Trueperella are spore forming

A

F

40
Q

T/F Trueperella are non- capsuled

A

T

41
Q

Where is Trueperella found?

A

mucosal memb of GIT

42
Q

T/F. Trueperella survive well in the environ.

A

T

43
Q

T/F. Trueperella are opportunistic pathogens

A

T

44
Q

Prevelence of Trueperella is sporadic and governed by what 2 things?

A
  1. Stress

2. Trauma

45
Q

what are pyolysins?

A

Hemolytic toxin, cytolytic for neutrophils and macrophages, dermatonecrotic and lethal for lab an.

46
Q

spp. of Truperella that is an important pathogen of cattle

A

T. pyogens

47
Q

T. Pyogens causes multiple purulent infections with a tendency to causes ____

A

bacteremia

48
Q

What is summer mastitis?

A

Mastitis of non-lactating cows and heifers during the summer months

49
Q

Summer mastitis is caused by synergism of what 3 bacterium?

A
  1. Trueperella pyogens
  2. Peptostreptococcus indolicus
  3. Streptococcus dusgalactiae
50
Q

How is Trueperella pyogens transmitted

A

Head fly

51
Q

C/S of summer sores

A
  1. Hard, swollen quarter
  2. enlarged teat
  3. hot
  4. thick secretion
52
Q

How do you dx Trueperella infections?

A
  1. smear and gram stain

2. necropsy and isolation of bacteria

53
Q

Tx of summer mastitis

A

Penicillin G

54
Q

T/F. there is a vacc. against summer mastitis in cattle

A

F

55
Q

What is the Actinobaculum spp. of vet importance

A

A. suis

56
Q

What does actinobaculum look like

A

Gram positive rods

57
Q

Are Actinobaculum aerobic or anaerobic

A

anaerobic

58
Q

T/F. Actinobaculum are non-motile

A

T

59
Q

T/F Actinobaculum are spore forming

A

F

60
Q

Where is Actinobaculum suis commensal

A

preputial diverticulum of boars

61
Q

T/F. Actinobaculum suis is a commensal of the urogenital tract of sows

A

F. not found in healthy sows at all

62
Q

How is Actinobaculum suis transmitted?

A

sex

63
Q

Causes porcine cystitis and pyelonephritis 3-4 weeks after sex

A

Actinobaculum Suis