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Bacteriology > Exam 2: Campylobacter, Helicobacter, Lawsonia > Flashcards

Exam 2: Campylobacter, Helicobacter, Lawsonia Flashcards

1
Q

List two similaraties between campylobacter, helicobacter, and lawsonia

A
  1. Typical gram neg. cell wall

2. opportunistic extracellular pathogens

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2
Q

Curved, motile, gram negative rods

A

Campylobacter

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3
Q

What is the O2 requirement for campylobacter

A

Microaerophilic (low oxygen required so dont survive well in the environment

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4
Q

Where is campylobacter found?

A

GIT and lower genital tract

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5
Q

T/F campylobacter is easy to isolate

A

F. difficult to isolate and need special culture

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6
Q

What are the common campylobacter pathogens?

A
  1. C. fetus subsp. venerealis
  2. C. fetus subsp. fetus
  3. C. jejuni
  4. C. coli, C. upsanliensis
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7
Q

Which spp of campylobacter causes bovine venereal campylobacteriosis

A

C. fetus subsp. venerealis

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8
Q

Which spp. of Calmpylobacter causes early embryonic death?

A

C. fetus subsp. venerealis

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9
Q

Which spp of campylobacter causes bacteraemia and abortions

A

C. fetus subsp. fetus

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10
Q

Which spp. of campylobacter causes gastroenteritis, diarrhea, and bacteremia in all spp.

A

C. jejuni

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11
Q

What does C. jejuni cause in dogs

A

Sporadic gastroenteritis

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12
Q

What does C. jeuni cause in ruminants?

A

Sporadic abortion

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13
Q

What does C. jejuni cause in poultry?

A

sporadic gastroenteritis and hepatitis

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14
Q

Major cause of intestinal illness and D+ in humans and animals

A

C. jejuni

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15
Q

T/F. C. jejuni is common under poor sanitation conditions

A

T

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16
Q

who is most effected by C. jejuni

A

Young

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17
Q

how do people or animals become infected with C. jejuni

A

ingestion of contaminated materials

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18
Q

What syndrome is associated with C. jejuni and what is it?

A

Guillain Barre syndrome: an acute immune-mediated demyelination of peripheral n.

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19
Q

List some major sources of C. jejuni

A

chicken, raw milk, puppies, water, other meats

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20
Q

how is C. jejuni mobile

A

single bipolar flagellum

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21
Q

where does C. jejuni colonize

A

in the GI mucus where it invades the epithelial cells and leads to bacteremia

22
Q

what attributes to D+ in C. jejuni infection

A

Heat labile enterotoxin

23
Q

What attributes to cell cycle arrest in C. jejuni inf.

A

Cytolethal distending toxin (CDT)

24
Q

What are the 4 diseases caused by C. jejuni

A
  1. superficial erosive enteritis
  2. ileitis-colitis (hemorrhagic)
  3. self-limiting enteritis
  4. severe, invasive, bacteremia and abortions
25
Q

How do you Dx c. jejuni

A

Culture of poo

26
Q

How do you tx C. jejuni

A

macrolides, and fluoroquinolones

27
Q

How do you control C. jejuni

A

Hygiene and management

28
Q

Bovine venereal campylobacteriosis

A

Campylobacter fetus subsp. venerealis

29
Q

Campylobacter that causes subclinical infection in the preputial crypts of bulls

A

C. fetus subsp. venerealis

30
Q

What are the c/s of C. fetus subsp. venerealis?

A
  1. Endometritis
  2. salpingitis
  3. transient infertility
  4. early embryonic death
31
Q

How do you Dx C fetus subsp. venerealis in Bulls?

A
  1. Preputial wash or semen
  2. Darkfield microscopy
  3. PCR
  4. Culture
32
Q

How do you Dx C fetus subsp. venerealis in cows?

A
  1. Abs in vaginal mucus

2. Culture (not as sensitive in cows)

33
Q

Tx for C fetus subsp. venerealis

A

Antimicriobials

34
Q

How do you control C fetus subsp. venerealis

A

Breed only test negative bulls and heifers

35
Q

Campylobacter that are commensals in the GIT of ruminants that causes ovine genital campylobacteriosis

A

C fetus subsp. fetus

36
Q

what does C fetus subsp. fetus cause in cattle?

A

occasional abortions

37
Q

small, spirally curved gram - rods present in the GIT

A

Helicobacter

38
Q

T/F helicobacter spp are motile

A

T. bipolar flagellum

39
Q

T/F Helicobacter spp. are anaerobic

A

F. Microaerophilic

40
Q

T/F Helicobacter spp. are gram negative

A

T

41
Q

Helicobacter spp. that is found in the stomach and associated with gastric ulcers and neoplasms

A

H. pylori

42
Q

What are the virulence factors associated with H. pylori

A
  1. adhesins
  2. flagella
  3. endotoxin
  4. extracellular urease
43
Q

Strains of helicobacter that are also found in the stomach of cats and dogs that have been linked to gastritis and ulcers

A

H. canis
H. felis
H. heilmannii

44
Q

Helicobacter spp. that are mouse pathogens involved in hepatic necrosis, nonsupprative hepatitis, and hepatocellular tumors

A

H. hepaticus and H bilis

45
Q

Helicobacter spp involved in hypergastrinemia and peptic ulcers in ferrets

A

Helicobacter mustelae

46
Q

How do you Dx Helicobacter spp?

A
  1. endoscopy
  2. urease breath test
  3. microscopic detection (Serology, PCR)
47
Q

Tx of helicobacter

A

proton pump inhibitors and antimicrobials

48
Q

T/F. it is difficult to control Helicobacter

A

T

49
Q

What are some steps to conrolling helicobacter?

A

Isolate and tx infected animals

test and cull (lab animals)

50
Q

How do you control lawsonia intracellularis infection?

A
  1. live attenuated vacc. in pigs

2. specific pathogen free approaches

Bacteriology (31 decks)

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