EX3 Histology - Female Reproductive System Flashcards
What is the endocrine and exocrine function of the ovaries
endocrine - produce estrogens and progestogens; steriodogenesis
exocrine - produce the female gamete (ovum); gametogenesis; produce and ovulate a secondary oocyte
These promotes the growth and maturation of internal and external sex organs, promotes menstruation and development of secondary sex characteristics
estrogens
These prepare internal sex organs (uterus) for pregnancy by promoting changes in endometrium and mammary glands for lactation
progestones
These are found within the cortex of the ovaries and composed of an oocyte surrounded by one or more layers of epithelium
ovarian follicles
What indicates the developmental state of the oocyte
size of the ovarian follicles
What are the three basic types of ovarian follicles
primordial follicles
growing follicles (primary and secondary)
mature (or Graafian) follicles
What stage of the follicle has squamous epithelium
primordial follicle
In the third month of fetal life, what happens, what stage of meiosis is it stuck
PGCs migrate from yolk sac; the oogenia divide into primary oocyte and rest at prophase of meiosis 1
How many ovarian folic in the fetus? ovulated?
600,000-800,000 at birth
~400 ovulated (lost via atresia)
This is a sheath of connective tissue cells that develop from the stromal cells surrounding the developing follicle; found external to the basal lamina
theca folliculi
The theca follicli differentiates into which two parts
theca interna
theca externa
These are cubodial secretory cells and in response to LH, they synthesize and secrete androgens (estrogen precursor); endocrine; fibroblasts, collagen bundles and lots of vessels
theca interna
This is the fibrous outer portion; smooth muscle cells, fibroblasts, and collagen bundles
theca externa
This is produced by(and is) granular cells; produces follicular fluid and is indicative a secondary follicle
antrum (secondary Antral follicles)
This hormone stimulates follicle cells to grow, increase in size, and the growth of an oocyte
FSH; from pituitary gland
This is made of glycoproteins; vital for sperm attachment
zona pellucide
This is made follicular cells that have grown
stratum granulosum (granulosa cells)
What begins the secondary oocyte
metaphase of meiosis, this will be ovulated
These are the two cells of the corpus luteum
granulosa lutein cells
theca lutein cells
These cells undergo hypertrophy (30μm); centrally located cells derived from granulosa cells; begins to produce progesterone
granulosa leutin cells
These cells slightly increase in size (15μm); peripherally located cells derived from cells of the theca intern; produce estorgens
theca leutin cells
At what stage will the granulosa and theca leutin cells inactivate and lyse
day 14
This is formed from the degeneration of the corpus luteum
corpus albicans
This is a paired muscular tube 12cm in length, where fertilization takes place
uterine (Fallopian) tube
What makes up the wall of the uterine tube
folded mucosa with simple columnar epithelium, thick muscularis (smooth muscle) and serosa
What type of cells are found in the uterine tube
ciliated cells
secretory cells
These cells help move the oocyte toward the uterus
ciliated cells
These cells are dark staining, have apical budges and produce a nutritive fluid covering epithelium
secretory cells
This is the outer connective tissue later (adventitia or serosa) of the uterus
perimetrium
This is the middle thick layer of the uterus made up of bundles of smooth muscle separated by connective tissue and blood vessels; four poorly defined layers
myometrium
This is the inner layer of the uterus made up of simply columnar epithelium with both ciliated and secretory cells with lamina propria; contains uterine glands
endometrium
What are the two parts of the endometrium
basal layer
functional layer
What happens to the functional layer of the endometrium during menstrual flow
it thickens by changes in ovarian hormones and the majority is sloughed away during menstruation
What does the basal layer of the endometrium contain
uterine glands
What type of epithelium is in the vagina
wall; mucosa, muscular, adventitia
mucosa = nonkeratinized stratified squamous epithelium
smooth muscle = inner circular, outer longitudinal
What are the two types of primary oocytes
unilaminar and multilaminar
will see either 1 or 2+ layers