epinephrine Flashcards
Trade names for epinephrine
Adrenalin
Classes for epinephrine
Sympathomimetic
MOA of epinephrine
Vasoconstricion Increases HR Increases myocardial contractility Bronchodilation Block histamine receptors
Indications for epinephrine
Cardiac arrest - Asystole - Pulseless electrical activity - Ventricular fibrillation - Pulsless ventricular tachycardia Asthma Bronchospasm associated with chronic bronchitis and emphysema Allergic reaction Anaphylaxis Bradycardia Hypotension (from a cause other than hypovolemia)
Contraindications for epinephrine
None in the emergency setting
Adverse reactions to epinephrine
Extravasation of the IV/IO may cause tissue necrosis Tachycardia Increased myocardial oxygen demand Hypertension Dysrhythmias Palpitations Chest pain Dyspnea Tremors Nervousness Anxiety Dizziness Headache Nausea / vomiting
Routes of administration for epinephrine
IV IO IM ET Infusion
Onset/Peak/Duration for epinephrine (IV/IO/ET)
O: < 2 minutes
P: < 5 minutes
D: 5-10 minutes
Adult dosages for epinephrine (cardiac arrest)
IV/IO: 1 mg (1:10,000)
May repeat the dose every 3-5 minutes
Pediatric dosages for epinephrine (cardiac arrest)
- 01 mg/kg (1:10,000) IV/IO
- May repeat the dose every 3-5 minutes
Special considerations for epinephrine
Can increase adverse reactions when administered with another sympathomimetic
An infusion pump should be used when possible
Standard supplies for epinephrine
Prefilled syringe Vial Ampule Auto-injectors: Adult EpiPen EpiPen Jr.
Onset/Peak/Duration for epinephrine (IM)
O: 3-10 minutes
P < 20 minutes
D: 20-30 minutes
Adult dosages for epinephrine (bradycardia/hypotension)
2-10 mcg/min infusion
Adult dosages for epinephrine (bronchospasm/anaphylaxis)
IM: 0.3 - 0.5 mg (1:1,000)
Adult auto injector 0.3 mg
