diazepam Flashcards

1
Q

Trade name for diazepam

A

Valium

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2
Q

Classes for diazepam

A

Benzodiazepine
Anticonvulsant
Sedative
Hypnotic

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3
Q

Standard supplies for diazepam

A

Vial

Ampule

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4
Q

Mechanisms of action for diazepam

A

Produces sedation by acting on the limbic system, the thalamus, and hypothalamus
Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
Raises the seizure threshold
Produces tranquilizing (antianxiety) effect on the central nervous system

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5
Q

Indications for diazepam

A

Seizure activity
Status epilepticus
Procedural sedation for rapid sequence intubation and cardioversion
Chemical restraint for agitated (excited) delirium
Delirium tremens
Severe anxiety

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6
Q

Contraindications for diazepam

A

Known hypersensitivity of the drug

Head injury

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7
Q

Adverse reactions of diazepam

A
Sedation
Transient amnesia
Respiratory depression
Respiratory arrest
Bradycardia
Hypotension
Dizziness
Drowsiness
Blurred vision
Nausea
Vomiting
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8
Q

Routes of administration for diazepam

A

IV
IO
IM
Rectal

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9
Q

Adult dosages for diazepam

A

2.0 mg increments over 2 minutes

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10
Q

Pediatric dosages for diazepam

A

IV/IO: 0.2-0.3 mg/kg
IM: 0.1-2.0 mg/kg
Rectal: 0.2-0.5 mg/kg

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11
Q

Special considerations for diazepam

A

Efficacy of rectal administration of the drug to adults has not been established

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12
Q

Onset/Peak/Duration for diazepam (IV/IO)

A

O: 2-5 minutes
P: 15 minutes
D: 15-60 minutes

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13
Q

Onset/Peak/Duration for diazepam (IM)

A

O: 15-30 minutes
P: 30-45 minutes
D: 15-60 minutes

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14
Q

Onset/Peak/Duration for diazepam (Rectal)

A

Variable

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