diazepam Flashcards
Trade name for diazepam
Valium
Classes for diazepam
Benzodiazepine
Anticonvulsant
Sedative
Hypnotic
Standard supplies for diazepam
Vial
Ampule
Mechanisms of action for diazepam
Produces sedation by acting on the limbic system, the thalamus, and hypothalamus
Binds to gamma-amino butyric acid (GABA) benzodiazepine receptors in the brain
Raises the seizure threshold
Produces tranquilizing (antianxiety) effect on the central nervous system
Indications for diazepam
Seizure activity
Status epilepticus
Procedural sedation for rapid sequence intubation and cardioversion
Chemical restraint for agitated (excited) delirium
Delirium tremens
Severe anxiety
Contraindications for diazepam
Known hypersensitivity of the drug
Head injury
Adverse reactions of diazepam
Sedation Transient amnesia Respiratory depression Respiratory arrest Bradycardia Hypotension Dizziness Drowsiness Blurred vision Nausea Vomiting
Routes of administration for diazepam
IV
IO
IM
Rectal
Adult dosages for diazepam
2.0 mg increments over 2 minutes
Pediatric dosages for diazepam
IV/IO: 0.2-0.3 mg/kg
IM: 0.1-2.0 mg/kg
Rectal: 0.2-0.5 mg/kg
Special considerations for diazepam
Efficacy of rectal administration of the drug to adults has not been established
Onset/Peak/Duration for diazepam (IV/IO)
O: 2-5 minutes
P: 15 minutes
D: 15-60 minutes
Onset/Peak/Duration for diazepam (IM)
O: 15-30 minutes
P: 30-45 minutes
D: 15-60 minutes
Onset/Peak/Duration for diazepam (Rectal)
Variable