diltiazem

Question 1

Trade name for diltiazem

Answer 1

Cardizem

Question 2

Classes for diltiazem

Answer 2

Calcium channel blocker

Antidysrhythmic

Question 3

Standard supply for diltiazem

Answer 3

Vial

Question 4

MOA for diltiazem

Answer 4

Slows extracellular calcium ion inlfux across myocardial cell membranes
Slows conduction through the SA node and the AV node
Slows ventricular conduction rates in A-Fib atrial flutter

Question 5

Indications for diltiazem

Answer 5

A-Fib with rapid ventricular rate
Atrial flutter with rapid ventricular rate
Supraventricular tachycardia second-line to administration of adenosine

Question 6

Contraindications for diltiazem

Answer 6

Known hypersensitivity to the drug
Hypotension
MI
Cardiogenic shock
V-Tach
Second and Third degree heart block
Wolff-Parkinson-White (WPW) syndrome
Pediatric Pt

Question 7

Adverse reactions to diltiazem

Answer 7

Hypotension
Dysrhythmias
Bradycardia
Dizziness
Weakness
Headache
Nausea
Vomiting

Question 8

Routes of administration for diltiazem

Answer 8

IV
IO
Infusion

Question 9

Onset/Peak/Duration for diltiazem

Answer 9

O: 2-5 minutes
P: 7 minutes
D: 1-3 hours

Question 10

Adult dosages for diltiazem

Answer 10

0.25 mg/kg (usually 20 mg) over 2 minutes
May repeat the dosage 0.35 mg/kg (usually 25 mg) in 15 minutes

Infusion: 5-15 mg/hr

Question 11

Special considerations for diltiazem

Answer 11

Consider decreasing the dosage for elderly patients
Consider pretreatment with calcium chloride
An infusion pump should be used when possible