electrolyte balance' Flashcards

1
Q

what are chemical compounds that dissociate into ions in H2O

A

electrolytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are electrolytes due to

A

the ions being charged particles which conduct electrical current

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are categories of electrolytes

A

inorganic salts, inorganic/ organic acids and bases, some proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what do electrolytes have increased amounts of

A

osmotic power due to dissociation into at least 2 ions: NaCl, MgCl2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what do electrolytes cause

A

fluid shifts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what do fluid shifts do

A

influences movement of H2O from lesser osmalality to higher osmoality= osmosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are major extracellular ions

A

Na+, Cl— , K+, Ca2+, Mg2+, PO3-

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

where do we get most of our electrolytes from

A

food and water we ingest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how are electrolytes removed from the body

A

by kidneys, liver, skin and lungs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

when does the concentration of electrolytes change

A

only when an individual is growing, gaining weight or losing weight

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

electrolyte balance=

A

salt balance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

roles of electrolytes

A

control fluid movements, provide minerals for excitability, secretory activity and membrane permeability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the most abudant cation in the ECF

A

Na

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the primary role of sodium

A

control ECF volume and water distribution in the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what two things does sodium do

A
  1. exert significant osmotic pressuer
  2. cellular plasma membrane= impermeable to Na
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what follows NaCl

A

water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

when there is a change in plasma Na affects

A

plasma volume, BP, ICF, and IF volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

sodium moves from where to where

A

ECF and body secretions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

~8 L of secretions go into what

A

GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

most people consume 10-20x recommended amount of NaCl, so they need to do what

A

excrete quantities of Na

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

if Na intake is low, what occurs

A

conservation of Na

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Total amount of Na+ in the body determines

A

ECF volume and BP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

sodium concentration is regulated by

A

renin-angiotensin- aldosterone and ANF hormone by controlling Na reabsoprtion and excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

As ECF Na+ Content increases->

A

rise in ecf osmolality -> adh and thirst-> increased H2O Retention & Intake  Reduced Na+ Concentration & Increases ECF volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
As BP is elevated ->
increases Na and H2O excretion
26
elevated BP stretches the right atrium->
ANF secretion-> kidneys increasing urine production by inhibiting Na reabsorption and inhibits ADH effect on DCT/CD and inhibits ADH secretion
27
low BP activates
renin-angiotensin-aldosterone-> increases Na concentration and H2O volume in ECF
28
Overdilution of Blood due to xs H2O consumed post exercise  Mental Confusion, Seizures & Coma solute loss, Water retention (Vomit, Diarrhea, Burned skin, xs Diuretics) if also Water loss = Decreased BV & BP (Circulatory Shock)
hyponatremia
29
Due to xs Aldosterone secretion  Pulmonary Edema & Muscle Convulsions May be caused by Dehydration. Causes thirst, Confusion, Lethargy, Coma
hypernatremia
30
Predominant Anions of the ECF, Accompanies Sodium in ECF
Cl
31
Certain Neurotransmitters allow Cl-- Entry into ICF ->
Inhibits Electrically Excitable cells (Neurons & Skeletal muscle)
32
regulation for Cl
Predominant Cation Na+ - Most important Factor in regulation
33
When Acidosis
Less Chloride accompanies Na+ due to HCO3- reabsorption increases to restore Blood pH to normal = Acid Base Regulation
34
Hypochloremia
Due to xs sweat/diuresis/vomiting/diarrhea. Low salt intake/SIADH (xs retention). May indicate Heart Failure or Addison’s
35
Hyperchloremia
Indication of Dehydration, Also with High blood Na+ (Cushing Syndrome), Kidney disease.
36
Chief Intracellular Cation
K
37
K is critical in what
in determining RMP for Electrically Excitable Cells Role in Depolarization & Hyperpolarization
38
If extracellular K+ concentrations Increase =
Cell Depolarizes
39
If extracellular K+ concentrations decrease=
Cell Hyperpolarizes
40
Regulated by Aldosterone Secretion: elevated K->
Aldosterone Secretion  Increases Na+ reabsorption & K+ secretion (via Na+ - K+ Pump in DCT)
41
Due to xs K+ Secretion due to xs Elevation of Aldosterone, Aldosterone increases rate of K+ Secretion & decreases K+ in Blood. Also due to Insulin Administration, which activates Na+ - K+ Pump, which decreases extracellular K+ Low K+ Levels  Fatigue, Muscle cramps or Temporary Paralysis. Due to water pills/diuretics.
hypokalemia
42
Due to Renal disease = Less Renal Excretion  Intestinal Cramping, Diarrhea & Temporary paralysis.
hyperkalemia
43
Role in Exocytosis (Including Neurotransmitters), Muscle contraction, Regulates AP in Cardiac muscle, Blood Clotting
Ca
44
3 Sites for ECF Calcium regulation
kidneys GI tract bones
45
99% of Ca is where
in bone
46
Regulation of Calcium
Deposit into & Reabsorption from Bone
47
long term regulation of Ca`
Maintaining balance between absorption across Intestine wall & Excretion by Kidneys
48
Ca regulated by 3 hormones
PTH vitamin d calcitonin
49
PTH increases Blood Calcium via
osteoclasts, , Renal tubules resorption, Vitamin D3 (UV light) absorb in SI
50
Calcitonin (C cells) decreases
blood Ca, . Inhibits Osteoclasts, preventing bone breakdown.
51
= Affects PM permeability to Sodium, causing Nerve & Muscle tissue to spontaneous AP  Muscle Tetany
hypocalcemia
52
Prevents depolarization of Nerve & Muscle cells.  Deposit CaCO3 salts in soft tissues  Irritation & Inflammation. Can lead to Cardiac arrhythmias.
hypercalcemia
53
85% in Body = Form of CaPO4 Salts in Bone & Teeth, Rest is in Cells
p
54
role of P
Bind to Lipids, Proteins & Carbohydrates; Components of DNA, RNA, ATP; Regulate Enzyme activity, Act as Buffers
55
regulation of P
Diet low in Phosphate can increase the Rate of Phosphate Reabsorption
56
PTH increases extracellular phosphate levels->
bone reabsorption-> release Ca and phosphate ions into ECF
57
If Phosphate levels in ECF exceed normal, what happens
Calcium & Phosphate ions precipitate as Calcium phosphate salts in soft tissues
58
Due to Vitamin D deficiency, Alcohol abuse  Decreased Blood clotting & WBC function
hypophosphatemia
59
Due to Acute & Chronic Renal Failure, due to decreased Filtrate by Kidneys. Also due to chronic laxative use, Prolonged elevation cause Calcium Phosphate deposit in joints, lungs, kidneys.
hyperphosphatemia
60
Stored in Bones or ICF
Mg
61
Due to Alcohol abuse  Muscle weakness & muscle convulsions. Also Insulin Resistance & Chronic Diarrhea, Severe malnutrition, Diuretic therapy. Cramps.
hypomagnesemia
62
Rare. Due to Renal Failure  Nausea, Hypotension & Low RR. Also due to chronic laxative use, xs ingestion of Antacids, OR Magnesium intake. Prolonged elevation cause Calcium Phosphate deposit in joints, lungs, kidneys. Consequences may include Lethargy, impaired CNS functioning, Coma, Respiratory depression & Cardiac arrest.
hypermagnesemia