Chapter 18 Endocrine Glands Part 4 Flashcards
the pancreas has a mixed blank and blank function
exocrine and endorcrine
where is the location of the pancreas?
inferior to liver
head in midline
tail extends to left upper abdomen
portion of tail extends into retroperitoneum
duodeum wraps around the head
what kind of cells are in the pancreas
acinar cells
acinar cells are
digestive
pancreatic enzymatic secretions go into the intestinal lumen via what and go where
via hepatopancreatic duct and go to the duodenum
what are is the endocrine area in the pancreas
islet of langerhans
what percentage is the islet of langerhans of the pancreas
1-2%
alpha cells make what
glucagon
beta cells make what
insulin
delta cells make what
somatostain
do alpha cells increase of decrease BS
increase
do beta cells increase or decrease BS
decrease
what do the delta cells do to the BS
inhibit both
elevated BS is sensed by
beta cells of islets
elevated BS that is sensed by the beta cells of islets does what
release insulin into the blood
what does insulin promote
uptake of glc by somatic cells and stimulates glc stoage as glycogen in liver
when insulin promotes uptake of glc by somatic cells and stimulates glc storage as glycogen in liver=
decrease in bs level
decreased bs is sensed by
alpha cells of islets
decreased bs once senses by alpha cells causes what
release of glucagon into the blood
what does glucagon promote
breakdown of glycogen from liver and gluconeogenesis
the breakdown of glycogen from liver and glucoeogenesis causes what
increase in BS
diabetes mellitus type 1 is from
inadequate/ lack of insulin production by pancreatic beta cells
what activates glucose transporter receptors on most body cells
insulin
what accumulates to high levels in the blood, as cells are starved for the nutrient
glucose
what are most cases of diabetes mellitus type 1 a result from
an autoimmune destructure of the pancreatic islet cells leading to life-long dependency on insulin and long-term metabolic disorder
what is crucial in managing diabetes mellitus type 1
control of glucose
diabetes mellitus is blank dependent with what link
insulin dependent with autoimmune link
diabetes mellitus type 2 are from what problems
receptor problem vs secretion problem