Citric Acid Cycle and Respiratory Chain

Question 1

from what is FAD formed?

Answer 1

riboflavin (vitamin B2)

Question 2

what does a deficiency of riboflavin cause?

Answer 2

lesions of mucous membranes:

• cracked sore lips and corners of mouth
• similar lesions in genital regions
• tongue swollen, tender, magenta

Question 3

what vitamin does CoA contain?

Answer 3

vitamin B5 = pantothenic acid

Question 4

which chemical agents target the respiratory chain?

Answer 4

• rotenone: insecticide, pesticide

- antimycin: antibiotic

Question 5

what are the 3 large protein complexes that the respiratory chain consists of?

Answer 5

• NADH-Q reductase
• cytochrome reductase
• cytochrome oxidase

Question 6

what does coenzyme A form a high energy bond with?

Answer 6

carboxylic acids e.g. acetate

Question 7

what is the first step of the citric acid cycle?

Answer 7

condensation of the acetyl group of acetyl-CoA with keto acid oxaloacetate

Question 8

what blocks the final step in the respiratory chain by which hydrogen combines with oxygen?

Answer 8

cyanide and carbon monoxide

Question 9

how many ATP molecules are created by oxidation of 1 NADH?

Answer 9

3 ATP

Question 10

how many ATP molecules are created by oxidation of 1 FADH2?

Answer 10

2 ATP