Bloodborne Pathogens Flashcards
What are the viral features of HIV?
+ spherical
+ enveloped
+ RNA
+ retrovirus
What are the steps involved in HIV progression to AIDS?
- exposure to HIV
- seroconversion
- asymptomatic
- persistent generalised lymphadenopathy
- AIDS related clinical features
- AIDS
What is the treatment for AIDS?
+ NRTIs (nucleoside reverse transcriptase inhibitors)
+ NNRTIs (non-nucleoside reverse transcriptase inhibitors)
+ PIs (protease inhibitors)
What are the normal treatment combinations for HIV?
+ 1 NRTI and 1 PI
+ 2 NRTIs and 1 NNRTI
How is viral load measured?
Quantitative NAAT
How is HIV transmitted?
+ via blood/blood products/contaminated needles
+ sexually
+ perinatally
Which type of HIV is the most common?
HIV-1
What are the viral features of HBV?
+ hepadnavirus
+ double-stranded DNA
+ enveloped
What is HBsAg?
surface antigen
What does HBsAg indicate?
infectivity
What is HBcAg?
core antigen
When does HBcAg appear?
Early in infection
What is HBeAg?
pre-core antigen
What does HBeAg indicate?
high transmissibility
What does anti-HBsAg provide?
immunity (appears late)