ANS 3 Flashcards
What are the 3 catecholamine NTs?
+ dopamine
+ adrenaline
+ noradrenaline
What adrenoceptor agonist would you use to treat anaphylaxis?
adrenaline
What adrenoceptor agonist would you use to treat asthma?
salbutamol or salmeterol
What adrenoceptor agonist would you use to induce premature labour?
salbutamol
What adrenoceptor agonist would you use to treat cardiac arrest?
adrenaline
What adrenoceptor agonist would you use to treat cardiogenic shock?
dobutamine
What adrenoceptor agonist would you use to treat hypertension?
clonidine
What adrenoreceptor agonist would you use to treat an upper respiratory tract infection?
phenylephrine
What adrenoceptor antagonists would you use to treat hypertension?
+ prazosin
+ propanolol
+ atenolol
What adrenoceptor antagonists would you use to treat atrial dysrhythmias?
+ propanolol
+ atenolol
What adrenoceptor antagonist would you use to treat benign prostatic hyperplasia?
prazosin
What are the (7) adrenoceptor agonists?
\+ noradrenaline \+ adrenaline \+ phenylephrine \+ clonidine \+ salbutamol \+ salmeterol \+ dobutamine
What are the (5) adrenoceptor antagonist drugs?
\+ phentolamine \+ prazosin \+ propanolol \+ atenolol \+ carvedilol
noradrenalin uptake and degradation is affected by what?
- indirect acting sympathomimetic drugs
- monoamine oxidase (MAO) inhibitors
- uptake inhibitors
what are side effects of salbutamol and salmeterol?
- muscle tremor
- cardiac arrhythmias
how does prazosin help treat benign prostatic hyperplasia?
relaxes bladder neck and prostate capsule by blocking α1 receptors
which drug is short-acting? salbutamol or salmeterol
salbutamol
which drug is long-acting? salbutamol or salmeterol
salmeterol
what is a more prostate specific treatment for benign prostatic hyperplasia?
tamsulosin
drugs that affect catecholamines synthesis
methyldopa
drugs that affect catecholamine release
- indirectly acting on sympathomimetics: amphetamines
- by acting on α2 adrenoreceptors: clonidine
inhibitors of catecholamine uptake
NET inhibitors: cocaine, tricyclic antidepressants
inhibitors of catecholamine metabolic degradation
monoamine oxidase (MAO) inhibitors used in depression