Chapter 6: Development of the Lymphatic System

Question 1

What does APC stand for?

Answer 1

Antigen-Presenting Cell

Question 2

Where to T lymphocytes and B lymphocytes develop?

Answer 2

Thymus and bone marrow, respectively

Question 3

What are the primary lymphoid organs?

Answer 3

Thymus and bone marrow

Question 4

Where do B and T lymphocytes originate from?

Answer 4

Bone marrow

Question 5

What happens to mature B and T lymphocytes?

Answer 5

They settle in the lymph nodes and other lymphoid organs and continually circulate throughout the body to patrol for foreign pathogens/cells

Question 6

What is the process by which T and C cells acquire immune competency?

Answer 6

Rearrangement of gene segments within the developing B and T lymphocytes (occurs before Ag exposure) causing antigen receptors (TCR in T cells and Ab in B cells) to develop on the cell membrane that enable the lymphocyte to recognize and respond to a specific antigen (creates a huge diversity of receptors)

Question 7

After millions of T and B cells have been programmed to recognize and respond to different, potential antigens, what types of mechanisms ensure that T and B cells recognize antigens in context?

Answer 7

Positive and negative selection mechanisms

Question 8

What is the term for T and B cells not binding to self-antigens?

Answer 8

Tolerance

Question 9

Why can giving a baby solid food too early result in food allergies?

Answer 9

Because the body reacts to the solid food as a foreign antigen.