Chapter 5: Innate vs Adaptive Immunity

Question 1

What are the two ways bodies respond to cell injury (including infection)?

Answer 1

1) Innate immunity

2) Adaptive immunity

Question 2

Which type of body response to cell injury (including infection) is quick and involves the broad recognition by PRRs of pathogens and cell damage, includes an inflammatory response, and involves no memory for future response for the same agent.

Answer 2

Innate immunity

Question 3

Which type of response to cell injury (including infection) is slow, involves a customized and targeted response, involves humoral (Ab) and cell-mediated (cytotoxic T cells) mechanisms, and leaves a memory response for strong and rapid actions if exposed to the same agent in the future?

Answer 3

Adaptive immunity

Question 4

What are the key features of innate immunity?

Answer 4

1) Quick response
2) Broad recognition by PRRs of pathogens (through PAMPs) or cell damage (DAMPs)
3) Includes an inflammatory response
4) No memory for future response to the same agent.

Question 5

What does PRRs stand for? In which type of immune response is it important?

Answer 5

Pattern recognition receptors; innate immunity

Question 6

What does PAMPs stand for? What are they?

Answer 6

Pathogen Associated Molecular Patterns; they are pattern recognition receptors that recognize pathogens as a part of innate immunity.

Question 7

What does DAMPs stand for? What are they?

Answer 7

Damage Associated Molecular Patterns; they are PRRs that recognize cell damage as a part of innate immunity.

Question 8

Which types of PRRs recognize cell damage?

Answer 8

DAMPs

Question 9

Which types of PRRs recognize pathogens?

Answer 9

PAMPs

Question 10

What are the key features of adaptive immunity?

Answer 10

1) Slow
2) Customized, targeted response
3) Involves humoral (Ab) and cell-mediated (cytotoxic T cells) mechanisms
4) Leaves memory response for strong and rapid actions if exposed to the same agent in the future