Chapter 18 - Endocrine System Notes Flashcards
Chapter 18 - Endocrine System
the endocrine system is the ________ system of the body
hormonal
Chapter 18 - Endocrine System
_____ are chemical messengers
hormones
Chapter 18 - Endocrine System
hormones are released in one tissue and transported via the _______ to reach specific cells in other tissues
blood stream
Chapter 18 - Endocrine System
each hormone has a ______ on which it acts
specific target cell
Chapter 18 - Endocrine System
hormones are effective in coordinating:
cell, tissue, and organ activites on a long term sustained basis
Chapter 18 - Endocrine System
hormones are messengers that will cause a cell to change or alter its
function to cause a specific response in the body
Chapter 18 - Endocrine System
how do hormones alter cellular operations
changing the types, activites, or quantities of important enzymes and structural proteins
Chapter 18 - Endocrine System
hormone release occurs where
capillaries are abundant and allow the hormone to enter the blood stream quickly
Chapter 18 - Endocrine System
when in the blood stream hormones are either
free flowing or bound to carrier proteins
Chapter 18 - Endocrine System
when _______ reach target cells they do not pass through the cell membrane
non-steroidal
Chapter 18 - Endocrine System
what hormones are not soluble in cell membrane
non-steroidal
Chapter 18 - Endocrine System
hormones bind to what on the cell membrane
receptors
Chapter 18 - Endocrine System
non-steroidal hormones after binding to the receptor on the cell membrane do what
activate messengers in the cytoplasm
Chapter 18 - Endocrine System
the activated messengers in the cytoplasm of the cell do what
cause a change in the cell’s metabolism or function
Chapter 18 - Endocrine System
what is the first messenger
non-steroidal hormone
Chapter 18 - Endocrine System
what is the second messenger
cytoplasm of cell
Chapter 18 - Endocrine System
steroidal hormone are able to pass through
lipid bilayer of the cell membrane into the cytoplasm
Chapter 18 - Endocrine System
which type of hormone directly affects the function of the genes in the nucleus
steroidal
Chapter 18 - Endocrine System
the endocrine system includes
all the endocrine cells and tissues of the body
Chapter 18 - Endocrine System
endocrine cells are
glandular cells
Chapter 18 - Endocrine System
endocrine cells secrete directly into
extracellular fluid of the body
Chapter 18 - Endocrine System
exocrine secrete via
ducts
Chapter 18 - Endocrine System
list of organs/systems involved with ES
hypothalamus pituitary gland pineal gland parathyroid gland thyroid gland heart thymus kidney adrenal glands GI tract pancreas gonads
Chapter 18 - Endocrine System
what is the neurological connection between the ES and NS
hypothalamus
Chapter 18 - Endocrine System
what is connected to the hypothalamus
pituitary gland
Chapter 18 - Endocrine System
hormones are divided into _____ groups
3
Chapter 18 - Endocrine System
what are the 3 groups of hormones
amino acid derivates
peptide hormones
lipid derivates
Chapter 18 - Endocrine System
List of amino acid derivates
epinephrine norepinephrine dopamine thyroid hormones melatonin
Chapter 18 - Endocrine System
list of peptide hormones
ADH
oxytocin
Chapter 18 - Endocrine System
list of Lipid derivates
steroids and eicosanoids
These hormones are the sex hormones:
androgen, estrogen, and corticosteroids
Chapter 18 - Endocrine System
what are eiosanoids
small molecules that affect enzymatic processes
Chapter 18 - Endocrine System
examples of eicosanoids
leukotriense
prostaglandins
Chapter 18 - Endocrine System
when are leukotriense released
tissue injury
Chapter 18 - Endocrine System
where are leukotriense released
white blood cells
Chapter 18 - Endocrine System
when are prostaglandins released
tissue injury
Chapter 18 - Endocrine System
where are prostaglandins released
all tissues
Chapter 18 - Endocrine System
hormones functions may include:
stimulate the synthesis of an enzyme or structural protein
turn an existing enzyme on or off by changing its shape or structure
increase or decrease the rate of synthesis of a particular enzyme or protein
Chapter 18 - Endocrine System
the ES has ______ that are similar to neurological ______ found in the NS
reflexes
reflexes
Chapter 18 - Endocrine System
what regulates the secretion of hormones
hypothalamus
Chapter 18 - Endocrine System
hypothalamus secretes _______ that control endocrine cells in the _______
regulatory hormones
pituitary gland
Chapter 18 - Endocrine System
the _____ in the hypothalamus have direct nervous control over endocrine cells of the _______
autonomic centers
adrenal medullae
Chapter 18 - Endocrine System
how does the hypothalamus act as an endocrine organ
directly secreting hormones into the blood stream
Chapter 18 - Endocrine System
the pituitary gland is also know as the
hypophysis
Chapter 18 - Endocrine System
where is the pituitary gland located
in the sella turcica of the sphenoid bone
Chapter 18 - Endocrine System
what connects the pituitary gland to the hypothalamus
infundibulum
Chapter 18 - Endocrine System
the pituitary gland is divided into ____ and _____ gland
anterior
posterior
Chapter 18 - Endocrine System
the anterior pituitary gland is also called
adenohyphysis
Chapter 18 - Endocrine System
how many regions are on the anterior pituitary gland
3
Chapter 18 - Endocrine System
what are the regions of the anterior pituitary gland
pars distalis
pars tuberalis
pars intermedia
Chapter 18 - Endocrine System
what is the largest region of the anterior pituitary gland
pars distalis
Chapter 18 - Endocrine System
the ______ is the pituitary glands’s connection to the circulatory system of the body
hypophyseal portal system
Chapter 18 - Endocrine System
what is in the hypophyseal portal system
network of blood vessels
Chapter 18 - Endocrine System
what do regulatory hormones do
control the release or inhibition of hormones from the hypothalamus
Chapter 18 - Endocrine System
how many hormones associated with anterior pituitary gland
7
Chapter 18 - Endocrine System
what are the hormones associated with the anterior pituitary gland
thyroid stimulating hormone (TSH) adrenocorticotropic hormone (ACTH) Follicle stimulating hormone (FSH) luteinising hormone (LH) Prolactin (PRL) Growth Hormone (GH) Melanocyte stimulating Hormone (MSH)
Chapter 18 - Endocrine System
anterior hormones are considered _______ because they activate or turn on endocrine cells
tropic hormones
Chapter 18 - Endocrine System
Thyroid stimulating hormone (TSH) is also called
thyrotropin
Chapter 18 - Endocrine System
what does TSH do
causes the release of thyroid hormones at the thyroid gland
Chapter 18 - Endocrine System
Adrenocorticotropic Hormone (ACTH) does what
stimulated the release of steroids by the adrenal glands
Chapter 18 - Endocrine System
Follicle Stimulating Hormone is called a
gonadotropin
Chapter 18 - Endocrine System
what does FSH act on
ovaries
Chapter 18 - Endocrine System
what does FSH do
promotes follicle development in the female reproductive tract. Also stimulates the release of estrogen
Chapter 18 - Endocrine System
Luteinizing hormone (LH) does what
stimulates ovulation as well as secretion of estrogens and progestins and androgens (male sex hormones)
Chapter 18 - Endocrine System
prolactin (PRL) does what
stimulates mammary gland development, and in nursing mothers milk production
Chapter 18 - Endocrine System
Growth Hormone (GH) does what
stimulates cell growth, strongly in the musculoskeletal tissues, such as bone and muscle
Chapter 18 - Endocrine System
Melanocyte stimulating hormone (MSH)
increase the production of melanin on the skin
Chapter 18 - Endocrine System
the posterior pituitary gland is also referred to as the
neurohypophysis or pars nervosa
Chapter 18 - Endocrine System
how many hormones produces by posterior pituitary gland
2
Chapter 18 - Endocrine System
what are hormones produced by posterior pituitary gland
antidiuretic hormone (ADH) oxytocin (OT)
Chapter 18 - Endocrine System
Antidiuretic Hormone is also called
arginine or vasopressin
Chapter 18 - Endocrine System
why is antidiuretic hormone released
change in blood pressure, changes in electrolyte balances in the blood, or a decrease in blood volume
Chapter 18 - Endocrine System
what is primary function of antidiuretic hormone
reduce the amount of water that is released in the kidney
Chapter 18 - Endocrine System
what does oxytocin do
stimulates smooth muscle contract in the walls of the uterus, promoting labor. Also stimulates milk letdown in nursing mothers
Chapter 18 - Endocrine System
the ______ is a dual -lobed structure
thyroid gland
Chapter 18 - Endocrine System
the thyroid gland is found behind the _______
thyroid cartilage or Adam’s apple
Chapter 18 - Endocrine System
what is produced in the thyroid
thyroglobulin
Chapter 18 - Endocrine System
what protein is contained in thyroglobulin
tyrosine
Chapter 18 - Endocrine System
what is the building block of all thyroid hormones
tyrosine
Chapter 18 - Endocrine System
what is absorbed from the diet to assist in the formation of all thyroid hormones
iodine
Chapter 18 - Endocrine System
what are the thyroid hormones
thyroxin (t4)
triiodothyronine (T3)
Chapter 18 - Endocrine System
Thyroxin (t4) is also called
tetraiodothyronine
Chapter 18 - Endocrine System
how many molecules of iodine are in Thyroxin
4
Chapter 18 - Endocrine System
Triiodothyronine contains how many molecules of iodine
3
Chapter 18 - Endocrine System
the production of thyroid hormones are regulated by
hypothalamus
Chapter 18 - Endocrine System
the hypothalamus releases thyroid________ hormone causing the ______ to release thyroid ______ hormone
releasing
anterior pituitary gland
stimulating
Chapter 18 - Endocrine System
what causes the transport of iodide into the follicle
TSH
Chapter 18 - Endocrine System
thyroid hormones can pass through the ________ of _____ cells in the body
cell membrane
all
Chapter 18 - Endocrine System
thyroid hormones ______ the metabolism of the cell it is affecting
increase
Chapter 18 - Endocrine System
what cells do not stain when prepared for the microscope
C or Parafollicular
Chapter 18 - Endocrine System
what does “C Cells” mean
Clear Cells
Chapter 18 - Endocrine System
what hormone is involved with the regulation of the calcium ion concentration in the blood
calcitonin
Chapter 18 - Endocrine System
calcitonin inhibits
osteoclast activity
Chapter 18 - Endocrine System
what reduces the amount of Ca released from the kidney
Calcitonin
Chapter 18 - Endocrine System
what are the parathyroid glands
2 pairs of glands found on the posterior surface of the thyroid gland
Chapter 18 - Endocrine System
what hormone is secreted in response to low levels of calcium in the blood
parathyroid hormone (PTH)
Chapter 18 - Endocrine System
PTH has 4 major effects on the body
stimulates osteoclast activity - increasing calcium in blood
inhibits osteoblasts
increases absorption of Ca in the kidney
stimulates the production of calcitriol in the kidney (promotes the absorption of calcium and phosphorus in the GI)
Chapter 18 - Endocrine System
the adrenal glands sit where
on each kidney (2)
Chapter 18 - Endocrine System
what makes up the adrenal gland
cortex
medulla
Chapter 18 - Endocrine System
how many hormones does adrenal cortex produce
over 24
Chapter 18 - Endocrine System
what are the hormones of cortex called
adrenocortical hormones or corticosteroids
Chapter 18 - Endocrine System
what hormone secreted by the adrenal cortex promotes the conservation of NA ions and the elimination of L
aldosterone
Chapter 18 - Endocrine System
Aldosterone is released in response to
drop in blood pressure
drop in NA ion concentration of the extracellular fluid
drop in blood volume
Chapter 18 - Endocrine System
what is converted to cortisone by the liver
cortisol
Chapter 18 - Endocrine System
what hormone has an anti-inflammatory effect on the body tissues
cortisone
Chapter 18 - Endocrine System
what does the adrenal medullae produce
epinephrine
norepinephrine
Chapter 18 - Endocrine System
what hormones are associated with adrenal rush
epinephrine
norepinephrine
Chapter 18 - Endocrine System
the pineal gland is part of
epithalamus
Chapter 18 - Endocrine System
what does the pineal gland produce
melatonin
Chapter 18 - Endocrine System
what is melatonin produced from
seratonin
Chapter 18 - Endocrine System
2 functions of melatonin
sleep cycle
protecting CNS from damage by free radicals in the blood
Chapter 18 - Endocrine System
3 hormones from the kidneys
calcitriol
erythropoietin
renin
Chapter 18 - Endocrine System
function of calcitriol
to improve the absorption of Ca and P+ in the GI
Chapter 18 - Endocrine System
function of erythropoietin
stimulate the production of red blood cells
Chapter 18 - Endocrine System
when is renin released
in response to reduced rnal blood flow or increased sympathetic stimulation
Chapter 18 - Endocrine System
what converts angiotensinogen to angiotensin I which is then converted to angiotensin II
renin
Chapter 18 - Endocrine System
what stimulates the release of aldosterone and ADH
angiotensin II
Chapter 18 - Endocrine System
the heart releases
atrial natiuretic hormone
Chapter 18 - Endocrine System
the thymus secretes hormones involved with ____ system
immune
Chapter 18 - Endocrine System
the pancreas is both ______ and ______ gland
endrocrine
exocrine gland
Chapter 18 - Endocrine System
the exocrine portion of the pancreas is involved with
digestion
Chapter 18 - Endocrine System
the endocrine portion of the pancreas is involved with
regulation of normal blood glucose levels
Chapter 18 - Endocrine System
the endocrine portion of the pancreas secrete these hormones
glucagon
insulin
Pancreatic polypeptide (PP)
Chapter 18 - Endocrine System
glucagon are from
the alpha cells
Chapter 18 - Endocrine System
function of glucagon
increase blood sugar levels by increasing the rate of glycongen break down in muscle and liver
Chapter 18 - Endocrine System
insulin is produced by
beta cells
Chapter 18 - Endocrine System
insulin is released by
the islets of Langerhans
Chapter 18 - Endocrine System
function of insulin
lower blood glucose levels
Chapter 18 - Endocrine System
function of pancreatic polypeptide (PP)
inhibit gall bladder contraction
Chapter 18 - Endocrine System
testes produce (male)
testosterone
Chapter 18 - Endocrine System
another name for testosterone
androgen
Chapter 18 - Endocrine System
function of androgen
production of sperm, stimulate growth, and determines the secondary sex characteristics of the male (facial hair and body fat content)
also promotes aggressive behavirs and stimulate muscle growth
Chapter 18 - Endocrine System
female repro cells
oocytes
Chapter 18 - Endocrine System
where are oocytes produces
follicle
Chapter 18 - Endocrine System
follicles are produced under the control of
FSH
Chapter 18 - Endocrine System
what triggers ovulation
LH
Chapter 18 - Endocrine System
ovulation causes the follicle to reorganize into a
corpus luteum
Chapter 18 - Endocrine System
the corpus luteum releases _____ which prepares the uterus for the arrival of a developing embryo, accelerates the movement of the oocyte or embryo, and causes enlargement of the mammary glands
progesterone
Chapter 18 - Endocrine System
forms of stress
chemical
emotional
physical
Chapter 18 - Endocrine System
the body has a ________ to stress that will always prodce the same hormonal responses in the body
general adaptive syndrome repsonse
Chapter 18 - Endocrine System
the general adaptive syndrome (GAS) has 3 phases
alarm
resistance
exhaustion
Chapter 18 - Endocrine System
the ____ phase is the intial sympathetic response
alarm
Chapter 18 - Endocrine System
the ____ phase occurs several hours into stressor.
resistance
Chapter 18 - Endocrine System
the _____ are strongly involved in the resistance phase
glucocorticoids
Chapter 18 - Endocrine System
if sever enough ______ is the phase that death can occur easily due to imbalance of _____ and ________ in the body
exhaustion
hormones
electrolytes
Chapter 18 - Endocrine System
_____ is an excessive amount of growth hormone after puberty is reached and growth has stopped.
acromegaly
Chapter 18 - Endocrine System
____ occurs when the posterior pituitary stops producing enough ADH. Extreme water loss occurs in the kidneys, causing electrolyte imbalances and excessive thirst
diabetes insipidus
Chapter 18 - Endocrine System
____ is due to reduced production of thyroid hormones
hypothyroidism
Chapter 18 - Endocrine System
hypothyroidism in adults is called
myxedema
Chapter 18 - Endocrine System
____ is due to an over production of thyroid hormones. this causes increased metabolic rate, blood pressure and bulging eyes
hyperthyroidism
Chapter 18 - Endocrine System
what are other names for hyperthyroidism
thyrotoxicosis
Graves Disease
Chapter 18 - Endocrine System
_____ causes low calcium concentration in the body fluids
hypoparathyroidism
Chapter 18 - Endocrine System
______ causes too much calcium in the blood and the skeletal system will suffer
hyperparathyroidism
Chapter 18 - Endocrine System
______ causes low blood pressure due to loss of sodium and water from the kidneys
hypoaldosteronism
Chapter 18 - Endocrine System
____ causes large amounts of sodium to be retained by the kidneys but a large amount of potassium is lost. this will affect the function of the heart and kidneys
Hyperaldosteronism
Chapter 18 - Endocrine System
_____ is caused by a low glucocorticoid production in the adrenal gland. This can lead to an autoimmune attack of the person’s own adrenal gland
Addison’s Disease
Chapter 18 - Endocrine System
____ is due to over production of glucocorticoids. The symptoms are similiar to those of someone that is subjected to prolonged sever stress. The classic sign is a moon-faced appearance
Cushing’s Disease
Chapter 18 - Endocrine System
_____ is due to high blood glucose levels in the body. The pancreas does not secrete enough insulin to break down the glucose out of the blood. Glucose is spilled into urine and/or continues to circulate in the blood stream
diabetes mellitus
Chapter 18 - Endocrine System
there are ____ types of diebetes mellitus
2
Chapter 18 - Endocrine System
types of diebetes mellitus
type I
type II
Chapter 18 - Endocrine System
___ is insulin dependent, which means the person is required to inject insulin into the blood after every meal to normalize the blood levels
Type I
Chapter 18 - Endocrine System
______ is non insulin-dependent, and is managed with diet and/or oral medication
Type II