Antimicrobials 2

Question 1

What is a category A antimicrobial?

Answer 1

Avoid

Question 2

What is a category B antimicrobial?

Answer 2

Restrict

Question 3

What is a category C antimicrobial?

Answer 3

Caution

Question 4

What is a category D antimicrobial?

Answer 4

Prudence

Question 5

What are the four main mechanisms of action of antibacterials?

Answer 5

• Inhibit bacterial cell wall synthesis
• Damage bacterial cell wall integrity/ function
• Inhibit nucleic acid synthesis or function
• Inhibit protein synthesis

Question 6

What do B-lactam antibiotics do?

Answer 6

inhibit bacterial growth by interfering with the transpeptidation of bacterial wall synthesis

Question 7

What are the class D B-lactam antibiotics?

Answer 7

• Natural penicillins
• Aminopenicillins
• Anti-staph penicillins

Question 8

What are the class C Aminopenicillins?

Answer 8

Aminopenicillins in combination with B-lactamase inhibitors e.g amoxicillin and clauvulanic acid

Question 9

What is amoxicillin licensed for?

Answer 9

the treatment of primary infections of the urogenital tract, e.g pyelenphritis

Question 10

What is the function of tetracycline?

Answer 10

Inhibits protein synthesis in susceptible bacteria?

Question 11

What is doxycycline licensed for?

Answer 11

treatment of rhinitis and bronchopneumonia in cats and dogs

Question 12

What is the function of sulfonamides and DRI’s

Answer 12

• Bacteriacidal
• Time-Dependent
• Broad Spectrum of activity
• Serious side effects are uncommon

Question 13

What is TMPS?

Answer 13

relatively cheap and easy to administrate to horses, used to treat infections of the upper respiratory tract, urogenital system and wound infections

Question 14

What is the nitroimidazoles function?

Answer 14

Inhibits nucleic acid function by preventing DNA repair