Antikörper Flashcards

1
Q

AMLA (antimyolemmal)

A

Myokarditis

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2
Q

ASA (antisarkolemmal)

A

Myokarditis

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3
Q

Anti-LKM1 (Liverkidneymikrosomen)

A

Autoimmunhepatits Typ II (DD: Virushepatitis wie z.B. chron. Hepatitis C)

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4
Q

pANCA

A

Churg-Strauß-Syndrom, MPA, CU, PSC

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5
Q

cANCA

A

Wegener-Granulomatose

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6
Q

AMA

A

PBC (v.a. anti-M2)

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7
Q

Anti-SCL-70 (Topoisomerase, ANA)

A

Sklerodermie (Systeme Variante)

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8
Q

Mi-2-Antikörper

A

Dermatomyositis

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9
Q

ANA

A

Suchantikörper bei Kollagenosen (SLE, Sklerodermie, Sjörgen-Syndrom), AIH Typ I

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10
Q

Anti-SMA

A

AIH Typ I

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11
Q

Anti-ds-DNA

A

SLE

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12
Q

ABM-Ak (Anti-Basalmembran)

A

Goodpasture Syndrom

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13
Q

ASCA (Anti-Saccharomyces-cervisiae)

A

50 % der M. Crohn Patienten

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14
Q

Anti-SS-A (Ro)

A

Sjörgen-Syndrom

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15
Q

Anti-SS-B (La)

A

Sjörgen-Syndrom

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16
Q

DM Typ I

A

Inselzellantikörper (ICA), Glutamtdecarboxylase (GADA), Insulinautantiköper (IAA), Tyrosinphosphatase (IA-2)

17
Q

Anti-Zentromer-AK

A

Sklerodermie (CREST)

18
Q

Anti-RPN-AK

A

Sharp-Syndrom

19
Q

PM-Scl-AK

A

Polymyositis und Dermatomyositis

20
Q

Anti-Jo-1-Antikörper (Histidyl-Transfer-RNA-Synthetase)

A

Polymyositis und Dermatomyositis

21
Q

Anti-Sm

A

SLE (nur 30% aber hochspezifisch)

22
Q

Endothelzell-Antikörper (AECA)

A

Kawasaki-Syndrom

23
Q

Anti-Histon

A

Medikamenteninduzierter Lupus erythematodes, keine anti-dsDNA-AK!!

24
Q

Anti-Desmoglein III, Anti-Plakoglobin

A

Pemphigus vulgaris

25
Q

Zöliakie

A

Anti-Endomysium, Anti-Gewebsglutaminase, Gliadin-AK

26
Q

Anti-RNP-AK

A

Sharp-Syndrom

27
Q

Anti-GM1-Gangliosid

A

Chronisch-inflammatorische demyelinisierende Polyneuropathie (CIDP), AMAN, AMSAN

28
Q

Anti-GQ1b- Gangliosid

A

Miller-Fischer-Syndrom

29
Q

Anti-DNAse-B

A

Poststreptokokken Glomerulonephritis (außerdem Anti-Streptolysin und niedriges C3,C4)

30
Q

Anti U1 RNP

A

Sharp-Syndrom

31
Q

BP230/BP130

A

Bullöses Pemphigoid

32
Q

Anti-MAG-Antikörper

A

CIDP

33
Q

Anti-Yo, Ma1, Ma2, CV2, Hu

A

Yo(=Purkinjezell-Ak)paraneoplastische subakute Kleinhirndegeneration

34
Q

Anti-Ri

A

Opsoclonus-Myoklonus-Syndrom

35
Q

MuSK

A

spezifischer Muskelrezeptor Tyrosinkinase-AK: neben Ach-R-Ak Hinweis für Myasthenia gravis