Antikörper

Question 1

AMLA (antimyolemmal)

Answer 1

Myokarditis

Question 2

ASA (antisarkolemmal)

Answer 2

Myokarditis

Question 3

Anti-LKM1 (Liverkidneymikrosomen)

Answer 3

Autoimmunhepatits Typ II (DD: Virushepatitis wie z.B. chron. Hepatitis C)

Question 4

pANCA

Answer 4

Churg-Strauß-Syndrom, MPA, CU, PSC

Question 5

cANCA

Answer 5

Wegener-Granulomatose

Question 6

AMA

Answer 6

PBC (v.a. anti-M2)

Question 7

Anti-SCL-70 (Topoisomerase, ANA)

Answer 7

Sklerodermie (Systeme Variante)

Question 8

Mi-2-Antikörper

Answer 8

Dermatomyositis

Question 9

ANA

Answer 9

Suchantikörper bei Kollagenosen (SLE, Sklerodermie, Sjörgen-Syndrom), AIH Typ I

Question 10

Anti-SMA

Answer 10

AIH Typ I

Question 11

Anti-ds-DNA

Answer 11

SLE

Question 12

ABM-Ak (Anti-Basalmembran)

Answer 12

Goodpasture Syndrom

Question 13

ASCA (Anti-Saccharomyces-cervisiae)

Answer 13

50 % der M. Crohn Patienten

Question 14

Anti-SS-A (Ro)

Answer 14

Sjörgen-Syndrom

Question 15

Anti-SS-B (La)

Answer 15

Sjörgen-Syndrom

Question 16

DM Typ I

Answer 16

Inselzellantikörper (ICA), Glutamtdecarboxylase (GADA), Insulinautantiköper (IAA), Tyrosinphosphatase (IA-2)

Question 17

Anti-Zentromer-AK

Answer 17

Sklerodermie (CREST)

Question 18

Anti-RPN-AK

Answer 18

Sharp-Syndrom

Question 19

PM-Scl-AK

Answer 19

Polymyositis und Dermatomyositis

Question 20

Anti-Jo-1-Antikörper (Histidyl-Transfer-RNA-Synthetase)

Answer 20

Polymyositis und Dermatomyositis

Question 21

Anti-Sm

Answer 21

SLE (nur 30% aber hochspezifisch)

Question 22

Endothelzell-Antikörper (AECA)

Answer 22

Kawasaki-Syndrom

Question 23

Anti-Histon

Answer 23

Medikamenteninduzierter Lupus erythematodes, keine anti-dsDNA-AK!!

Question 24

Anti-Desmoglein III, Anti-Plakoglobin

Answer 24

Pemphigus vulgaris

Question 25

Zöliakie

Answer 25

Anti-Endomysium, Anti-Gewebsglutaminase, Gliadin-AK

Question 26

Anti-RNP-AK

Answer 26

Sharp-Syndrom

Question 27

Anti-GM1-Gangliosid

Answer 27

Chronisch-inflammatorische demyelinisierende Polyneuropathie (CIDP), AMAN, AMSAN

Question 28

Anti-GQ1b- Gangliosid

Answer 28

Miller-Fischer-Syndrom

Question 29

Anti-DNAse-B

Answer 29

Poststreptokokken Glomerulonephritis (außerdem Anti-Streptolysin und niedriges C3,C4)

Question 30

Anti U1 RNP

Answer 30

Sharp-Syndrom

Question 31

BP230/BP130

Answer 31

Bullöses Pemphigoid

Question 32

Anti-MAG-Antikörper

Answer 32

CIDP

Question 33

Anti-Yo, Ma1, Ma2, CV2, Hu

Answer 33

Yo(=Purkinjezell-Ak)paraneoplastische subakute Kleinhirndegeneration

Question 34

Anti-Ri

Answer 34

Opsoclonus-Myoklonus-Syndrom

Question 35

MuSK

Answer 35

spezifischer Muskelrezeptor Tyrosinkinase-AK: neben Ach-R-Ak Hinweis für Myasthenia gravis