Actinobacteria I Flashcards
Actinomyces
Actinobaculum
Aracnobacterium is now known as Trueperella pyogenes.
Nocardia
Dermatophilus
Bacteria colony shows ________ formation and _________ lesions in infected animals (they were considered as fungi).
filamentous, granulomatous
These four bacteria belong to the same family, Actinobacteria
Nocardia, Actinomyces, Dermatophilus, and Actinobaculum
Thermophilic Actinobacteria:
Cows can develop what type of hypersensitivity when ingesting this bacteria?
Saccharoplyspora rectivirgula
Type III
Gram _____ bacteria, many species with _____ filaments.
positive, branching
Relatively ______ growth on laboratory media.
slow
Opportunistic pathogens producing diverse ____________ responses.
inflammatory
Actinomyces, Arcanobacterium, and Actinobaculum species
1. _______ or ________ anaerobic
2. morphologically _________
3. _____-____ forming, ___-____.
4. Modified _______-________ negative.
5. Colonize _______ membranes.
anaerobic, facultatively, heterogenous, non-spore, non-motile, Zieh-Neelsen, mucous
Nocardia Species
1. ______, non-motile
2. Spores from _____ filaments
3. Growth on ________ dextrose agar
4. Modified _____-_______-positive
5. _____ saprophytes
Aerobic, aerial, Sabourand, Ziehl-Neelsen, Soil
What grows well in this media Sabouraud ? Fungi
Dermatophilus congolensis
1. ______ and capnophilic
2. _____ zoospores
3. No growth on ________ dextrose agar
4. Found in ____ and in ____ on skin of carrier animals
Aerobic, Motile, Sabouraud, scabs, foci
Compared arcanobacterium pyogenes to nocardia species
Trueperella pyogenes (Arcanobacterium pyogenes)
nasopharyngeal mucosa
Actinobaculum suis
preputial mucosa
Actinomyces bovis
oropharynx mucosa
Actinomyces hordeovulneris
unknown
trueperella blood agar?
Trueperella?
filaments of actinomyosis; characteristic of this bacteria’
Arcanobacterium pyogenes, aka Trueperella pyogenes, hosts?
Cattle, sheep. pigs
Arcanobacterium pyogenes
Disease conditions
Abscessation, mastitis, suppurative pneumonia, endometritis, pyometra, arthritis, umbilical infections
Trueperella pyogenes
Worldwide –>
Cattle, pigs, sheep
Trueperella pyogenes
Gram-________, ________
positive, pleomorphic
Trueperella pyogenes _____-_____-forming, non-_____, non-_______, _______ anaerobic ____, which is characterized by a _______ metabolism and strong ________ activity.
Non, spore, motile, capsulated, facultative, rod, fermentative, proteolytic
Trueperella pyogenes
__________ pathogen
Opportunistic
Trueperella pyogenes
This bacterium has been isolated from the wall of ______ ______ and _____ _______, as a gastrointestinal _______ and from the ______ of clinically healthy cows.
bovine rumen, swine stomachs, microbiota, udders
Trueperella pyogenes
Mainly causing _________ lesions
suppurative
Trueperella pyogenes
Any organ may be affected by?
lymphadenitis, osteomyelitis, peritonitis, neural abscess, pyometra, mastitis…
Trueperella pyogenes
Pathogenesis
• Exogenous infection
• Mechanical injuries of skin and mucous membranes
sulfur granules = bovis, viscosus = white
characteristic appearnace of pus
Differnt proteins on cell menrvane of bacteria promotes adhesion of bacteria to epithelial cells. Once attached, produced toxi proteases to enter
Bacteria migrate through epithelial and stroma cells, stroma cells promotes phagocytic cells to enter area (neutrophil aka segmented nuclei) and MQ and DC. Chemokines are released to attract more inflammatory cells to site of infection.
What can be seen here?
Abscess in mandible.
“Lumpy Jaw”
Abscess. Once opened, releases content, mainly puss, and the puss may have some granules.
What can be seen in this image here?
Cow with Mastitis
Lambs: abscess located on neck.
What can be seen in this image?
Pus formation/ granuloma formation
Fibrin in the thoracic cavity
Pus in thoracic cavity; fibrin
What can be seen in this image?
Lungs has multi abscesses as well.
Granulomas present in lung tissue.
MQ from diagnosing trueperella pyogenes