[52] Bioinformatics and Computational Biology Flashcards
What is the focus of Bioinformatics and Computational Biology?
The use of computer algorithms, statistical models, and large data sets to study biological data.
Initials: BCB
Bioinformatics and Computational Biology
What types of biological data are often studied in Bioinformatics?
- Genomic data
- Protein structures
- Metabolic pathways
- Phylogenetic trees
What role does Computational Biology play in understanding genetic diseases?
It aids in identifying genetic variations linked to diseases and understanding the molecular mechanisms of these diseases.
What is the role of Bioinformatics in Genomics?
It helps in the analysis and interpretation of genomic data, such as sequencing, annotation, and comparison of genomes.
What is the role of Bioinformatics in Proteomics?
It assists in the analysis of protein sequences, structures, and functions.
What are the applications of Bioinformatics and Computational Biology?
- Drug discovery
- Personalized medicine
- Crop improvement
- Understanding disease mechanisms
What software tools are commonly used in Bioinformatics?
- BLAST for sequence alignment
- PyMOL for molecular visualization
- Cytoscape for network analysis
- Bioconductor for high-throughput genomics data
What mathematical skills are important in Computational Biology?
- Statistics
- Probability
- Linear algebra
- Calculus
Why is Bioinformatics important in modern biological research?
It enables the handling of large-scale data generated by modern techniques like next-generation sequencing.
How does Bioinformatics contribute to the field of evolution?
It helps in building and analyzing phylogenetic trees, which can reveal evolutionary relationships among organisms.
Initials: NGS
Next-Generation Sequencing
