[40] Implications and Future Research Flashcards
1
Q
What is the significance of mapping transcriptional and cellular diversity?
A
It provides an expansive overview for the development of new therapeutics.
2
Q
What unique insights did the study offer?
A
Cellular specificity through intersection with genes on cardiac clinical testing panels and the druggable genome.
3
Q
What is the druggable genome?
A
A set of genes that can be targeted by drugs.
4
Q
What challenges were overcome in the methodology?
A
- Tissue availability
- Cellular isolation
- Cytoplasmic RNA contamination
5
Q
What is the study’s unique resource for the cardiovascular research community?
A
A large-scale map of transcriptional diversity, publicly available for reanalysis
6
Q
What are the implications for therapeutics?
A
Foundation for targeted drug development and personalized medicine in cardiology
